Pediatric

Perfusfind S.L.

Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition to having cefazolin added to the CPB circuit priming solution. Secondary aims were to determine the pharmacodynamic exposure associated with..

Perfusfind S.L.

Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of  have been associated with increased morbidity in pediatric cardiac patients. Transfusion of red blood cells, platelets, and  is necessary to combat the  associated with  and to treat . We are challenged to apply new pharmacologic, ,..

Perfusfind S.L.

Abstract The objective of this study is to establish reliable markers for mortality in children with refractory cardiogenic shock who underwent extracorporeal membrane oxygenation. A retrospective observational cohort study was performed at academic children’s hospital for forty-three consecutive pediatric patients who required veno-arterial extracorporeal membrane oxygenation (ECMO) support with refractory..

Perfusfind S.L.

OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence base. METHODS We searched MEDLINE, CENTRAL and LILACS and manually screened retrieved references and systematic reviews to identify all randomized..

Perfusfind S.L.

Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis during Dihead CPB, we compared the hemolysis caused by three different suction systems and performed a clinical study with the..

Perfusfind S.L.

Abstract Aim To assess the use of   (ECPR), compared with manual or mechanical cardiopulmonary resuscitation (CPR), for  (OHCA) and in-hospital cardiac arrest (IHCA) in adults and children. Methods The PRISMA guidelines were followed. We searched Medline, Embase, and Evidence-Based Medicine Reviews for  and  published before May 22, 2018. The population included adult and pediatric..

Perfusfind S.L.

Abstract Background Bleeding contributes to the high mortality of venovenous  membrane oxygenation (vvECMO). The development of acquired von Willebrand syndrome (AVWS) has been identified as relevant pathology during ECMO. This study was performed to determine the onset of AVWS after implantation and the recovery of  (VWF) parameters after explantation of ECMO in..

Perfusfind S.L.

CURRENTLY, MINIMALLY INVASIVE cardiac surgery (MICS) is very popular. In most cases, cardiopulmonary bypass (CPB) is used with femoral arterial cannulation, and the whole body is perfused in a retrograde fashion. However, in cases of inadequate venous drainage for the CPB, antegrade blood flow from the patient’s left ventricular cardiac..

Perfusfind S.L.

Abstract The use of minimized cardiopulmonary bypass support to reduce the side effects of extracorporeal circulation is still contradictorily discussed. This study compares perfusion operated by conventional (CCPB) and minimized (MCPB) cardiopulmonary bypass support during coronary artery bypass grafting (CABG). This study includes the data of 5164 patients treated at..

Perfusfind S.L.

Abstract OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have beneficial effects when considering the transmission of enveloped viruses. Additionally, it has the potential for fewer adverse reactions, reduced disease..