Abstract Background: Dosing albumin to normalize colloid osmotic pressure is an underutilized strategy within the application of cardiopulmonary bypass. The negative sequelae of third-spacing and edema post-bypass are well known..
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Abstract Objective: To evaluate inflammatory biomarkers and lipidomic profiles in tracheal aspirates (TA) of infants with congenital heart disease (CHD), by pulmonary blood flow (Qp) high/low grouping at the time..
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Abstract Background: Hemofiltration during pediatric cardiopulmonary bypass (CPB) is essential to mitigate hemodilution, inflammatory responses, and postoperative complications. Conventional ultrafiltration (CUF) is widely practiced, but novel methods such as subzero..
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Abstract Introduction del Nido cardioplegia had not been commercially available in the United Kingdom prior to the DESTINY trial, a multi-centre individually randomised controlled trial to evaluate whether del Nido..
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Abstract Introduction: The global prevalence of morbid obesity is increasing, presenting challenges in cardiac surgery. Morbid obesity (body mass index ≥40 kg/m2) is associated with a high burden of cardiometabolic comorbidities..
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Abstract Objectives To identify a critical cardiopulmonary bypass (CPB) duration threshold predictive of a complicated postoperative course after elective cardiac surgery in the absence of technical complications and to find..
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Abstract Background: Allogenic blood product transfusion has well-documented risks and adverse outcomes. To limit perioperative transfusions for neonates and infants undergoing cardiac surgery, our institution launched a blood conservation program..
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Abstract Introduction Vasoplegic syndrome (VS) is a severe complication after cardiac surgery with cardiopulmonary bypass (CPB), characterised by vasodilation, hypotension and vasopressor dependence. Endothelial dysfunction, dysregulated nitric oxide signalling, inflammation..
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Abstract Objective We aimed to compare postoperative clinical outcomes between minimally invasive extracorporeal circulation (MiECC) and conventional extracorporeal circulation (CECC) in patients undergoing cardiac surgery. Methods We performed a meta-analysis..
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Abstract Profound, transient hypotension refractory to α1-agonists and increased bypass flow during cardioplegia administration (intermittent vasoplegia) is a well-recognized yet unexplained phenomenon in cardiac surgery. Retrograde cardioplegia has been shown..
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Abstract Objectives To evaluate the association between selective antegrade cerebral perfusion (SACP) flow ranges and early clinical outcomes in a large cohort of patients undergoing aortic arch surgery. Methods We..
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Abstract Up to 40% of cardiac surgery patients present with preoperative anemia, which is associated with significant risks and management challenges. This review highlights the increased perioperative risk attributable to..
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Abstract Introduction Cardiopulmonary bypass (CPB) provokes a systemic inflammatory response with important consequences for infants and children undergoing repair of congenital heart disease [, , ]. Inflammation engages overlapping coagulation..
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Abstract Myocardial protection during cardiopulmonary bypass relies on intermittent administrations of cardioplegia without continuous, tissue‑level feedback on myocardial oxygen supply and mitochondrial metabolic status. Extended near‑infrared spectroscopy (eNIRS) can enable..
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Abstract The gut microbiome has emerged as an important regulator of cardiovascular physiology through interconnected metabolic, immune, inflammatory, and endocrine pathways. Although the gut–heart axis has been extensively investigated in..
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Abstract Background We conducted a technical feasibility and safety study of intraureteric renal negative pressure treatment (rNPT) in patients with chronic kidney disease undergoing elective cardiac surgery with cardiopulmonary bypass..
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Abstract Background and Objectives Acute normovolemic hemodilution (ANH) is an established patient blood management strategy in cardiac surgery, but its effects on postoperative inflammatory biomarkers remain unclear. In this study,..
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Abstract Background Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is used to support refractory cardiogenic shock (CS) but may increase peripheral afterload. Invasive hemodynamic measurement and cardiopulmonary congestion during VA ECMO..
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Abstract Background Patients who undergo tandem extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have a high risk of metabolic disturbances, malnutrition, and fluid imbalances. ECMO/CRRT tandem therapy..
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Abstract Purpose Tolvaptan sodium phosphate (TSP; Samtas®, Otsuka Pharmaceutical, Tokyo, Japan) is a novel intravenous aquaretic diuretic; however, evidence for its use in patients after cardiac surgery is limited. We..
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Abstract Extracorporeal membrane oxygenation (ECMO) is standard for cardiogenic shock, but outcomes remain limited. The BreathMo adult ECMO system with a maglev pump and a low-pressure drop oxygenator was developed...
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Abstract Objectives Diabetes and peri-operative hyperglycaemia are associated with increased morbidity and mortality following cardiac surgery. Despite this, specific guidance on peri-operative glycaemic management during cardiac surgery is lacking in United..
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Abstract Oxidative stress injury is a critical complication during long-term extracorporeal membrane oxygenation (ECMO) support and is further aggravated in critically ill patients with diabetic metabolic comorbidities. Nevertheless, conventional ECMO..
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What the review examined The investigators searched PubMed, the Cochrane Library, Web of Science, Embase, and ClinicalTrials.gov, with a final search on February 9, 2026. The review followed JBI and..
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Abstract Objectives To investigate whether cardiopulmonary bypass (CPB)-induced platelet dysfunction is associated with dysregulated autophagic flux in patients undergoing cardiac surgery. Design Prospective, single-center observational study. Setting A tertiary university..
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Abstract Background Autotransfusion devices concentrate white blood cells (WBCs) within the washed product that may lead to undesirable clinical effects when reinfused to the patient. This quality improvement project evaluated..
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Abstract Background The effects of hollow fiber membrane (HFM) configuration on hemodynamic characteristics, oxygen transfer performance, and thrombosis risk in oxygenators are not clear, and the present study was accomplished..
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Abstract Background This review aims to provide a concise summary of hemodynamic considerations and the pharmacology and current evidence of vasoactive support, including inotropes and vasopressors, during extracorporeal membrane oxygenation..
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Abstract Background: Del Nido cardioplegia (DNC) has extensively been used for pediatric population undergoing cardiac surgery. However, its use in adult cardiac surgeries have been limited thus, its benefits are..
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International Society for Organ Preservation and Perfusion Therapy (ISOPPT) 1st isoppt congress Date: February 19th-20th, 2027 Venue: Turin, Italy CONGRESS PRESIDENT: Renato Romagnoli
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