Abstract Early iterations of the Norwood procedure used aortic cross-clamping, myocardial arrest, and, sometimes, deep hypothermic circulatory arrest. The resulting hypothermia and prolonged ischemia caused frequent cardiac, neurologic, renal, and..
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Abstract Many measures have been proposed for myocardial protection in pediatric congenital heart surgeries, but little data is available for China. This study investigates myocardial protection strategies in pediatric cardiopulmonary..
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Abstract OBJECTIVES Minimally invasive aortic valve replacement (MIAVR) can be technically demanding and may lead to prolonged operative time. We evaluated the intraoperative and postoperative patient outcomes following implementation of..
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Abstract Introduction: Many techniques are available for cardioplegic arrest in children, but there is a lack of late phase clinical trials to guide practice. We surveyed paediatric cardiac surgeons and..
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OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence..
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Abstract Background: Magnesium is often used to supplement cardioplegic solutions during cardiopulmonary bypass due to its cardioprotective effect during ischemia and reperfusion. The aim of this meta-analysis was to evaluate the..
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Abstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia..
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Abstract The convenience offered by a single-dose cardioplegia strategy is the avoidance of interruption of the flow of surgery and, more importantly, a significant reduction in the cross-clamp time. del..
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Abstract Introduction: del Nido cardioplegia is a newer solution getting popular worldwide, whereas in Nepal, St. Thomas cardioplegia solution is conventionally used. There is no national recommendation on cardioplegia solutions..
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Abstract Background Previous studies have analyzed the efficacy of crystalloid , but the use of (Genzyme Corp, Boston, MA) as a crystalloid cardioplegic solution has not been evaluated. Methods In this observational..
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Abstract OBJECTIVES: This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy phosphates during cardiac arrest..
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Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..
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Abstract A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) offered superior mortality..
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Review of cardioplegia and lecture on novel cardioplegia techniques with Del Nido. Lecture and discussion on ECMO survival and patient selection and timing of ECMO therapy initiation.
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Eric Skipper, MD lectures and discusses the various cardioplegia cocktails and why he prefers one over another.
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The de novo use of Del Nido cardioplegia in adult cardiac surgery has gained in popularity, many variations to the original Del Nido formula have come into vogue. Is this..
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The Vanderbilt Faculty team will discuss Single ventricle physiology and how this affects perfusion technique during surgical correction. Our Journal Club explores alternative techniques to long acting cardioplegia..
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Abstract Objective: The aim of this study was to evaluate outcome measures between our standard multidose cardioplegia protocol and a del Nido cardioplegia protocol in congenital heart surgery patients. Methods:..
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Abstract Objective Custodiol-HTK (Custodiol-HTK Koheler Chemie, GmbH, Bensheim, Germany) causes fluctuations in serum sodium levels, , and is associated with postoperative seizures. We investigated the influence of scavenging right atrial effluent during..
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Abstract Background: Mitochondrial permeability transition pore (mPTP) opening plays a crucial role in cell death during ischemia-reperfusion injury (IRI). Cyclosporine A (CsA) inhibits mPTP opening. This study aimed to investigate..
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Abstract Cardioplegic solutions are used in cardiac surgery to achieve controlled cardiac arrest during operations, making surgery safer. Cardioplegia can either be blood or crystalloid based, with perceived pros and..
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Abstract Background del Nido cardioplegia has been adopted for use in adult cardiac surgery, despite a lack of robust randomised evidence supporting equivalence or superiority to conventional hyperkalaemic blood cardioplegia...
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Dedicated solutions for all of the different myocardial protection methods.A wide collection of crystalloid, cold and warm blood cardioplegia systems available for delivering your myocardial protection.[pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/09/Myocardial-CPL-solutions_09294-82B_compressed.pdf" title="Myocardial CPL solutions_09294-82B_compressed"]..
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Abstract Introduction: Adenosine triphosphate - sensitive potassium (KATP) channels provide endogenous myocardial protection by coupling cell membrane potential to metabolism, as they are inhibited by ATP and open during times of..
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Abstract Introduction Minimally invasive cardiac surgery has been evolving, with the intention of reducing surgical trauma, improve cosmesis and patient satisfaction. Single dose, crystalloid cardioplegia such as Del Nido cardioplegia..
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Abstract Objectives: Cardiac surgery with cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery and aortic valve diseases. However, the myocardium sustains reperfusion injury after ischemic cardioplegic arrest...
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Abstract Background: In this prospective randomized controlled trial, we compared the standard del Nido cardioplegia solution (SDN) with the modified del Nido cardioplegia solution (MDN) in which the base solution was..
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Abstract Zafren, Ken, Raimund Lechner, Peter Paal, Hermann Brugger, Giles Peek, and Tomasz Darocha. Induced hypothermia to as cold as 3°C in humans: Forgotten cases rediscovered. High Alt Med Biol. 22:000–000, 2021...
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Abstract OBJECTIVES : To investigate Stone Heart Syndrome (SHS) as consequence of prolonged ischemic arrest in an experimental study on pigs in regards to onset of SHS and pathological changes...
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Abstract Background We investigated the myocardial protective effect of a moderate-potassium cold blood cardioplegic solution (K+, 10 mmol/L) in pediatric cardiac surgery. Methods Sixty-eight pediatric patients with congenital heart disease..
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