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POBS-Card, a new score of severe bleeding after cardiac surgery: Construction and external validation

Abstract Objective Bleeding after cardiac surgery leads to poor outcomes. The objective of the study was to build the PeriOperative Bleeding Score in Cardiac surgery (POBS-Card) to predict bleeding after..

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In vitro protamine addition for coagulation assessment using TEG 6s system during cardiopulmonary bypass: a pilot study

Abstract Objective Systemic heparinization during cardiopulmonary bypass (CPB) can significantly affect thromboelastography (TEG). This study investigated the feasibility of adding protamine in vitro to allow assessment of coagulation status using the..

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Evaluating the Use of Unfractionated Heparin with Intra-Aortic Balloon Counterpulsation

Abstract Background Evidence supporting  with unfractionated heparin (UFH) in patients with an intra-aortic balloon pump (IABP) to prevent  remains limited, while bleeding risks remain high. Monitoring heparin in this setting with anti-factor..

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Predictors of Mortality in Adults With Calcium Channel Blocker Toxicity Receiving Extra Corporeal Membrane Oxygenation Support: An Extracorporeal Life Support…

Abstract Calcium channel blocker (CCB) toxicity presents a significant mortality risk, highlighting the need for effective treatment strategies such as extracorporeal membrane oxygenation (ECMO). This study analyzes Extracorporeal Life Support..

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Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi…

Abstract Purpose: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management  algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right  ventricular injury (RVI)..

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Megalin-related mechanism of hemolysis-induced acute kidney injury and the therapeutic strategy

Abstract Hemolysis-induced acute kidney injury (AKI) is attributed to heme-mediated proximal tubule epithelial cell (PTEC) injury and tubular cast formation due to intratubular protein condensation. Megalin is a multiligand endocytic..

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Evaluation of university and training standards in clinical perfusion, an European-wide survey

Abstract OBJECTIVES Adequate theoretical and practical training of prospective clinical perfusionists is essential for maintaining clinical standards and ensuring patient safety during cardiac surgery procedures. Perfusion schools play a crucial..

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First worldwide use of the hybrid system for extracorporeal circulation in heart transplant

Abstract Background This case report documents the first worldwide use of the Hybrid System from Spectrum Medical in a heart transplant procedure, focusing on its safety and efficacy. Traditional cardiopulmonary..

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Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism: A Systematic Review of Case Reports

Abstract Amniotic fluid embolism (AFE) is an obstetric complication that can result in acute circulatory failure during and after labor. The effectiveness of extracorporeal membrane oxygenation (ECMO) in AFE patients..

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HIPEC technique in thoracic organs in advanced CA of pericardium

Usage of HIPEC techniques for the first time in thoracic organs in advanced CA of pericardium.   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well..

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Conversion technique from venovenous to venopulmonary ECMO support

We present the cannulation technique for venopulmonary extracorporeal membrane oxygenation using the ProtekDuo dual-lumen cannula in a patient who, after a bilateral orthotopic lung transplant and coronavirus disease 2019 infection,..

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Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation

Abstract Purpose: Patients receiving venoarterial extracorporeal membrane oxygenation (VA‑ECMO) frequently develop arte‑rial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets may also lead to harmful episodes of hypoxaemia...

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Perioperative extracorporeal membrane oxygenation in liver transplantation—bridge to transplantation, intraoperative salvage, and postoperative support: outcomes and predictors for survival in…

Abstract Data on perioperative extracorporeal membrane oxygenation (ECMO) in liver transplantation (LT) are scarce. ECMO has been used preoperatively, intraoperatively, and postoperatively for a variety of indications at our center...

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support [1, 2]. Yet, few data are avail-able..

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Outcome, compliance with inclusion criteria and cost of extracorporeal cardiopulmonary resuscitation (ECPR) in out-of-hospital cardiac arrest: A retrospective cohort study

Abstract Introduction The primary aim was to describe the outcome, the compliance with inclusion criteria and the characteristics of patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest..

