Tags Archives: cardiopulmonary bypass (CPB)

Perfusfind S.L.

Abstract In this prospective observational study, we investigated whether congenital heart disease (CHD) affects the microcirculation and whether the microcirculation is altered following cardiac surgery with cardiopulmonary bypass (CPB). Thirty-eight..

Perfusfind S.L.

Abstract Background Low cardiac power (product of flow and pressure) has been shown to be associated with mortality in patients with cardiogenic shock after acute myocardial infarction, but has not..

Perfusfind S.L.

Abstract Background Oxylipins, the oxidative metabolites of polyunsaturated fatty acids (PUFAs), serve as key mediators of oxidative stress, inflammatory responses, and vasoactive reactions in vivo. Our previous work has established..

Perfusfind S.L.

Abstract Introduction: The use of cardiopulmonary bypass (CBP; also known as a heart-lung machine) in newborns with complex congenital heart defects may result in brain damage. Magnetic resonance imaging (MRI) assessments..

Perfusfind S.L.

Abstract Pathophysiology There are two types of HIT, depending on the absence or presence of an immune mediation. Type 1 is a non-immune-mediated direct activation of platelets by heparin that..

Perfusfind S.L.

Abstract Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal dysfunction, one of the most common complications of this surgical cohort. Acute kidney injury (AKI) is associated with..

Perfusfind S.L.

Abstract Background Current guidelines recommend enteral nutrition (EN) should be implemented as early as possible in patients after cardiopulmonary bypass (CPB), but the optimal time to initiate EN is still..

Perfusfind S.L.

Abstract Background Nontechnical skills are critical in cardiac surgery but currently there is no formal paradigm to teach these in residency training. We investigated the use of the Nontechnical skills..

Perfusfind S.L.

Abstract The present study aimed to assess the changes in the immunological parameters of patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The serum or plasma samples of patients were..

Perfusfind S.L.

Abstract Background Postoperative morbidity and mortality after cardiac surgery with  (CPB) remain high despite recent advances in both anesthesia and perioperative management. Among modifiable risk factors for , optimal  during and after surgery..

Perfusfind S.L.

Abstract A hypoxic–hyperoxic preconditioning (HHP) may be associated with cardioprotection by reducing endothelial damage and a beneficial effect on postoperative outcome in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB)...

Perfusfind S.L.

Abstract Cardiopulmonary bypass is an integral and indispensable part of surgical repair of congenital heart defects. While the complications and morbidity secondary to the use of cardiopulmonary bypass has decreased..

Perfusfind S.L.

Abstract Objective Several human studies have associated nitric oxide administration via the cardiopulmonary bypass circuit with decreased incidence of cardiopulmonary bypass–associated acute kidney injury, but histopathologic and serologic evidence of..

Perfusfind S.L.

Abstract During a cardiopulmonary bypass (CPB) procedure using a heart-lung machine, the volume of blood inside the venous reservoir is a crucial piece of information for the perfusionist to make..

Perfusfind S.L.

Abstract Objective  and  dysregulate coronary  tone, which can be further affected by common   undergoing cardiac surgery. This study investigates differences in coronary myogenic tone and  to  before and after cardioplegia and  based on hypertension history. Methods..

Perfusfind S.L.

Abstract Objective To identify potentially modifiable risk factors related to prolonged cardiovascular pharmacological support after weaning from cardiopulmonary bypass (CPB). Methods This is a secondary analysis of two prospective cohort..

Perfusfind S.L.

Abstract Background Major cardiac surgery related blood loss is associated with increased postoperative morbidity and mortality. Platelet dysfunction is believed to contribute to post-cardiopulmonary bypass (CPB)-induced microvascular bleeding. We hypothesised..

Perfusfind S.L.

Abstract Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), take over the function of one or more organs, providing clinicians time to treat underlying pathophysiological..

Perfusfind S.L.

Abstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac..

Perfusfind S.L.

Abstract Objective: We aim to comprehensively describe the transcriptional activity and signaling of pulmonary parenchymal and immune cells before and after cardiopulmonary bypass (CPB) by using a multi-omic approach coupled..

Perfusfind S.L.

Abstract Objectives The management of traumatic cardiac injury (TCI) may require a prompt treatment, including the use of cardiopulmonary bypass (CPB) followed by surgical repair. This study evaluated the surgical..

Perfusfind S.L.

Abstract Vasoplegia is defined by hypotension and low systemic vascular resistance despite the normal or elevated cardiac index, a complication frequently following cardiac surgery, carrying high morbidity and mortality rate...

Perfusfind S.L.

Abstract BACKGROUND:  Intraoperative inflammation may contribute to postoperative neurocognitive disorders after cardiac surgery requiring cardiopulmonary bypass (CPB). However, the relative contributions of general anesthesia (GA), surgical site injury, and CPB..

Perfusfind S.L.

Abstract Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine released in response to glucocorticoids, which counter-regulates the effects of glucocorticoids. This study was performed to determine the impact of steroids..

Perfusfind S.L.

Abstract Introduction Bloodless cardiac surgery refers to open-heart surgery without blood or blood products. The cardiopulmonary bypass (CPB) circuits are primed with crystalloid solely, and there is no intraoperative blood..

Perfusfind S.L.

Abstract Open-heart surgery is often an unavoidable option for the treatment of cardiovascular disease and prevention of cardiomyopathy. Cardiopulmonary bypass surgery requires manipulating cardiac contractile function via the perfusion of..

Perfusfind S.L.

Abstract Objectives Previous studies have described impaired  after  (CPB). Whether this is still valid in contemporary cardiac surgery is unclear. This study aimed to quantify changes in function and number of platelets..

Perfusfind S.L.

Abstract Objective Cognitive impairment is a common neurologic complication after cardiac surgery with cardiopulmonary bypass (CPB). This study evaluated postoperative cognitive function to determine predictors of cognitive dysfunction, including intraoperative..

Perfusfind S.L.

Abstract Objective:  Postoperative delirium (POD) is common after cardiac surgery. We have previously identified plasma sodium concentration and the volume of infused fluids during surgery as possible risk factors. Both..

Perfusfind S.L.

Abstract Dampening of the arterial line waveform during surgery is always a major concern for the operating team. During cardiovascular surgery the etiology may be very serious and require immediate..