Pediatric

Perfusfind S.L.

Abstract Background: The  during  (CPB) to improve Recovery in Infants with  (NITRIC) trial, a 1320-patient, multicentre, , is aiming to improve survival free of ventilation after CPB by using nitric oxide delivered into the  of the CPB. Objective: To provide a statistical analysis plan before completion of patient recruitment and data monitoring. Final analyses for this study..

Perfusfind S.L.

Abstract  is a refractory disease caused by microbial invasion of the bone, leading to destruction of the . It is more common in children. Osteomyelitis requires long  at high cost and is associated with high rates of recurrence and disability. It can also be complicated by sepsis that, if not treated in..

Perfusfind S.L.

Abstract BACKGROUND:  Red blood cell (RBC) transfusions are used frequently in pediatric patients admitted to the intensive care unit (ICU) after cardiac surgery. To improve data-driven transfusion decision-making in the ICU, we conducted a retrospective analysis to assess the effect of RBC transfusion on cerebral and somatic regional oxygenation (rSO2)...

Perfusfind S.L.

Abstract OBJECTIVES:  Postoperative patients after congenital cardiac surgery are at high risk of fluid overload (FO), which is known to be associated with poor outcomes. “Fluid creep,” or nonresuscitation IV fluid in excess of maintenance requirement, is recognized as a modifiable factor associated with FO in the general PICU population,..

Perfusfind S.L.

Abstract Objective: To define a reference chart comparing pressure drop vs. flow generated by a set of arterial cannulae currently utilized in cardiopulmonary bypass conditions in pediatric surgery. Methods: Cannulae from two manufacturers were selected considering their design and outer and inner diameters. Cannula performance was evaluated in terms of pressure drop..

Perfusfind S.L.

Abstract Background.  Pulmonary hypertension (PH) is a common complication of congenital heart disease (CHD). With early surgical intervention, outcomes have improved over the last two decades. Persistent PH, however, may still occur following surgery. Sildenafil has been shown to be beneficial for postoperative pulmonary hypertensive crises. The role of preoperative..

Perfusfind S.L.

Abstract Background Prediction of cardiac surgery-associated acute kidney injury (CS-AKI) in pediatric patients is crucial to improve outcomes and guide clinical decision-making. This study aimed to develop a supervised machine learning (ML) model for predicting moderate to severe CS-AKI at postoperative day 2 (POD2). Methods This retrospective cohort study analyzed..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is an invasive life support technique that requires a blood pump, an artificial membrane lung, and vascular cannulae to drain de-oxygenated blood, remove carbon dioxide, oxygenate, and return it to the patient. ECMO is generally used to provide advanced and prolonged cardiopulmonary support in patients..

Perfusfind S.L.

Abstract Objective This study aimed to determine whether or not transfusion of fresh red blood cells (RBCs) reduced the incidence of new or progressive multiple organ dysfunction syndrome compared with standard-issue RBCs in pediatric patients undergoing cardiac surgery. Methods Preplanned secondary analysis of the Age of Blood in Children in..

Perfusfind S.L.

Abstract Care and outcomes for the more than 40,000 patients undergoing pediatric and congenital heart surgery in the United States annually are known to vary widely. While consensus recommendations have been published across numerous fields as one mechanism to promote a high level of care delivery across centers, it has..