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Blood Conservation in Cardiac Surgery: In Need of a Transfusion Revolution

Abstract Blood transfusion is the most common procedure in cardiac surgery. Increasing evidence exists that excess transfusions are harmful to patients. Transfusion reactions and complications, including infection, immune modulation, and..

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Risks of Anemia in Cardiac Surgery Patients

Abstract Anemia is an common condition in patients undergoing cardiac surgery, and it is often present in one quarter to half of patients at admission. Several studies have indicated that..

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Acute Kidney Injury in Cardiac Surgery and Cardiac Intensive Care

Abstract Acute kidney injury (AKI) is a serious postoperative complication following cardiac surgery. Despite the incidence of AKI requiring temporary renal replacement therapy being low, it is nonetheless associated with..

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Heparin Resistance Is Common in Patients Undergoing Extracorporeal Membrane Oxygenation but Is Not Associated with Worse Clinical Outcomes

Abstract Extracorporeal membrane oxygenation (ECMO) protocols generally require systemic anticoagulation with heparin to prevent circuit thrombosis. The prevalence, risk factors, and outcomes of heparin resistance in this setting are ill-defined. To better..

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Chest CT features associated with the clinical characteristics of patients with COVID-19 pneumonia

Abstract Objectives Coronavirus disease 2019 (COVID-19) has rapidly swept across the world. This study aimed to explore the relationship between the chest CT findings and clinical characteristics of COVID-19 patients...

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Is emergency and salvage coronary artery bypass grafting justified? The Nordic Emergency/Salvage coronary artery bypass grafting study

Abstract OBJECTIVES According to the EuroSCORE-II criteria, patients undergoing emergency coronary artery bypass grafting (CABG) are operated on before the beginning of the next working day after decision to operate..

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Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity

Abstract Background  is one of the main natural  inhibitors. It is potentiated by heparin, and may be a key component of heparin response, particularly in infants aged <1 year. We sought to..

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Mortality in patients with acute aortic dissection type A: analysis of pre- and intraoperative risk factors from the German Registry…

Abstract OBJECTIVES Acute aortic dissection type A (AADA) is an emergency with excessive mortality if surgery is delayed. Knowledge about independent predictors of mortality on surgically treated AADA patients is..

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Cerebral oximetry the standard monitor of the future?

Abstract Purpose of review  There is an increasing interest in the application of near-infrared spectroscopy (NIRS) as a monitoring tool in noncardiac surgery. This review summarizes the latest developments and..

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Global Incidence and Outcomes of Adult Patients With Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract Objectives To estimate the global incidence and outcomes of  (AKI) after cardiac surgery in adult patients. Design A systematic review and meta-analysis. Setting Cardiac surgery wards. Participants Adult patients after..

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The impact of surgical strategy on survival after repair of type A aortic dissection

Abstract Objective A diverse group of operative strategies are utilized for treatment of acute Stanford type A . We hypothesized that a surgical strategy to prevent cross-clamp injury or false lumen..

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Effects of acute plasma volume expansion on renal perfusion, filtration, and oxygenation after cardiac surgery: a randomized study on crystalloid…

Abstract Background In the present randomized study, we evaluated the differential effects of a colloid and a crystalloid fluid on renal oxygen delivery (⁠RDO2RDO2⁠), glomerular filtration (GFR), renal oxygen consumption..

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Methylene Blue for Vasoplegia When on Cardiopulmonary Bypass During Double-Lung Transplantation

Abstract Vasoplegia syndrome, characterized by hypotension refractory to fluid resuscitation or high-dose vasopressors, low systemic vascular resistance, and normal-to-increased cardiac index, is associated with increased morbidity and mortality after cardiothoracic..

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Are We Overdiagnosing Acute Kidney Injury in Pediatric Patients Following Cardiac Surgery?

Abstract Background: The use of two diagnostic criteria in the current literature has led to some degree of ambiguity in the precise diagnosis of acute kidney injury in pediatric patients..

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Outcome after aortic valve replacement in children: A systematic review and meta-analysis

Abstract Objective Despite an increasing interest in pediatric  repair,  in children may be unavoidable. The evidence on outcome after pediatric aortic valve replacement is limited and usually reported in small case series...

