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“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract IMPORTANCE:  “Awake” cannulation for venovenous extracorporeal membrane oxygenation (ECMO), where patients remain spontaneously breathing without invasive mechanical ventilation during the cannulation procedure, may reduce lung injury from positive pressure..

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Cardiac Function Decline After General Anesthesia and Cardiac Catheterization in Pediatric Cardiac Transplant Recipients

Abstract Background Pediatric cardiac transplant recipients undergo elective cardiac catheterization and endomyocardial biopsy (CC/EMB) for graft dysfunction surveillance often facilitated by general anesthesia (GA). GA and positive pressure ventilation (PPV)..

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Heparin treatment is associated with a delayed diagnosis of Alzheimer’s dementia in electronic health records from two large United States…

Abstract Recent studies suggest that heparan sulfate proteoglycans (HSPG) contribute to the predisposition to, protection from, and potential treatment and prevention of Alzheimer’s disease (AD). Here, we used electronic health..

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CIRBP Aggravation of Cardiac Fibrosis after Myocardial Infarction during ECMO Assistance

Abstract Background: Cold-induced RNA binding protein (CIRBP) is widely involved in critical physiological processes of myocardial fibrosis (MF), a crucial mechanism of cardiac insufficiency in myocardial infarction (MI). However, whether CIRBP..

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Systemic Inflammatory Responses in ECMO-Treated Patients: A Systematic Reviews and Meta-Analysis

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is associated with significant inflammatory reactions that can impact patient outcomes. This meta-analysis aimed to evaluate the impact of ECMO on the functional ability of..

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Exploring Intraoperative Cognitive Biases in Cardiac Surgery Teams

Abstract This study focuses on understanding the influence of cognitive biases in the intra-operative decision-making process within cardiac surgery teams, recognizing the complexity and high-stakes nature of such environments. We..

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Association Between Individualized Versus Conventional Blood Glucose Thresholds and Acute Kidney Injury After Cardiac Surgery: A Retrospective Observational Study

Abstract Objectives This study was designed to compare individualized and conventional hyperglycemic thresholds for the risk of  (AKI) after cardiac surgery. Design This was an observational study. Setting The study took..

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Hemodynamic Effect of Hydroxocobalamin During Extracorporeal Membrane Oxygenation

Abstract Background: Hydroxocobalamin increases systemic blood pressure through nitric oxide pathway suppression. However, its effects on hypotension during extracorporeal membrane oxygenation (ECMO) are unknown. The objective of this study was to..

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Impact of Blood Sampling Methods on Blood Loss and Transfusion After Pediatric Cardiac Surgery: An Observational Study

Abstract Objectives The aims of this study were to assess the impact of the closed-loop sampling method on  and the need for  in pediatric patients following cardiac surgery. Design Retrospective observational study...

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Transmitral Doppler flow reflecting elevated pulsatility index in a HeartMate III assist device Get access Arrow

Abstract A 70-year-old patient with idiopathic dilated cardiomyopathy underwent implantation of a HeartMate III left ventricular assist device (LVAD) at INTERMACS IV. Postoperatively, right ventricular (RV) failure was managed with..

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Evaluating the Capabilities of Generative AI Tools in Understanding Medical Papers: Qualitative Study

Abstract Background: Reading medical papers is a challenging and time-consuming task for doctors, especially when the papers are long and complex. A tool that can help doctors efficiently process and..

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Heart rhythm at hospital admission: A factor for survival and neurological outcome among ECPR recipients?

Abstract Background The initial rhythm is a known predictor of survival in extracorporeal cardiopulmonary resuscitation (ECPR) patients. However, the effect of the rhythm at hospital admission on outcomes in these..

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The 10 Commandments of Less Invasive CABG: How to Increase Adoption

Abstract Introduction Coronary artery bypass grafting (CABG) is one of the most performed operations worldwide. However, CABG is often as invasive today as it was 50 years ago. Less invasive..

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The Impact of Cannulation Sites on Post-Cardiotomy ECMO Outcomes

Abstract Introduction: Although post-cardiotomy extracorporeal membrane oxygenation (ECMO) is associated with high mortality1, the impact of cannulation site is poorly understood. Methods: We conducted a retrospective review of our post-cardiotomy veno-arterial ECMO..

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“Ping-pong” in the heart: a case report and literature review

Abstract Background Ball thrombus is rare and life-threatening. The correct diagnosis and timely management are key to improving patient prognosis. Here, we present a case report and literature review of..