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Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL…

Abstract Extracorporeal membrane oxygenation (ECMO) is a high-risk and low-volume life support with increasing clinical study. However, heterogenous outcome definitions impede data assimilation into evidence to guide practice. The Academic..

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Heart Transplantation and Left Ventricular Assist Devices: Long-Term Prognosis and Effects on Mental Health

Abstract Heart transplantation and left ventricular assist devices (LVADs) have emerged as crucial interventions for end-stage heart failure, dramatically improving patient outcomes. This narrative review examines their historical context, indications,..

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Extracorporeal cardiopulmonary resuscitation for pediatric out-of-hospital cardiac arrest: A review of the Extracorporeal Life Support Organization Registry

Abstract Aims Current data are insufficient for the leading resuscitation societies to advise on the use of extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric out-of-hospital cardiac arrest (OHCA). The aim of..

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Temporal trends in organ donation among cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation

Abstract Aims This study explores the evolution of organ donation from patients treated with extracorporeal-cardiopulmonary-resuscitation (ECPR) for refractory out-of-hospital-cardiac-arrest (OHCA) and evaluates the public health benefits of a mature ECPR..

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The Relationship Between Transfusion in Cardiac Surgery Patients and Adverse Outcomes

Abstract Objectives To understand if red blood cell (RBC) transfusions are independently associated with a risk of mortality, prolonged , or infectious, cardiac, or renal morbid outcomes. Design A retrospective review...

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Cardiopulmonary bypass and VA‑ECMO induced immune dysfunction: common features and differences, a narrative review

Abstract Cardiopulmonary bypass (CPB) and veno-arterial extracorporeal membrane oxygenation are critical tools in contemporary cardiac surgery and intensive care, respectively. While these techniques share similar components, their application contexts differ,..

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Aortic Dissection in a Neonate Receiving Extracorporeal Life Support Therapy: A Case Report

Abstract Extracorporeal life support (ECLS) therapy is increasingly being used to support children with refractory cardiorespiratory failure, but its use is occasionally associated with complications. Neonatal aortic dissection in association..

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Comparison of microbial growth on primed extracorporeal membrane oxygenation circuits in varying environments using different priming solutions

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a life support device for patients with severe heart and/or lung failure. Emergency situations require immediate ECMO response. Primed circuits have become a..

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ECMO: more than just a bridge over troubled waters?

Abstract Extracorporeal membrane oxygenation (ECMO) is used in severe cardiorespiratory failure refractory to conventional management, often as a bridge to recovery, long-term support, or transplant. However, some patients might not..

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Proteomics of the heart

Abstract Mass spectrometry-based proteomics is a sophisticated identification tool specializing in portraying protein dynamics at a molecular level. Proteomics provides biologists with a snapshot of context-dependent protein and proteoform expression,..

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Computational fluid dynamics in cardiac surgery and perfusion: A review

Abstract Cardiovascular diseases persist as a leading cause of mortality and morbidity, despite significant advances in diagnostic and surgical approaches. Computational Fluid Dynamics (CFD) represents a branch of fluid mechanics..

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Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Abstract Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of..

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Continuing ECMO with no possible transition to recovery or transplant

Abstract Controversy has emerged around how to treat patients who were placed on extracorporeal membrane oxygenation (ECMO) expecting recovery, organ transplant, or durable device, but who can no longer be..

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Perfusion and pulsatile pressure: their relationship with target organ damage in the African-PREDICT study

Abstract Background Hypertension is the leading risk factor for subclinical target-organ damage (TOD) and cardiovascular disease (CVD). Little is known about the relationship between different pressure measures and subclinical TOD,..

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Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting…

Abstract Objectives To compare the incidence of delirium and early (at 1 week)  (POCD) between propofol-based  (TIVA) and volatile anesthesia with  in adult patients undergoing elective  (CABG) with  (CPB). Design This was a prospective randomized..

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