New threats to effective scientific communication make it more difficult to separate science from science fiction. Patients can be harmed by misinformation or by misplaced trust; for example, patients with cancer using complementary medicine are more likely than patients not using it to refuse evidence-based therapies and have higher mortality.1 Researchers who produce objective science can no longer focus on simply disseminating the message. Now they must also defend that evidence from challenges to the validity and interpretation of their research and, at times, be proactive to ensure that unsubstantiated messages do not compete with the correct message. For instance, the unfounded, and yet persistent, beliefs linking autism with vaccination demonstrates both the health dangers of misinformation and the effort required to counteract that misinformation. The adversarial stance seems destined to decrease trust in the scientific enterprise, but the alternatives seem worse.