Abstract Background A main concern during cardiac surgery is the protection of the heart. Myocardial ischemia tends to increase the generation of reactive oxygen species. Based on its oxidation–reduction potentials,..
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Abstract Background Recent studies demonstrated satisfactory results of del Nido cardioplegia in minimally invasive cardiac surgery (MICS). We aimed to evaluate the efficacy of our modified “bloodless” del Nido cardioplegia..
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Abstract Background St. Thomas cardioplegia is commonly administered to adults, yet repeated dosing at brief intervals is required. Del Nido’s cardioplegic solution provides a prolonged duration of safe myocardial arrest,..
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Abstract Objective Equivalent and clinical outcomes have been shown with the use of del Nido (DC) compared with blood (BC) in adult isolated and valve patients. However, its safety and efficacy in cardiac procedures..
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Abstract Background The quality of a myocardial protection of a single-dose del Nido cardioplegia versus multiple dose blood-based cardioplegia on myocardial injury, outcomes and operative times in patients undergoing minimally..
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Abstract Objectives del Nido cardioplegia is utilized for myocardial protection in adult patients undergoing cardiac surgery; however, no standardized re-dosing protocol exists. We describe perfusion characteristics and clinical outcomes in..
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Abstract Background Although recently it has been extended for use in adult cardiac surgery, del Nido cardioplegia was originally indicated for pediatric cardiac surgery. In this meta-analysis, we compare del..
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Abstract Purpose Del Nido cardioplegia (dNC) is a 1:4 formula of blood:crystalloid and contains erythrocytes as oxygen carriers. Hearts donated after circulatory death (DCD) are maintained by ex-vivo machine perfusion..
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Abstract Objectives To compare the safety and efficacy of del-Nido cardioplegia (DNC) with traditional 4:1 cold blood cardioplegia (CBC) in coronary artery bypass grafting and/or valve surgeries in elderly patients...
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Abstract Background Myocardial protection during operations with cardiopulmonary bypass (CPB) and aortic cross clamping is vital. For this purpose, Del Nido (DN) and Custodiol cardioplegia (CC) solutions are used for..
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Abstract Objectives An incomplete restoration of after del Nido was noted in our recent study. This study tested the hypothesis that terminal warm blood promotes a prompt restoration of after a prolonged single-dose del..
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Abstract Objective We examined the safety and efficacy of del Nido compared with histidine-tryptophan-ketoglutarate in . Methods Patients who underwent using del Nido or histidine-tryptophan-ketoglutarate from 2015 to 2019 were enrolled. Various clinical outcomes..
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Abstract The increasing number of minimally invasive procedures prompted the quest for a simple and effective single shot cardioplegia to allow the surgeons to focus on their workflow. The originally..
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Abstract Objectives The safe ischemic time after a single-dose del Nido cardioplegia (DNC) infusion has not yet been established. This study evaluated the progression of myocardial ischemic injury to establish the safe ischemic time after a single-dose DNC..
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Abstract Objective The study objective was to assess the benefits of del Nido cardioplegia compared with cold blood cardioplegia solution in terms of myocardial protection during adult cardiac surgery. Methods..
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Efficacy of Del Nido Cardioplegia in Adult Cardiac Procedures with Prolonged Aortic Cross Clamp Time
Abstract Purpose Equivalent myocardial protection and clinical outcomes have been demonstrated with the use of del Nido (DC) when compared to blood cardioplegia (BC) in adult isolated CABG and valve..
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Abstract Background Del Nido cardioplegia (DNc) was designed for superior myocardial protection during cardiopulmonary bypass (CPB). We conducted a retrospective review to explore if DNc was associated with increase in..
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Abstract Objectives: Few data exist on the use of del Nido cardioplegia in adults, specifically during operations requiring prolonged aortic cross-clamp. In this pilot study, we evaluate outcomes of patients undergoing..
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Abstract Background: The aim of this study is to compare the efficacy of the microplegia solution and Del Nido cardioplegia solution in coronary artery bypass surgery with clinical, biochemical, and..
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Abstract Background: Crystalloid cardioplegic solutions are believed to reduce hemoglobin significantly and increase the transfusion rate. However, recent reports indicate that the del Nido cardioplegia may preserve blood morphology parameters...
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Abstract Background del Nido cardioplegia has been adopted for use in adult cardiac surgery, despite a lack of robust randomised evidence supporting equivalence or superiority to conventional hyperkalaemic blood cardioplegia...
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Abstract Cardioplegic solutions are used in cardiac surgery to achieve controlled cardiac arrest during operations, making surgery safer. Cardioplegia can either be blood or crystalloid based, with perceived pros and..
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Abstract Objective: The aim of this study was to evaluate outcome measures between our standard multidose cardioplegia protocol and a del Nido cardioplegia protocol in congenital heart surgery patients. Methods:..
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Abstract Background in adult cardiac surgery is commonly achieved with either multidose blood or single-dose del Nido crystalloid cardioplegia. Aim The aim of this systematic review and meta-analysis was to compare..
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