Abstract Background The administration of blood products during pediatric cardiac surgery is common. We sought to determine if thromboelastography (TEG) is a cost-effective tool to reduce blood product transfusion in..
Read MoreAbstract Background: Aim of this study was to evaluate the outcomes of endocarditis patients undergoing valve surgery with the Cytosorb® hemoadsorption (HA) device during cardiopulmonary bypass. Methods: From 2009 until 2019,..
Read MoreAbstract Background Recently, there has been an interest in the temporal relationship between contrast exposure (CM) and cardiac surgery suggesting that a “double hit” on the kidney function in close..
Read MoreAbstract Background (AKI) after (CPB) is associated with a requirement for dialysis, a longer stay in the intensive care unit, a longer hospital length of stay, and mortality. An arterial outlet temperature..
Read MoreAbstract BACKGROUND: It is unclear whether maintaining pulmonary perfusion and ventilation during cardiopulmonary bypass (CPB) reduces pulmonary inflammatory tissue injury compared with standard CPB where the lungs are not ventilated..
Read MoreAbstract Several coating techniques for extracorporeal circulation have been developed to reduce the systemic inflammatory response during cardiopulmonary bypass (CPB). We compared the clinical effectiveness and biocompatibility of poly-2-methoxyethylacrylate (PMEA)-..
Read MoreAbstract In Japan, perfusionists who work on other clinical tasks are involved in cardiopulmonary bypass. Moreover, the number of cases they can perform is limited. In view of this situation,..
Read MoreAbstract We compared the effects on microvascular reactivity of hydroxyethylstarch (Volulyte®) and gelatin (Geloplasma®) during acute haemodilution. The hypothesis was that Volulyte would provide better microvascular reactivity than Geloplasma. Forty..
Read MoreAbstract Obesity is a frequent comorbidity among patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Cardiac surgery with CPB impairs microcirculatory perfusion, which is associated with multiple organ failure. As..
Read MoreAbstract Objectives The aim of this study is to evaluate the possibility of the autologous platelet-rich plasma (PRP) collection from the cardiopulmonary bypass (CPB) circuit and to evaluate its effect..
Read MoreAbstract Objectives The aim of this study was to evaluate the analytical performance of the new epoc® point-of-care blood analysis system in patients. Design and methods The precision study was conducted..
Read MoreAbstract We developed a numerical model, based on multi-physics computational fluid dynamics (CFD) simulations, to assist the design process of a plastic hollow-fiber bundle blood heat exchanger (BHE) integrated within..
Read MoreAbstract Objective Cardiac surgery and are associated with release of and microcirculatory alterations that result in organ dysfunction. Near-infrared of tissue (StO2) and the test (VOT) were utilized in a study of elective cardiac surgical..
Read MoreAbstract Introduction: Arterial filter is the part of the cardiopulmonary bypass circuit where blood cells are exposed to high mechanical stress and where cellular aggregates may fasten in large quantities...
Read MoreAbstract Background Cardiac surgery associated acute kidney injury (CS-AKI) is common in infants and associates with negative outcomes. Nadir indexed oxygen delivery (DO 2i) during cardiopulmonary bypass (CPB) is associated with..
Read MoreAbstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is known to contribute towards the incidence of acute kidney injury (AKI) and peri-operative morbidity and mortality. There are several patient, anaesthetic..
Read MoreAbstract Introduction: del Nido cardioplegia is a newer solution getting popular worldwide, whereas in Nepal, St. Thomas cardioplegia solution is conventionally used. There is no national recommendation on cardioplegia solutions..
Read MoreAbstract The aim of coronary artery bypass grafting (CABG) is to prolong life and reduce symptoms. However, when compared with percutaneous coronary intervention, CABG is a significantly more invasive operation,..
Read MoreAbstract Neonates have low levels of antithrombin. Inadequate anticoagulation during cardiopulmonary bypass (CPB) due to low antithrombin activity may result in a poor preservation of the coagulation system during bypass...
Read MoreAbstract Cardiopulmonary bypass (CPB) in infants is associated with morbidity due to systemic inflammatory response syndrome (SIRS). Strategies to mitigate SIRS include management of perfusion temperature, hemodilution, circuit miniaturization, and..
Read MoreAbstract The long-term neurodevelopmental outcome has been a great concern for cardiac surgeons although it is still unclear. There are some risks regarding the neurological and neuropsychological deficits before, during..
Read MoreAbstract Background The risk–benefit for utilizing cardio‐pulmonary bypass (CPB) in lung transplantation (LTx) remains debatable. This study compares outcomes after LTx utilizing different CPB strategies – elective CPB vs. off‐pump..
Read MoreAbstract Introduction: Acute kidney injury (AKI) is a serious complication after coronary artery bypass grafting (CABG). There are conflicting reports whether a miniaturized cardiopulmonary bypass (MCPB) system is associated with..
Read MoreAbstract Neurologic injury in the form of cognitive decline, delirium, and stroke are common phenomena in patients undergoing cardiac surgery and continues to be one of the most common complication..
Read MoreAbstract Blood transfusion is the most common procedure in cardiac surgery. Increasing evidence exists that excess transfusions are harmful to patients. Transfusion reactions and complications, including infection, immune modulation, and..
Read MoreAbstract Acute kidney injury (AKI) is a serious postoperative complication following cardiac surgery. Despite the incidence of AKI requiring temporary renal replacement therapy being low, it is nonetheless associated with..
Read MoreAbstract Objectives To estimate the global incidence and outcomes of (AKI) after cardiac surgery in adult patients. Design A systematic review and meta-analysis. Setting Cardiac surgery wards. Participants Adult patients after..
Read MoreAbstract Background In the present randomized study, we evaluated the differential effects of a colloid and a crystalloid fluid on renal oxygen delivery (RDO2RDO2), glomerular filtration (GFR), renal oxygen consumption..
Read MoreAbstract Background We aimed to assess the incidence and perioperative risk factors for hyperbilirubinemia after cardiac surgery, and determine its influence on early operative outcome. Methods This prospective observational study..
Read MoreAbstract Objectives Minimum alveolar concentration (MAC) of volatile anesthetic agents to maintain bispectral index (BIS) below 50 in 50% of patients was defined as MACBIS50. The primary objective of this..
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