Home

thumbnail
0 comment

Redefining ECMO cannulation: A case for TEE-guided VP ECMO and flotation catheter

Abstract Venopulmonary ECMO (VP ECMO) is an advanced support strategy for patients with severe respiratory failure and right ventricular (RV) dysfunction, providing pulmonary protection by oxygenating blood and unloading the..

Read More
thumbnail
0 comment

Effect of cardiopulmonary bypass on late-onset hyperlactatemia after pediatric cardiac surgery

Abstract Background: This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.Methods: One hundred fifty-nine ventricular septal defect..

Read More
thumbnail
0 comment

Trauma-related psychopathologies after extracorporeal membrane oxygenation support: A systematic review and meta-analysis

Abstract Extracorporeal Membrane Oxygenation (ECMO) use is associated with substantial psychiatric morbidity in patients and their families. This systematic review and meta-analysis quantifies the prevalence of post-traumatic stress disorder (PTSD),..

Read More
thumbnail
0 comment

Performance Comparison of Centered and Tilted Blunt and Lighthouse Tip Cannulae for Drainage in Extracorporeal Life Support

Abstract Introduction Extracorporeal membrane oxygenation is a lifesaving treatment for patients with refractory acute respiratory, circulatory, or combined cardiopulmonary failure. The patient is cannulated with one or two cannulae for..

Read More
thumbnail
0 comment

Prolonged Use of Extracorporeal Membrane Oxygenators for COVID-19–Associated Acute Respiratory Distress Syndrome: A Retrospective Analysis

Abstract Whether an anticoagulation strategy combining bivalirudin and aspirin during extracorporeal membrane oxygenation (ECMO) would prolong oxygenator use is unknown. No clear data exist on oxygenator life span during prolonged..

Read More
thumbnail
0 comment

Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial

Abstract Background The impact of intra-aortic balloon pump (IABP) on survival and successful bridging to heart replacement therapies (HRT) in patients with heart failure–cardiogenic shock (HF-CS) remains unclear. Objectives The..

Read More
thumbnail
0 comment

Cerebral Inflammation in an Animal Ischemia–Reperfusion Model Comparing Histidine-Tryptophan-α-Ketoglutarate and Del Nido Cardioplegia

Abstract Brain injury and cerebral inflammation are frequent complications following cardiopulmonary bypass (CPB) resulting in neurocognitive dysfunction, encephalopathy, or stroke. We compared cerebral inflammation induced by del Nido and histidine-tryptophan-α-ketoglutarate..

Read More
thumbnail
0 comment

Branch-first technique with continuous perfusion in aortic arch repair—our initial experience

Abstract The branch-first technique (BFT) for aortic arch replacement eliminates deep hypothermia and global circulatory arrest, reducing cardiopulmonary bypass and ischemic times. We present our initial experience with BFT in..

Read More
thumbnail
0 comment

Minimally invasive cardiac surgery in congenital heart diseases: the new horizon

Abstract Introduction Sternotomy has been the most common approach for the correction of congenital cardiac defects, and questions arise surrounding the safety, feasibility, and cost-effectiveness of implementing minimally invasive techniques..

Read More
thumbnail
0 comment

Outcomes after lung transplantation performed using elective cardiopulmonary bypass: A single-center experience

Abstract Background There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation...

Read More
thumbnail
0 comment

Interplay between platelet and T lymphocyte after coronary artery bypass grafting (CABG): Evidence for platelet mediated post-CABG immunomodulation

Abstract Background On-pump coronary artery bypass grafting (CABG) triggers inflammatory responses as a result of surgical stress and extracorporeal circulation, which affect platelet and leukocyte activation while enhancing their intimate..

Read More
thumbnail
0 comment

Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease

Abstract Background Congenital heart disease is the most common neonatal congenital condition. Surgery is often necessary. Patients with congenital heart disease are potentially exposed to red cell transfusion preoperatively, intraoperatively..

Read More
thumbnail
0 comment

Impact of Different Sweep Gas Flow Rates on Respiratory Alkalosis and Cerebral Oxygenation during Cardiopulmonary Bypass

Abstract There is no consensus on the ideal sweep gas flow volume for achieving targeted blood partial gas pressures during cardiopulmonary bypass (CPB). The sweep gas flow rate is one..

Read More
thumbnail
0 comment

Successful Management of a Penetrating Cardiac Injury by Date Palm Thorn: A Case Report

Abstract Penetrating cardiac injury in children is a life-threatening emergency. The initial reaction of the witness and medical team management plays a crucial role in survival. We are reporting a..

