Abstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..
Read MoreAbstract Background Goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) commonly targets indexed oxygen delivery (DO2i), yet fixed delivery thresholds may ignore patient-specific metabolic demand. The oxygen extraction ratio (O2ER) integrates..
Read MoreAbstract Heart transplantation (HT) is the definitive therapy for end-stage heart failure. Patients unwilling to receive blood product transfusions are often considered ineligible for HT due to the significant perioperative..
Read MoreAbstract Background Simulation-based education is a well-established training technique in medical curricula, also for communication skills. Virtual reality (VR) technology can enhance this form of experience-based learning. How VR interacts..
Read MoreAbstract Dear Editor, The timely liberation of cardiogenic shock (CS) patients from veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is crucial to reduce device complications, although the predictor of weaning is..
Read MoreAbstract OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) is a critical intervention for patients with severe cardiac or respiratory failure. However, pharmacological management for ECMO-supported patients presents unique challenges due to alterations..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is a critical life-support therapy for patients with severe cardiac and/or respiratory failure, but it carries a significant risk of neurological complications. This narrative review..
Read MoreAbstract Objectives: This study aimed to assess whether continuous furosemide administration during cardiopulmonary bypass (CPB) in minimally invasive cardiac surgery (MICS) reduces the incidence of cardiac surgery-associated acute kidney injury..
Read MoreAbstract The use of left-sided Impella microaxial flow pumps has expanded rapidly for the management of cardiogenic shock, left ventricular unloading and as a bridge to heart transplantation. However, standard..
Read MoreLVAD Implantation in Pediatric Population inflow from LV and outflow to Ascending Aorta. LVAD Implantation in the Pediatric Population By Sam Zeraatiannejaddavani, MD ⸻ A —..
Read MoreHow to Prime an EVLP device from A to Z with back table LA and PA cuff srcuring and Dextran Priming as well connecting to EVLP. Dr.Sam Zeraatian Nejad..
Read MoreAbstract Background Increased postoperative glycemic variability (GV) has been shown to be associated with an increased risk for adverse outcomes. However, the impact of postoperative GV on the long-term mortality..
Read MoreAbstract Background Although delivering less oxygen is associated with acute kidney injury, little is known about its association with long-term mortality and how the association may be modified by transfusion...
Read MoreAbstract Introduction Mobility and rehabilitation for patients supported on extracorporeal life support (ECLS) are high-risk and resource-intensive endeavors that currently lack a standardized framework to guide comprehensive program development. This..
Read MoreAbstract Invasive mechanical ventilation remains a cornerstone in the treatment of critically ill patients suffering from acute respiratory failure, providing life-sustaining gas exchange while necessitating careful selection of modes and..
Read MoreAbstract Objectives To evaluate the effectiveness of Artificial Intelligence (AI) in improving clinical outcomes in Extracorporeal Membrane Oxygenation (ECMO) management, focusing on ECMO initiation, prognosis, and complications. Methods A meta-analysis following..
Read MoreAbstract Background Patients supported with veno-arterial extracorporeal membrane oxygenation may receive an intra-aortic balloon pump to reduce left ventricular afterload and improve aortic diastolic pressure. However, the effect of this..
Read MoreCardiopulmonary bypass is established following systemic heparinization to achieve an activated clotting time greater than four hundred and eighty seconds. Arterial cannulation is performed in the ascending aorta, while..
Read MoreHeart Recovery Techniques A. Donor Types 1. DBD (Donation after Brain Death) •Traditional and most common •Heart remains perfused until cross-clamp •Predictable ischemic time 2. DCD (Donation after Circulatory Death)..
Read MoreAbstract Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success..
Read MoreAbstract Cardiac surgery triggers a systemic inflammatory response, especially when cardiopulmonary bypass (CPB) is used, which may contribute to postoperative complications. Ketamine, an NMDA receptor antagonist, has shown anti-inflammatory potential..
Read MoreAbstract We evaluated the accuracy and precision of zero-heat flux (ZHF) and dual sensor (DS) non-invasive temperature probes in intensive care unit (ICU) patients undergoing hypothermic temperature control, hypothesizing that..
Read MoreAbstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is used to treat refractory lung failure, a condition that often results in right ventricular dysfunction, which can exacerbate both morbidity and mortality...
Read MoreAbstract Calcium channel blocker (CCB) toxicity can lead to cardiogenic shock and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) has been used as salvage therapy when conventional treatments fail, but outcomes..
Read MoreAbstract Cardiac surgery, while life-saving, induces profound physiological stress due to ischemia–reperfusion injury (IRI), systemic inflammation, and endothelial dysfunction, particularly in procedures involving cardiopulmonary bypass. In this complex setting, extracellular..
Read MoreAbstract Type 2 Diabetes Mellitus (T2DM) is a chronic disease caused by the resistance of tissues to the actions of insulin as well as the progressive failure to produce adequate..
Read MoreAbstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..
Read MoreAbstract Cardiopulmonary bypass (CPB) can lead to cardiac damage due to oxidative stress (OS) and inflammation in heart failure (HF). We tested the hypothesis that preoperative HF patients with reduced..
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