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Impact of intraoperative blood products, fluid administration, and persistent hypothermia on bleeding leading to reexploration after cardiac surgery

Abstract Objective Risk factors for severe postoperative bleeding after cardiac surgery remain multiple and incompletely elucidated. We evaluated the impact of intraoperative blood product transfusions, intravenous fluid administration, and persistently..

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What Are We Transfusing? Evaluating the Quality and Clinical Utility of Intraoperatively Salvaged Red Blood Cells in Spinal Deformity Surgery:…

Abstract BACKGROUND AND OBJECTIVES:  Intraoperative red blood cell (RBC) salvage is frequently used in contemporary spine surgery, despite clinical concern in its efficacy as a surrogate for blood-banked allogeneic packed..

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Standard versus High Cardiopulmonary Bypass Flow Rate: A Randomized Controlled Subtrial Comparing Brain Injury Biomarker Release

Abstract Objectives To compare brain injury biomarker release levels between two different cardiopulmonary bypass (CPB) flow rates in elective cardiac surgery and to explore differences in postoperative delirium between groups..

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Comparison of 4% Albumin and Ringer's Acetate on Hemodynamics in On-pump Cardiac Surgery: An Exploratory Analysis of a Randomized Clinical…

Abstract Objectives Compare hemodynamics between 4% albumin and Ringer's acetate. Design Exploratory analysis of the double-blind randomized ALBumin In Cardiac Surgery trial. Setting Single-center study in Helsinki University Hospital. Participants..

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Minimally Invasive Approach versus Sternotomy for Cardiac Surgery in Jehovah's Witness Patients

Abstract Objective To evaluate the outcomes of minimally invasive cardiac surgery (MICS) compared with the sternotomy approach for Jehovah's Witness (JW) patients who cannot receive blood transfusions Design This was..

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Intraoperative cell salvage reduces postoperative allogeneic blood transfusion and shortens off-bed time in simultaneous bilateral total hip arthroplasty: a single-center…

Abstract Background Simultaneous bilateral total hip arthroplasty (SI-THA) results in more blood loss and a greater need for postoperative allogeneic blood transfusion (ABT). Previous studies have reported that multimodal patient..

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Does Timing Matter? The Effect of Intensive Care Unit Arrival Timing on Elective Cardiac Surgery

Abstract Background Due to staffing changes at scheduled intervals and decreases in essential staff in the evenings, late intensive care unit (ICU) arrivals may be at risk for suboptimal outcomes...

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Blood Pressure Management for Hypotensive Patients in Intensive Care and Perioperative Cardiovascular Settings

Abstract Blood pressure is a critical physiological parameter, particularly in the context of cardiac intensive care and perioperative settings. As a primary indicator of organ perfusion, the maintenance of adequate..

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Huaxi integrated blood management reduces the red blood cell transfusion for on-pump cardiac surgery: A quasi-experimental study

Abstract Objective As many as half of patients undergoing on-pump cardiac surgery require red blood cell transfusion, emphasizing the need for effective strategies that can reduce this need. We conducted..

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Cardiopulmonary bypass and VA-ECMO induced immune dysfunction: common features and differences, a narrative review

Abstract Cardiopulmonary bypass (CPB) and veno-arterial extracorporeal membrane oxygenation are critical tools in contemporary cardiac surgery and intensive care, respectively. While these techniques share similar components, their application contexts differ,..

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Aortic versus axillary artery cannulation for hemiarch replacement: single-centre real-world experience

Abstract Background Aortic arch disease is a major cause of acute dissections. Surgical replacement is the current curative treatment for aortic arch disease. While traditional aortic cannulation ensures lower body..

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Case report: Woven-like coronary arteries in a patient with polycythemia vera

Abstract Background Woven coronary artery (WCA) is a rare and underdiagnosed congenital anomaly that involves multiple thin and tortuous epicardial arterial conduits reassembling distally into a single lumen. Recanalized thrombus..

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Non-circulatory arrest aortic arch replacement

The definitive management of combined aortic arch and descending aortic pathologies such as aneurysms and dissections is either a single or staged operation associated with high morbidity and mortality. Stroke,..

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A dimensional analysis of experienced intensive care unit nurses' clinical decision-making for bleeding after cardiac surgery

Abstract Bleeding following cardiac surgery is common and serious, yet a gap persists in understanding how experienced intensive care nurses identify and respond to such complications. Aim To describe the..

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Peritoneal Infusion of Oxygen Microbubbles Alters the Metabolomic Profile of the Lung and Spleen in Acute Hypoxic Exposure

Abstract Administration of oxygen microbubbles (OMBs) has been shown to increase oxygen and decrease carbon dioxide in systemic circulation, as well as reduce lung inflammation and promote survival in preclinical..

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