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Hyperbilirubinemia after cardiac surgery: An observational study

Abstract Background We aimed to assess the incidence and perioperative risk factors for hyperbilirubinemia after cardiac surgery, and determine its influence on early operative outcome. Methods This prospective observational study..

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2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients

Abstract Post-cardiotomy extracorporeal life support (PC-ECLS) in adult patients has been used only rarely but recent data have shown a remarkable increase in its use, almost certainly due to improved..

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Central extracorporeal membrane oxygenation for refractory pediatric septic shock

Abstract Objective: To demonstrate positive outcome, to achieve higher flow rates, and to reverse shock more quickly by implementing central extracorporeal membrane oxygenation (ECMO) in children with refractory septic shock. Children..

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Extracorporeal Membrane Oxygenation for Adults With Refractory Septic Shock

Abstract Because of a severe dysregulation of the host response to infection, septic shock may induce a profound imbalance between oxygen consumption and delivery, which in some cases may be..

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Neonatal Closure of Apical Ventricular Septal Defect

Abstract A 2-week-old, 3.5 kg child was transferred from a distant hospital (300 miles away) on congestive heart failure. Suspected diagnosis was ventricular septal defect (VSD), atrial septal defect (ASD),..

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Publication in The New England Journal of Medicine shows complications after liver transplantation significantly reduced with cold, oxygenated machine perfusion.

Abstract An article published in the scientific journal The New England Journal of Medicine, shows that oxygenated perfusion of the donated liver before transplantation has a significant positive impact on..

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Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs

Abstract Background Extracorporeal life support (ECLS) has become an integral part of modern intensive therapy. The choice of support mode depends largely on the indication. Patients with respiratory failure are..

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The Hemovent Oxygenator: A New Low-Resistance, High-Performance Oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) provide respiratory support aimed at gaining time to allow patient’s recovery from hypoxemic and/or hypercapnic respiratory failure, respectively. However, in..

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Minimum Alveolar Concentration of Sevoflurane as a Single Hypnotic Agent to Maintain BIS Below 50 in Patients During Normothermic Cardiopulmonary…

Abstract Objectives Minimum alveolar concentration (MAC) of volatile anesthetic agents to maintain bispectral index (BIS) below 50 in 50% of patients was defined as MACBIS50. The primary objective of this..

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Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance

Abstract Case Report A 72-year-old man with a tachycardiomyopathy, atrium flutter, and atrial fibrillation underwent an elective radiofrequency ablation procedure. In addition to 5 mg of apixaban twice daily, his..

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Thromboelastometry, Thromboelastography, and Conventional Tests to Assess Anticoagulation During Extracorporeal Support: A Prospective Observational Study

Abstract Optimal anticoagulation monitoring in patients with extracorporeal membrane oxygenation (ECMO) is fundamental to avoid hemorrhagic and thromboembolic complications. Besides conventional coagulation tests, there is growing interest in the use..

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Extracorporeal membrane oxygenation versus mechanical ventilation alone in adults with severe acute respiratory distress syndrome: A systematic review and meta‐analysis

Abstract Background COVID‐19 can lead to acute respiratory distress syndrome (ARDS). Extracorporeal membrane oxygenation (ECMO) is considered to be a salvage strategy for severe ARDS. However, the effect of ECMO..

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The Role of Hyperthermic Intraperitoneal Chemotherapy in Pseudomyxoma Peritonei After Cytoreductive Surgery

Abstract Importance  Studies on the prognostic role of hyperthermic intraperitoneal chemotherapy (HIPEC) in pseudomyxoma peritonei (PMP) are currently not available. Objectives  To evaluate outcomes after cytoreductive surgery (CRS) and HIPEC compared with..

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Observational study of thrombosis and bleeding in COVID-19 VV ECMO patients

Abstract Introduction: COVID-19 has been associated with increased risk of thrombosis, heparin resistance and coagulopathy in critically ill patients admitted to intensive care. We report the incidence of thrombotic and..

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Hypofibrinogenemia can be estimated by the predictive formula in aortic surgery

Abstract Objective Aortic surgery often causes massive bleeding due to hypofibrinogenemia. Predicting hypofibrinogenemia is useful for developing a hemostasis strategy, including preparing for blood transfusion. We made a formula for..

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