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Antepartum Extracorporeal Life Support: A Viable Way to Improve Fetal Outcomes

Abstract Extracorporeal life support (ECLS) has become increasingly common in the United States to manage refractory cardiopulmonary failure and has been used in complex populations including pregnant women. Application of..

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Efficacy and safety of prone positioning in patients undergoing extracorporeal membrane oxygenation (ECMO): A systematic review and meta-analysis

Abstract Background Acute respiratory distress syndrome (ARDS) is a severe lung condition characterized by diffuse alveolar damage and hypoxemia. Venovenous extracorporeal membrane oxygenation (vv-ECMO) supports gas exchange and reduces ventilator-induced..

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How unprofessional behaviours between healthcare staff threaten patient care and safety

Abstract Introduction Unprofessional behaviors (UB) such as bullying and incivility among healthcare staff are a significant and pervasive issue, impacting staff wellbeing, and patient safety and experiences of care. Despite..

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Optimal reperfusion strategy in acute high-risk pulmonary embolism requiring extracorporeal membrane oxygenation support: a systematic review and meta-analysis

Abstract Background The optimal pulmonary revascularisation strategy in high-risk pulmonary embolism (PE) requiring implantation of extracorporeal membrane oxygenation (ECMO) remains controversial. Methods We conducted a systematic review and meta-analysis of..

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Long-Term Health-Related Quality of Life in Survivors of Extracorporeal Cardiopulmonary Resuscitation Compared to Conventional Cardiopulmonary Resuscitation- A cohort study using…

Abstract Aim To compare the long-term Health-Related Quality of Life (HRQoL) between patients receiving extracorporeal cardiopulmonary resuscitation (ECPR) and conventional cardiopulmonary resuscitation (CCPR) for out-of-hospital cardiac arrest (OHCA). Methods and..

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2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society…

Abstract Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and..

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Scrutinizing the Role of Venoarterial Extracorporeal Membrane Oxygenation: Has Clinical Practice Outpaced the Evidence?

Abstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) for temporary mechanical circulatory support in various clinical scenarios has been increasing consistently, despite the lack of sufficient evidence regarding its..

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Management of high-risk acute pulmonary embolism: an emulated target trial analysis

Abstract Background: High‑risk acute pulmonary embolism (PE) is a life‑threatening condition necessitating hemody‑namic stabilization and rapid restoration of pulmonary perfusion. In this context, evidence regarding the benefit ofadvanced circulatory support..

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Guidelines for the Use of 100% Oxygen on Ventilator and Cardiopulmonary Bypass: Balancing Safety and Harm

Introduction Oxygen is vital to life and a central element of cardiopulmonary support. During cardiac surgery—whether on mechanical ventilation or cardiopulmonary bypass (CPB)—100% oxygen is often used out of tradition..

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Case Report: Oxygenator Burst During Minimally Invasive Coronary Artery Bypass Grafting (CABG) – A Critical Perfusion Incident

Abstract This case report discusses a rare and critical perfusion accident during a minimally invasive coronary artery bypass grafting (CAGB) procedure, where a Eurosets Skipper oxygenator burst 3 minutes after..

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ECMO Transport: Moving Critically Ill Patients Safely

Introduction Extracorporeal Membrane Oxygenation (ECMO) is a life-saving intervention for patients with severe cardiac and respiratory failure. However, the need for specialized ECMO care often necessitates the transport of critically..

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ECMO for Refractory Cardiogenic Shock: When Is It the Right Choice?

Introduction Refractory cardiogenic shock (RCS) is a life-threatening condition where the heart fails to supply adequate blood flow to the body's organs, despite maximal medical therapy. It is a major..

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The Clinical Relevance of Carbon Dioxide Management During Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation.

Abstract Background: Management of arterial carbon dioxide tension (PaCO₂) during extracorporeal circulation is critical to maintaining physiological stability. Both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) significantly alter natural..

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Management of Patients with Renal Failure on Cardiopulmonary Bypass

Abstract Renal failure presents a significant challenge in patients undergoing cardiopulmonary bypass (CPB), as they are at high risk for acute kidney injury (AKI), electrolyte imbalances, and fluid overload. The..

