Tags Archives: cardiopulmonary bypass (CPB)

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Risk Factors for Prolonged Intensive Care Unit Stay After Open Heart Surgery in Adults

Abstract Objective Prolonged intensive care unit (ICU) stay prevents the use of ICU equipment by other patients and increases hospital cost. This retrospective study aimed to investigate the risk factors..

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Short-term recovery pattern of plasma fibrinogen after cardiac surgery: A prospective observational study

Abstract Low plasma fibrinogen level is common after cardiopulmonary bypass (CPB). Current substitution practice with fibrinogen concentrate generally follows a single measurement and cut-off values from the literature, whereas early..

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Functional Performance of Different Venous Limb Options in Simulated Neonatal/Pediatric Cardiopulmonary Bypass Circuits

Abstract Objective: Hemodilution is a concern in cardiopulmonary bypass (CPB). Using a smaller dual tubing rather than a single larger inner diameter (ID) tubing in the venous limb to decrease..

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The influence of oxygen delivery during cardiopulmonary bypass on the incidence of delirium in CABG patients; a retrospective study

Abstract Introduction: Postoperative delirium is the most common neurological complication of cardiac surgery. Hypoxia has been shown to increase the risk of postoperative delirium. The possibility to continuously monitor oxygen..

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Impact of an inline extracorporeal membrane oxygenation hemofilter system in neonatal acute kidney injury

Abstract Extracorporeal membrane oxygenation (ECMO) is considered a recognized lifesaving support for patients with cardiorespiratory failure. Acute kidney injury (AKI) and fluid overload are significant morbidity factors resulting in serious..

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Utility of thromboelastography versus routine coagulation tests for assessment of hypocoagulable state in patients undergoing cardiac bypass surgery

Abstract Introduction: Peri-operative monitoring of coagulation is important to diagnose potential cause of hemorrhage, to manage coagulopathy and guide treatment with blood products in patients undergoing cardiac surgery with cardiopulmonary bypass...

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Urinary hypoxia: an intraoperative marker of risk of cardiac surgery-associated acute kidney injury

Abstract Background Acute kidney injury (AKI) is common after cardiac surgery and profoundly affects postoperative mortality and morbidity. There are no validated methods to assess risk of AKI intraoperatively. Methods..

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Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer’s chase technique – a…

Abstract Introduction: Residual pump blood from the cardiopulmonary bypass (CPB) circuit is often collected into an infusion bag (IB) and re-transfused. An alternative is to chase the residual blood into..

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Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review

Objective The aim was to evaluate the predictive value of  for  in adult cardiac surgery with . Design Retrospective  and systematic review of the literature. Setting A tertiary university hospital. Participants 202 patients undergoing..

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Influence of the type of congenital heart defects on epithelial lining fluid composition in infants undergoing cardiac surgery with cardiopulmonary…

Abstract Background In children with congenital heart disease (CHD), altered pulmonary circulation compromises gas exchange. Moreover, pulmonary dysfunction is a complication of cardiac surgery with cardiopulmonary bypass (CPB). No data..

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The level of urinary IL-18 in acute kidney injury after cardiopulmonary bypass

ABSTRACT This study investigated the diagnostic value of urinary interleukin-18 (uIL-18) in acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in clinical practice. A total of 103 patients who underwent..

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Incidence and etiological mechanism of stroke in cardiac surgery

Abstract Objective We studied patients who had experienced a stroke in the postoperative period of cardiac surgery, aiming to analyse their progression and determine the factors that may influence prognosis..

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A novel augmented venous-drainage model of cardiopulmonary bypass for deep hypothermic circulatory arrest without blood priming

Abstract Objective: Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are commonly used in cardiac surgery. However, the mortality and morbidity are still high in practice. Developing novel protective..

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Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model

Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..

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Dose Estimation for Bivalirudin during Pediatric Cardiopulmonary Bypass

Abstract Aim A typical adult based bivalirudin regimen during cardiopulmonary bypass uses a loading dose of 1 mg.kg‐1 and a circuit prime (volume L x 13 mg) with a subsequent intravenous..

