Tags Archives: cardioplegia

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Cardioplegia: Is There a Difference? ECMO: Patient Selection Matters.

Review of cardioplegia and lecture on novel cardioplegia techniques with Del Nido. Lecture and discussion on ECMO survival and patient selection and timing of ECMO therapy initiation.  

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Should we consider beating-heart on-pump coronary artery bypass grafting over conventional cardioplegic arrest to improve postoperative outcomes in selected patients?

Abstract A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) offered superior mortality..

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Differentiating between cold agglutinins and rouleaux: a case series of seven patients

Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..

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Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model.

Abstract OBJECTIVES:  This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy phosphates during cardiac arrest..

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Celsior Versus Microplegia: Analysis of Myocardial Protection in Elective Aortic Valve Replacement

Abstract Background Previous studies have analyzed the efficacy of crystalloid , but the use of  (Genzyme Corp, Boston, MA) as a crystalloid cardioplegic solution has not been evaluated. Methods In this observational..

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Del Nido Cardioplegia in Coronary Artery Bypass Grafting Surgery: A safe, efficacious and economic alternative to St. Thomas solution; an…

Abstract Introduction: del Nido cardioplegia is a newer solution getting popular worldwide, whereas in Nepal, St. Thomas cardioplegia solution is conventionally used. There is no national recommendation on cardioplegia solutions..

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del Nido cardioplegia in adult cardiac surgery - scopes and concerns

Abstract The convenience offered by a single-dose cardioplegia strategy is the avoidance of interruption of the flow of surgery and, more importantly, a significant reduction in the cross-clamp time. del..

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Mechanisms of oxidative stress and myocardial protection during open-heart surgery

Abstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia..

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Does magnesium-supplemented cardioplegia reduce cardiac injury? A meta-analysis of randomized controlled trials

Abstract Background: Magnesium is often used to supplement cardioplegic solutions during cardiopulmonary bypass due to its cardioprotective effect during ischemia and reperfusion. The aim of this meta-analysis was to evaluate the..

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Cardioplegia in paediatric cardiac surgery: a systematic review of randomized controlled trials

OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence..

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Cardioplegia practice in paediatric cardiac surgery: a UK & Ireland survey

Abstract Introduction: Many techniques are available for cardioplegic arrest in children, but there is a lack of late phase clinical trials to guide practice. We surveyed paediatric cardiac surgeons and..

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Facilitating technologies in minimally invasive aortic valve replacement: a propensity score analysis

Abstract OBJECTIVES Minimally invasive aortic valve replacement (MIAVR) can be technically demanding and may lead to prolonged operative time. We evaluated the intraoperative and postoperative patient outcomes following implementation of..

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Investigation of Myocardial Protection During Pediatric CPB: Practical Experience in 100 Chinese Hospitals

Abstract Many measures have been proposed for myocardial protection in pediatric congenital heart surgeries, but little data is available for China. This study investigates myocardial protection strategies in pediatric cardiopulmonary..

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Sustained Total All-Region (STAR) Perfusion: An Optimized Perfusion Strategy for Norwood Reconstruction

Abstract Early iterations of the Norwood procedure used aortic cross-clamping, myocardial arrest, and, sometimes, deep hypothermic circulatory arrest. The resulting hypothermia and prolonged ischemia caused frequent cardiac, neurologic, renal, and..

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