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Ethical Issues in Normothermic Regional Perfusion in Controlled Organ Donation After Determination of Death by Circulatory Criteria: A Scoping Review

Abstract Normothermic regional perfusion (NRP) is a surgical technique that can improve the quality and number of organs recovered for donation after the determination of death by circulatory criteria. Despite..

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Hemoadsorption in the Management of Septic Shock: A Systematic Review and Meta-Analysis

Abstract Background/Objectives: Septic shock remains a significant clinical challenge with consistently high mortality rates. Recent investigations have focused on the efficacy of CytoSorb® (CytoSorbents Corporation, Monmouth Junction, NJ, USA), an extracorporeal..

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Racial and Sex Disparities in Incidence, Risk Factors, and Outcomes of Neonatal Extracorporeal Life Support in the United States

Abstract The impact of race on extracorporeal life support (ECLS) availability, morbidity, and mortality remains poorly defined. We sought to define the impact of race/ethnicity, sex, and location on ECLS..

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A Novel, Interpretable Machine Learning Model to Predict Neurological Outcomes Following Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: We used machine learning models incorporating rich electronic medical record (EMR) data to predict  neurological outcomes after venoarterial extracorporeal membrane oxygenation (VA‑ECMO).   Methods: This was a retrospective..

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Continuous Kidney Replacement Therapies: Core Curriculum 2025

Abstract Critically ill patients that require kidney replacement therapy (KRT) are among the most ill and complex patients routinely encountered in the intensive care unit (ICU). Continuous KRT (CKRT) is..

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Extracorporeal membrane oxygenation after lung transplant: An ELSO registry analysis

Abstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded and is now widely applied to perioperative care in lung transplant. Respiratory failure after lung transplant is a clinical..

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Quantum Heater Cooler

  Sistema de intercambio de calor cuya principal característica es que en lugar de agua utiliza glicol como fluido, evitando la aparición de microorganismos en el sistema como la Mycrobacterium..

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Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial

Abstract Background The impact of intra-aortic balloon pump (IABP) on survival and successful bridging to heart replacement therapies (HRT) in patients with heart failure–cardiogenic shock (HF-CS) remains unclear. Objectives The..

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Evaluation of Plasma Biomarkers to Understand the Biology and Heterogeneity of Treatment Effect in Lower Tidal Volume Ventilation Facilitated by…

Abstract OBJECTIVES:  In patients with acute hypoxemic respiratory failure (AHRF), the use of lower tidal volume ventilation facilitated by veno-venous extracorporeal CO2 removal (vv-ECCO2R) does not improve clinical outcomes. The primary..

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A Retrospective Cohort Study of the Role of Palliative Care Consultation for Patients on Extracorporeal Membrane Oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) serves as a critical intervention for patients with severe cardiac and pulmonary dysfunction. Given the high rates of mortality and morbidity, as well as..

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Left Ventricular Unloading Is Associated With Lower Mortality in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the left ventricle. This study aimed to..

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Differential Venous Drainage Mimicking Differential Oxygenation in Patients on Extracorporeal Life Support

Abstract This report presents a case series that introduces differential venous drainage (DVD) as an underrated complication arising from the hemodynamic impact of the extracorporeal life support (ECLS) circuit on..

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American Society of ExtraCorporeal Technology Standards and Guidelines for Pediatric and Congenital Perfusion Practice

Abstract The American Society of ExtraCorporeal Technology (AmSECT) has created the following document based on clinical evidence and currently accepted perfusion practices. Perfusionists are allied healthcare professionals formally trained and..

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Neonatal venoarterial extracorporeal membrane oxygenation cannulation technique

Peripheral cannulation for initiation of neonatal venoarterial extracorporeal membrane oxygenation is an essential technical skill in the armamentarium of every congenital cardiac surgeon and is necessary for the care of..

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Inflammatory Response and Inflammatory Mediators in Cardiopulmonary Bypass: Management Strategies

Introduction Cardiopulmonary bypass (CPB) is a life-saving technology used in cardiac surgery; however, it triggers a systemic inflammatory response (SIRS) due to blood contact with non-endothelial surfaces, ischemia-reperfusion injury, and..

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Pump‐controlled retrograde trial off extracorporeal membrane oxygenation

Venoarterial extracorporeal membrane oxygenation weaning strategies are not standardized. When dealing with patients with complex physiologies and borderline haemodynamics, it is prudent to have a fail-safe method of approaching decannulation..

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