Abstract Study Design Retrospective study. Purpose To investigate the risk factors for allogeneic red blood cell (RBC) transfusion in adult spinal deformity (ASD) surgery. Overview of Literature Studies have not..
Read MoreAbstract The complement system is a set of over 50 proteins that constitutes an essential part of the innate immune system. Complement system activation involves an organized proteolytic cascade. Overactivation..
Read MoreAbstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support. Yet, few data are avail-able to support..
Read MoreAbstract THE 2023 International Society for Heart and Lung Transplantation (ISHLT) guidelines for mechanical circulatory support (MCS) supersede the 2013 guidelines published a decade ago, incorporating substantial developments in device technology and..
Read MoreAbstract Introduction: Amniotic fluid embolism (AFE) is a catastrophic complication of pregnancy with high mortality rate. It is an inflammatory response leading to cardiovascular collapse. We present a case of successful..
Read MoreAbstract Heparin resistance (HR) is observed before cardiopulmonary bypass (CPB), despite with normal antithrombin III (AT-III) levels. The relationships between preoperative AT-III activity and activated clotting time (ACT) after the..
Read MoreAbstract Background: Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting via a multi-fenestrated..
Read MoreAbstract Sepsis is a dysregulated host response to infection responsible for life-threatening organ dysfunction.1 Along with early antimicrobial administration and source control, correction of hemodynamic derangements is a crucial aspect of..
Read MoreProf. Elio Carvalho é Biomédico, Microbiologista e Perfusionista pela Unicamp, CLAP e SBCEC. É perfusionista do Hospital de Clínicas da Unicamp e Coordenador do Curso da Unicamp de Perfusionistas. É..
Read MoreAbstract Science communication is a core skill for undergraduate science students to acquire in preparation for their future careers, but studies show that this skill is underdeveloped in science graduates...
Read MoreAbstract Antithrombin (AT) deficiency in the extracorporeal circulation during cardiac surgery leads to uncontrolled inflammation and vascular damage in patients. AT levels decrease in sepsis, major trauma, extracorporeal membrane oxygenation,..
Read MoreAbstract Monitoring the metabolic cost or oxygen consumption associated with rest and exercise is crucial to understanding the impact of disease or physical training on the health of individuals. Traditionally,..
Read MoreAbstract Importance Liberal oxygen (hyperoxia) is commonly administered to patients during surgery, and oxygenation is known to impact mechanisms of perioperative organ injury. Objective To evaluate the effect of intraoperative hyperoxia compared..
Read MoreAbstract Objectives Cardiac surgery associated-acute kidney injury is a common and serious postoperative complication of cardiac surgery, which is associated with increased postoperative morbidity and mortality. This study aimed to..
Read MoreAbstract Cardiac surgery is a distinctive surgical discipline that often necessitates the use of cardiopulmonary bypass (CPB) and full anticoagulation intraoperatively, along with varying levels of antithrombotic treatments both before..
Read MoreAbstract Background: Patient selection for extracorporeal membrane oxygenation (ECMO) support is complex and associated with variability between clinicians. Disparities exist in ECMO use, with lower utilization in patients who are female,..
Read MoreAbstract Background Acute kidney injury (AKI) frequently occurs as a complication of cardiac surgery and cardiopulmonary bypass (CPB). Its prevalence and severity are determined by various preoperative and intraoperative factors...
Read MoreAbstract Introduction: In remote hospital settings, providing timely and effective extracorporeal cardiopulmonary resuscitation (ECPR) is challenging due to infrastructure limitations and accessibility issues. We are highlighting the importance of grab-and-go ECPR..
Read MoreAbstract Background Communication failures contribute to quality gaps and may lead to serious safety events (SSEs) in the operating room (OR). Our perioperative services team experienced an increased rate of..
Read MoreAbstract Background: A body mass index (BMI) ≥ 35 kg/m² is traditionally a contraindication to extracorporeal support. We evaluated outcomes and quality of life (QoL) associated with veno-venous extracorporeal membrane oxygenation (VV-ECMO)..
Read MoreAbstract Introduction: Although outcomes of post-cardiotomy extracorporeal membrane oxygenation (ECMO) are well studied1, the outcomes of patients bridged to cardiac surgery with ECMO are less well understood. We undertook this study..
Read MoreAbstract Background Critical care of patients on extracorporeal membrane oxygenation (ECMO) with acute brain injury (ABI)is notable for a lack of high‑quality clinical evidence. Here, we offer guidelines for neurological..
Read MoreAbstract Objectives To assess microvascular reactivity during a skin thermal challenge early post-cardiac surgery and its association with outcomes. Design Noninvasive physiological study. Setting Thirty-five-bed department of intensive care. Participants..
Read MoreAbstract Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study..
Read MoreAbstract Introduction This study aimed to examine the educational challenges faced by perfusionists in Japan. Although Japan has over 400 cardiovascular surgery centers, it performs fewer surgeries than by countries..
Read MoreAbstract The optimal dosing strategy of antimicrobial agents in critically ill patients receiving extracorporeal membrane oxygenation (ECMO) is unknown. We conducted comprehensive review of existing literature on effect of ECMO..
Read MoreAbstract BACKGROUND Cardiac surgery involving cardiopulmonary bypass induces a significant systemic inflammatory response, contributing to various postoperative complications, including pulmonary dysfunction, myocardial and kidney injuries. OBJECTIVE To investigate the effect..
Read MoreAbstract Background Central venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly employed strategy to support patients in refractory postcardiotomy cardiogenic shock (RPCS). This support can be provided using either indirect..
Read MoreAbstract Study objective The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients..
Read MoreAbstract Purpose: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right ventricular injury (RVI)..
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