Tags Archives: cardiomyocytes

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Acellular Hemoglobin Impairs Cardiomyocyte Excitation-Contraction Coupling

Abstract Heart failure is a significant complication of chronic intravascular hemolysis, a condition characterized by red blood cells (RBCs) breakdown, leading to the release of acellular hemoglobin (Hb) and its..

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Adaptation mechanisms of cardiomyocytes isolated from patients with Tetralogy of Fallot to hypoxic conditions

Abstract Introduction Congenital cardiac defects disrupt circulation and oxygenation due to structural changes in the heart. Tetralogy of Fallot is the most common cyanotic congenital heart disease, accounting for 5..

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The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes

Abstract The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via mechanical and electrical junctions. Although described in some detail by light microscopy in the 19th century,..

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