Read More
thumbnail
0 comment

Effect of Ascorbic Acid on the Incidence of Postoperative Delirium Among Elderly Patients Undergoing Cardiovascular Surgery: A Pilot Study

Abstract Background: Ascorbic acid is a strong antioxidant that prevents postoperative delirium by inhibiting reactive oxygen species production. This pilot study was designed to investigate the prevalence of postoperative delirium among..

Read More
thumbnail
0 comment

Persistent Renal Hypoxia and Histologic Changes at 4 Weeks after Cardiopulmonary Bypass in Sheep

Abstract Background:  The sustained renal effects of exposure to cardiopulmonary bypass are unknown. This study aimed to test whether cardiopulmonary bypass (CPB) is associated with sustained renal tissue hypoxia and..

Read More
thumbnail
0 comment

A Practical Guide to Biostatistics Used in the Journal of Intensive Care Medicine

Abstract Introduction Biostatistics is an increasing focus in both the United States Medical Licensing exams (USMLE) and medical school curricula. Nonetheless, literature has documented that it is poorly understood among..

Read More
thumbnail
0 comment

Intraoperative Hemolysis Monitoring by Real-time Point-of-care in Patients Undergoing Cardiopulmonary Bypass in Cardiac Surgery: A Single-centre Prospective Observational Study

Abstract Objective Hemolysis is a complication in surgical procedures requiring cardiopulmonary bypass (CPB). The primary aim of this study was to evaluate the effectiveness of the point-of-care device Hemcheck Helge..

Read More
thumbnail
0 comment

Goal-directed Perfusion to Reduce Acute Kidney Injury After Pediatric Cardiac Operation

Abstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..

Read More
thumbnail
0 comment

Real-time blood gas management: evaluating quantum perfusion system’s accuracy against a standard blood gas analysis in CPB

Abstract Background Continuous blood gas monitoring (CBGM) during cardiopulmonary bypass (CPB) is essential for maintaining optimal patient outcomes, enabling rapid responses to critical fluctuations in blood gas parameters. This non-inferiority..

Read More
thumbnail
0 comment

Outcomes of Neonatal Cardiac Surgery: A European Congenital Heart Surgeons Association Study

Abstract Background We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA). Methods All patients ≤30 days of life undergoing a cardiac..

Read More
thumbnail
0 comment

Understanding what leaders can do to facilitate healthcare workers’ feeling valued: improving our knowledge of the strongest burnout mitigator

Abstract Aim Feeling valued is a striking mitigator of burnout yet how to facilitate healthcare workers (HCWs) feeling valued has not been adequately studied. This study discovered factors relating to HCWs..

Read More
thumbnail
0 comment

Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery

Abstract Importance  Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate..

Read More
thumbnail
0 comment

Exploring the Role of Immersive Virtual Reality Simulation in Health Professions Education: Thematic Analysis

Abstract Background: Although technology is rapidly advancing in immersive virtual reality (VR) simulation, there is a paucity of literature to guide its implementation into health professions education, and there are..

Read More
thumbnail
0 comment

Diagnosing Nosocomial Infections During Pediatric Extracorporeal Membrane Oxygenation

Abstract Nosocomial infections are one of the most frequent complications of extracorporeal membrane oxygenation (ECMO) and are associated with increased mortality (). Bloodstream infections present a particular problem because of..

Read More
thumbnail
0 comment

Enhancing the quality of surgical care through improved patient handover processes

Abstract Surgical handover remains a high-risk process with no gold standard for practice despite 20 years of available guidance. Variability in practice is common, and poorly performed handover poses significant,..

Read More
thumbnail
0 comment

Cardiac myxoma: a comprehensive review

Abstract Heart tumours are a diverse group of tumours that may present with symptoms or be discovered incidentally when a patient is being evaluated for a physical or seemingly unrelated..

Read More
thumbnail
0 comment

Adjunctive Fresh Frozen Plasma Versus Adjunctive Cryoprecipitate in Cardiac Surgery Patients Receiving Platelets for Perioperative Bleeding

Abstract Objective(s) This study was designed to assess the relative association between adjunctive fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in cardiac surgery patients receiving platelets..

Read More
thumbnail
0 comment

Substrate Enhancement in Cardioplegia: Current Concepts and Future Directions

Introduction Myocardial protection during cardiac surgery is a critical determinant of patient outcomes. Traditional cardioplegia techniques primarily aim to arrest the heart, reduce metabolic demand, and preserve myocardial viability (Buckberg,..

Read More
thumbnail
0 comment

The Air-Blood Interface During Cardiopulmonary Bypass: Mechanisms and Clinical Implications

Introduction: Cardiopulmonary bypass, a cornerstone of modern cardiac surgery, temporarily diverts blood away from the heart and lungs, allowing for surgical intervention in a controlled environment. During CPB, blood is..

Read More