Tags Archives: Coating

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Hemocompatible polymer coating for extracorporeal circulation circuit affects lactate levels during cardiopulmonary bypass surgery

Abstract Introduction Blood lactate level (LL) is a useful predictor of physiological issues during extracorporeal circulation (ECC) treatment. To determine variations in LL depending on the hemocompatible coatings used for..

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Universal modular strategy for constructing anticoagulant coatings on surfaces of medical devices

Abstract Thrombus on implants is dangerous, necessitating anticoagulant coatings for most of blood-contacting devices with various substances. So far, there is no universal strategy of the pertinent surface modification for..

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Nanoconjugated anticoagulant coating with blood repellency for extracorporeal circulation in cardiothoracic surgery

Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..

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Nanoconjugated anticoagulant coating with blood repellency for extracorporeal circulation in cardiothoracic surgery

Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..

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Advances in CPB Circuit Coatings: Impact on Biocompatibility and Inflammatory Response

Introduction Cardiopulmonary bypass (CPB) is a lifesaving technology in cardiac surgery, but it introduces blood-material interactions that trigger inflammatory and coagulative responses. To address these issues, advancements in biocompatible CPB..

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Health Technology Assessment of Cardiopulmonary Bypass Circuit with and without Phosphorylcholine Coating: A Retrospective Study on Safety and Efficiency in…

Abstract Background:   Phosphorylcholine has emerged as a potential adjunctive agent in cardiopulmonary bypass (CPB) circuits. Phosphorylcholine serves as a coating for the CPB circuit, potentially enhancing biocompatibility and reducing..

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Mechanical-Enhanced and Durable Zwitterionic Hydrogel Coating for Inhibiting Coagulation and Reducing Bacterial Infection

Abstract Blood-contact medical devices are indispensable for clinical interventions, yet their susceptibility to thrombosis and bacterial infections poses substantial risks to treatment efficacy and patient well-being. This study introduces a..

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Phosphorylcholine/Heparin Composite Coatings on Artificial Lung Membrane for Enhanced Hemo-compatibility

Abstract As the key component of extracorporeal membrane oxygenation (ECMO), artificial lung membranes have low gas permeability and plasma leakage problems, and the contact between membrane materials and blood can..

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Is using an open-reservoir cardiopulmonary bypass circuit after 6 days on standby safe?

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

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Is using an open-reservoir cardiopulmonary bypass circuit after 6 days on standby safe?

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

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