Tags Archives: cerebral autoregulation

Perfusfind S.L.

Abstract Introduction Postoperative delirium affects up to 60% of cardiac surgical patients. No reliable gold standard method exists for preventing delirium after cardiac surgery. An example of patient-personal monitoring is..

Perfusfind S.L.

Abstract Background Prior clinical research demonstrated that rapid reduction in arterial carbon dioxide (PaCO2) levels during extracorporeal membrane oxygenation (ECMO) is associated with acute brain injury (ABI), which may be..

Perfusfind S.L.

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a promising intervention for refractory cardiac arrest, with potential benefits in survival and neurological outcomes. However, the impact of ECPR’s rapid,..

Perfusfind S.L.

Abstract Abstract Objective To investigate cerebral autoregulation impairment during neonatal cardiac surgery. Design A retrospective observational study. Setting Single-center, university teaching children’s hospital. Participants Neonates undergoing surgery for critical congenital..

Perfusfind S.L.

Abstract Assessment of cerebral autoregulation is challenging under different hemodynamic conditions during cardiac surgery and must be rapidly calculated in order to optimize mean arterial pressure (MAP). Whether systemic flow..

Perfusfind S.L.

Abstract Background Understanding cerebral blood flow regulation and later optimizing brain perfusion is part of neuroprotection during cardiopulmonary bypass (CPB) in neonates. Methods A total of 38 neonates undergoing CPB..

Perfusfind S.L.

Abstract Managing acute brain injury involves protecting the brain from secondary injury by addressing the mismatch between metabolic demand and cerebral perfusion. Observational studies have associated impaired cerebral autoregulation, a..

Perfusfind S.L.

Abstract Objective The clinical importance of individualized blood pressure management in optimizing cerebral perfusion during cardiac surgery has been well established. However, consensus on blood pressure goals is lacking. The..

Perfusfind S.L.

Abstract Objective To investigate whether  is impaired after neonatal cardiac surgery and whether changes in  metrics are associated with different  or the incidence of postoperative neurologic events. Methods This is a retrospective observational..

Perfusfind S.L.

Abstract Despite improvements in survival after illnesses requiring extracorporeal life support, cerebral injury continues to hinder successful outcomes. Cerebral autoregulation (CA) is an innate protective mechanism that maintains constant cerebral..

Perfusfind S.L.

Abstract To evaluate the feasibility of continuous determination of the optimal mean arterial blood pressure (opt-MAP) according to cerebral autoregulation and to describe the opt-MAP, the autoregulation limits, and the..

Perfusfind S.L.

Abstract Background: Cerebral blood flow (CBF) is believed to be relatively constant within an upper and lower blood pressure limit. Different methods are available to monitor CBF autoregulation during surgery...

Perfusfind S.L.

Abstract Background: Impaired cerebral autoregulation (CA) is one of several proposed mechanisms of acute brain injury in patients supported by extracorporeal membrane oxygenation (ECMO). The primary aim of this study..

Perfusfind S.L.

Abstract Background: Impaired cerebral autoregulation (CA) is one of several proposed mechanisms of acute brain injury in patients supported by extracorporeal membrane oxygenation (ECMO). The primary aim of this study was..

Perfusfind S.L.

Abstract Background Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its risks and associations with outcomes. The cerebral oximetry..

Perfusfind S.L.

Abstract Impaired cerebral autoregulation (CA) can cause negative outcomes in neurological conditions. Real-time CA monitoring can predict and thereby help prevent postoperative complications for neurosurgery patients, especially those suffering from..

Perfusfind S.L.

Abstract Clinicians caring for children with cardiopulmonary failure using extracorporeal membrane oxygenation (ECMO) are refining bedside clinical practices by focusing on minimizing morbidity associated with neurologic complications. Neurologic complications are the main drivers of survival..

Perfusfind S.L.

Abstract Validation of a real-time monitoring device to evaluate the risk or occurrence of neurologic injury while on extracorporeal membrane oxygenation (ECMO) may aid clinicians in prevention and treatment. Therefore,..

Perfusfind S.L.

Abstract Background Cardiac surgery studies have established the clinical relevance of personalised arterial blood pressure management based on cerebral autoregulation. However, variabilities exist in autoregulation evaluation. We compared the association..

Perfusfind S.L.

Abstract Background Rewarming on cardiopulmonary bypass (CPB) is associated with increased metabolic demands; however, it remains unclear whether cerebral autoregulation is affected during this phase. This RCT aims to describe..

Perfusfind S.L.

Abstract Background Cerebral autoregulation (CA) impairment is associated with neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Severe variations of arterial CO2 (PaCO2) and O2 (PaO2) tension after ECMO onset..

Perfusfind S.L.

Abstract Backgroundː Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its occurrence and associations with outcomes. The objective of this..

Perfusfind S.L.

Abstract Background Cerebral autoregulation mechanisms help maintain adequate cerebral blood flow (CBF) despite changes in cerebral perfusion pressure. Impairment of cerebral autoregulation, during and after cardiopulmonary bypass (CPB), may increase..

Perfusfind S.L.

Abstract OBJECTIVES:  Monitoring cerebral autoregulation may help identify the lower limit of autoregulation in individual patients. Mean arterial blood pressure below lower limit of autoregulation appears to be a risk..

Perfusfind S.L.

Abstract Objectives We sought to define the lower and upper limits of cerebral blood flow autoregulation and the optimal blood pressure during cardiopulmonary bypass. We further sought to identify variables..

Perfusfind S.L.

Abstract Despite a rise in blood pressure, cerebral oxygenation decreases following phenylephrine administration, and we hypothesised that phenylephrine reduces cerebral oxygenation by activating cerebral α1 receptors. We studied patients on cardiopulmonary..

Perfusfind S.L.

Abstract BACKGROUND:  Individualizing mean arterial blood pressure (MAP) based on cerebral blood flow (CBF) autoregulation monitoring during cardiopulmonary bypass (CPB) holds promise as a strategy to optimize organ perfusion. The..

Perfusfind S.L.

Summary This aim of this prospective observational cohort study was to evaluate any association between postoperatively impaired cerebrovascular autoregulation and the onset of delirium following cardiac surgery. Previous studies have..