Tags Archives: cardiopulmonary bypass (CPB)

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Is using an open-reservoir cardiopulmonary bypass circuit after 6 days on standby safe?

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

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Endothelial hyperpermeability after cardiac surgery with cardiopulmonary bypass as assessed using an in vitro bioassay for endothelial barrier function

Abstract Background.  The mechanisms causing increased endothelial permeability after cardiopulmonary bypass (CPB) have not been elucidated. Using a bioassay for endothelial barrier function, we investigated whether endothelial hyperpermeability is associated..

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Is using an open-reservoir cardiopulmonary bypass circuit after 6 days on standby safe?

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

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Anti-inflammatory effects of propofol during cardiopulmonary bypass: A pilot study

Abstract Introduction:  Propofol has been suggested as a useful adjunct to cardiopulmonary bypass (CPB) because of its potential protective effect on the heart mediated by a decrease in ischemia-reperfusion injury..

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S100 and S100β: biomarkers of cerebral damage in cardiac surgery with or without the use of cardiopulmonary bypass

Abstract Objective The present study is to describe the clinical impact of S100 and S100β for the evaluation of cerebral damage in cardiac surgery with or without the use of..

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Detection of coagulopathy in paediatric heart surgery [DECISION study]: study protocol

Abstract Background Each year in the UK, ≈3000 children undergo major cardiac surgery requiring cardiopulmonary bypass. Approximately 40 % of these experience excessive bleeding necessitating red cell transfusion or treatment with..

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Extended use of cardiopulmonary bypass in a multidisciplinary hospital

Abstract Objective To share our experience highlighting the additional use of cardiopulmonary bypass (CPB) in cases other than the conventional ischemic, congenital and valvular heart diseases. Methodology All patients undergoing..

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Preoperative CRP levels is not predictive early renal dysfunction after coronary artery bypass surgery

Abstract Background: The aim of this retrospective study is to determine the correlation between preoperative CRP levels and the early renal dysfunction after cardiac surgery. Methods: From January 2012 to..

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Randomized, Double‐Blinded, Placebo‐Controlled Trial of Fibrinogen Concentrate Supplementation After Complex Cardiac Surgery

Abstract Background Postoperative bleeding after heart operations is still a common finding, leading to allogeneic blood products transfusion. Fibrinogen and coagulation factors deficiency are possible determinants of bleeding. The experimental..

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Do patients with haematological malignancy who need cardiopulmonary bypass have a short-term higher mortality or a higher chance of disease…

Abstract A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether patients with haematological malignancy (HM) who need cardiopulmonary bypass (CPB)..

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Intraoperative change of lactate level is associated with postoperative outcomes in pediatric cardiac surgery patients: retrospective observational study

Abstract Background A change of serum lactate concentrations appeared to be useful for predicting outcomes in various acute ill settings. However, there is little information on intraoperative change of lactate..

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Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

Abstract Background: Unfractionated heparin (UFH) is widely used as a reversible anti-coagulant in cardiopulmonary bypass (CPB). However, the pharmacokinetic characteristics of UFH in CPB surgeries remain unknown because of the..

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Venous Cannulation for Cardiopulmonary Bypass in the Case of Anomaly of the Inferior Vena Cava

Abstract  of the  and its tributaries are quite uncommon; however, since the development of , they have been described more frequently. Most of them are usually asymptomatic, although they can have clinical..

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Maternal obesity and excessive maternal weight gain during pregnancy: effects on outcomes after neonatal cardiac surgical procedures

Abstract Introduction Maternal obesity is associated with an increased risk for adverse perinatal outcomes. Obesity is also associated with a chronic inflammatory state and metabolic derangements that affect the newborn...

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An innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit

Abstract Context:  Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of..

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Optimal blood pressure during cardiopulmonary bypass defined by cerebral autoregulation monitoring

Abstract Objectives We sought to define the lower and upper limits of cerebral blood flow autoregulation and the optimal blood pressure during cardiopulmonary bypass. We further sought to identify variables..

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Renal haemodynamics and oxygenation during and after cardiac surgery and cardiopulmonary bypass

Abstract Acute kidney injury (AKI) is a common complication following cardiac surgery performed on cardiopulmonary bypass (CPB) and has important implications for prognosis. The aetiology of cardiac surgery‐associated AKI is..

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2016 survey about temperature management during extracorporeal circulation in China

Abstract Objective: In order to assess the current status of temperature management during cardiopulmonary bypass (CPB) in China and, thereby, implement standardized management protocols, the authors carried out a national..

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New Technology Mimics Physiologic Pulsatile Flow During Cardiopulmonary Bypass

Abstract The VentriFlo True Pulse Pump (Design Mentor, Inc., Pelham, NH, USA) is the first blood pump designed to mimic human arterial waveforms in a standard oxygenation circuit. Our aim was..

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Cerebral Microhemorrhage: A Frequent Magnetic Resonance Imaging Finding in Pediatric Patients after Cardiopulmonary Bypass

Abstract Objectives: This study was undertaken to estimate the incidence and burden of cerebral microhemorrhage (CM) in patients with heart disease who underwent cardiopulmonary bypass (CPB), as detected on susceptibility-weighted..

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Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass

Abstract Purpose Cardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting (CABG) surgery..

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A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension

Abstract During cardiac operations, weaning from cardiopulmonary bypass (CPB) may prove challenging as a result of superimposed acute right ventricular dysfunction in the setting of elevated pulmonary vascular resistance (PVR)...

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Assessing the depth of isoflurane anaesthesia during cardiopulmonary bypass

Abstract Introduction: Bispectral index (BIS) and monitoring of end-tidal concentration may be associated with a reduction in the incidence of awareness during volatile-based general anaesthesia. An analogue of end-tidal concentration..

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Influence of high-flow modified ultrafiltration on brain oxygenation and perfusion during surgery for children with ventricular septal defects: a pilot…

Abstract Background: Modified ultrafiltration (MUF) can be performed in infants with ventricular septal defects (VSDs) after cardiopulmonary bypass (CPB) to reduce haemodilution and its potential adverse effects. High-flow MUF might..

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Normothermic Cardiopulmonary Bypass in Patient With Waldenström’s Macroglobulinemia and Cryoglobulinemia: A Case Report

Abstract Waldenström’s macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We..

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Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations

Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..

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Neuroprotective effect of pressure-oriented flow regulation and pH-stat management in selective antegrade brain perfusion during total aortic arch repair

Abstract OBJECTIVES The aim of this study was to assess the safety and effectiveness of our selective antegrade brain perfusion (SABP) strategy, which is characterized by moderate hypothermic and low-pressure..

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Measurement of gaseous microemboli in the prime before the initiation of cardiopulmonary bypass

Abstract Introduction: The use of cardiopulmonary bypass is associated with a risk of neurocognitive deficit caused by gaseous microemboli. Flushing the empty bypass circuit with carbon dioxide, which is more..

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Hemodilution on Cardiopulmonary Bypass: Thromboelastography Patterns and Coagulation-Related Outcomes

Abstract Objective  has been associated with both  and  in studies based on  (TEG). Severe hemodilution during  (CPB) is a risk factor for morbidity in cardiac surgery. This study investigated the effects of different degrees..

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