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Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study

Abstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..

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Treatment of post-cardiopulmonary bypass SIRS by hemoadsorption: a case series

Abstract The use of cardiopulmonary bypass (CPB) in cardiothoracic surgery results in a well-known activation of the immunologic response. In some cases, however, this triggered immunologic response may be excessive,..

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The Norwood Stage 1 procedure - conduct of perfusion: 2017 Survey results from NPC-QIC member institutions

Abstract Hypoplastic left heart syndrome (HLHS) is a rare and severe congenital cardiac defect. Approximately 1000 infants are born with HLHS in the United States every year. Healthcare collaboratives over..

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Hyperoxia During Cardiopulmonary Bypass Is Associated With Mortality in Infants Undergoing Cardiac Surgery

Abstract Objectives Patients undergoing cardiac surgery using cardiopulmonary bypass have variable degrees of blood oxygen tension during surgery. Hyperoxia has been associated with adverse outcomes in critical illness. Data are not available..

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Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass

Abstract Background Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as..

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The Correlation Between Bowel Complications and Cardiac Surgery

Abstract Although advances in knowledge and technology have improved outcomes in surgical cardiac patients over the last decade, complications following cardiac operations still remain to be potentially fatal. Gastrointestinal complications,..

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Increased Cerebral Mitochondrial Dysfunction and Reactive Oxygen Species with Cardiopulmonary Bypass

Abstract Objectives Neurodevelopmental injury after cardiac surgery using cardiopulmonary bypass (CPB) for congenital heart defects is common, but the mechanism behind this injury is unclear. This study examines the impact..

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Anemia in Cardiac Surgery – Can Something Bad Get Worse?

Abstract Introduction Anemia and blood transfusion are risk factors for morbidity/mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The objective of this study is to analyze the association..

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Effects of Remote Ischemic Preconditioning on Platelet Activation and Reactivity in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass: A Randomized…

Abstract During cardiopulmonary bypass (CPB), platelet activation and dysfunction are associated with adverse outcomes. Remote ischemic preconditioning (RIPC) has been shown to attenuate platelet activation. We evaluated the effects of..

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Exposure–Response Relationship of Tranexamic Acid in Cardiac Surgery: A Model-based Meta-analysis

Background It is unclear whether high-dose regimens of tranexamic acid in cardiac surgery (total dose, 80 to 100 mg/kg) confer a clinical advantage over low-dose regimens (total dose, approximately 20..

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Efficacy and Safety of Corticosteroids Prophylaxis in Cardiac Surgery: A Protocol for Systematic Review and Meta-Analysis

Background Although corticosteroid prophylaxis in adult cardiac surgery has been studied extensively for 40 years, its role remains controversial, and the optimal dose remains uncertain. The objective of this meta-analysis..

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Prompt Prediction of Fibrinogen Concentration During Cardiopulmonary Bypass: A Pilot Study

Abstract Platelet Mapping can measure both the degree of platelet inhibition and fibrinogen activation, was not originally designed to measure fibrinogen concentration. Traditional laboratory fibrinogen concentration testing requires around 60..

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Intraoperative Oxygen Concentration and Neurocognition after Cardiac Surgery: A Randomized Clinical Trial

Abstract Background Despite evidence suggesting detrimental effects of perioperative hyperoxia, hyperoxygenation remains commonplace in cardiac surgery. Hyperoxygenation may increase oxidative damage and neuronal injury leading to potential differences in postoperative..

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Pitfalls of Commonly Used Anticoagulation Monitoring Techniques in Antiphospholipid Syndrome During Cardiopulmonary Bypass

Abstract Antiphospholipid Syndrome (APS) is an immunologic disorder that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. Patients who experience APS may develop cardiac..

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High Versus Low Blood Pressure Targets for Cardiac Surgery with Cardiopulmonary Bypass

Abstract This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of a higher versus lower blood pressure target during..

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