Pediatric

Perfusfind S.L.

Abstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and its impact on outcomes after the Norwood procedure. METHODS Neonates undergoing the Norwood procedure from 2001 to 2022 were reviewed...

Perfusfind S.L.

Abstract Purpose The purpose of this systematic review was to identify the efficacy of cell salvage in adult and pediatric spinal surgery. Methods A comprehensive systematic review of four biomedical databases was conducted to identify study articles of interest. Articles from original studies were compiled for the composition of this..

Perfusfind S.L.

Abstract Aims Pediatric cardiac arrest is associated with high mortality and significant morbidity among survivors. International guidelines for prognostication remain limited due to small heterogeneous patient populations, variable post-return of circulation diagnostics, and insufficient long-term follow-up. Pediatric Resuscitation Prognostication and Outcomes Registry (PROGNOSE) is a Dutch nationwide, multicenter registry aiming..

Perfusfind S.L.

Abstract Poor or worsening functional status of lung transplant (LTx) candidates is a key risk factor for waitlist and post-transplant mortality. As more critically ill adults and children are listed for LTx, the use of extracorporeal membrane oxygenation (ECMO) as bridge to LTx is also increasing. Sustaining optimal functional status..

Perfusfind S.L.

Abstract The storing of dry-assembled and primed extracorporeal membrane oxygenation (ECMO) circuits is common practice and endorsed by the Extracorporeal Life Support Organization (ELSO) for up to 30 days. We conducted an anonymous survey among chief perfusionists in German neonatal and pediatric ECMO centers to identify key parameters of the..

Perfusfind S.L.

Abstract In neonates with pulmonary hypertension (PH) supported on veno-venous extracorporeal membrane oxygenation (VV-ECMO), keeping the ductus arteriosus (DA) open ensures a high cardiac output of well-oxygenated blood through the right to left (R-L) ductal shunt. After PH resolution, timely closure of the patent DA (PDA) prevents pulmonary overcirculation, systemic..

Perfusfind S.L.

Abstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size and insufficient adrenal stress response. We hypothesized that corticosteroids reduce systemic inflammatory response and improve clinical outcomes in neonates undergoing..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician expertise to compile various data from different sources within a stressful and time-sensitive environment. However, as electronic health records provide..

Perfusfind S.L.

Abstract This study aimed to describe patient characteristics, mortality, and morbidity outcomes in children at a South African extracorporeal membrane oxygenation (ECMO) center. Fifty-seven patients required ECMO from 2018 to 2023 at the Nelson Mandela Children’s Hospital in Johannesburg; eight neonates (14%), 35 infants (61.4%) 29 days–1 year, 11 (19%)..

Perfusfind S.L.

Abstract Background and Aims Innovative advancements in cardiopulmonary bypass (CPB) configurations, such as surface coating, blood filtration, and miniaturization, aim to reduce gaseous microemboli (GME) that contribute to embolic organ damage, particularly neurological dysfunction. Arterial line filters are effective in mitigating embolism risk. Neurological complications post-cardiac surgery can result from..