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The cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest: A Systematic Review

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory cardiac arrest across the world, but its cost-effectiveness remains uncertain. We conducted this systematic review to assess the available..

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Expanding ECMO Horizons: Shock and Temporary Mechanical Circulatory Support - Nov 14

University Conference Center Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine 30 Conference Dr. Hershey, PA 17033 Internet Live Course This training will be..

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Intraoperative cell salvage. Benefit to patients when anticipated blood loss >1000ml.

In modern surgical practice,managing perioperative blood loss typically exceeding 500ml to 1liter. is a critical factor impacting patient outcomes ,morbidity and resource mobilization. TYPES OF TRANSFUSION Allogeneic(Homologous) blood transfusion involves..

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Cardiac Surgery During and After the Pandemic: A Retrospective Analysis of UK Trends and Outcomes

Abstract Objectives The full extent of the COVID-19 pandemic’s impact during different phases of the pandemic and the recovery of cardiac surgical services in the United Kingdom have not been..

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Residual Heparinization After Cardiac Surgery:A Prospective Observational Study

Abstract Objectives Residual heparinization is a preventable cause of coagulopathy following cardiac surgery. The aim of this work was to assess the proportion of patients with residual heparinization following cardiac..

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Endothelial Activation and Permeability in Patients on VV-ECMO Support: An Exploratory Study

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports critically ill patients with respiratory failure. However, ECMO may induce systemic inflammation, hemolysis, and hemodilution, potentially resulting in endothelial activation and damage. Therefore,..

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An initiative to reduce blood stream infections (BSI) in patients on ECMO

Abstract Introduction Blood Stream Infections (BSI) occur in 3-35% of patients on ECMO (Extracorporeal membrane Oxygenation). With the increased use of ECMO since the COVID-19 pandemic, the magnitude of this..

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Blood transfusion and acute kidney injury after cardiac surgery: a retrospective observational study

Abstract Purpose Cardiac surgery-associated acute kidney injury (AKI) is linked to poor outcomes. An observational study from Copenhagen, Denmark identified perioperative red blood cell (RBC) transfusion as a modifiable risk..

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Gaseous Microemboli and Postoperative Delirium in Coronary Artery Bypass Grafting

Abstract Background: Postoperative delirium (POD) is a neurocognitive syndrome affecting patients undergoing surgery. It is a frequent complication of coronary artery bypass grafting (CABG) and is associated with higher morbidity,..

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Single venous cannulation for bi-atrial venoarterial extracorporeal membrane oxygenation in bridge to transplantation: a two-in-one approach

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) often leads to left ventricular (LV) overload, particularly in patients with biventricular cardiogenic shock. This increased afterload can hinder cardiac muscle recovery and cause..

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Methylprednisolone and Endothelial Dysfunction in Cardiac Surgery: A Pilot Randomized Trial

Abstract Background Cardiac surgery involving cardiopulmonary bypass (CPB) serves as a clinical model of ischemia–reperfusion injury and endothelial dysfunction. Endothelial injury is often manifested clinically by vasoplegia and microcirculatory disturbances...

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Activated Clotting Time and Haemostatic Complications in Patients Receiving ECMO Support: A Systematic Review

Abstract Background: Extracorporeal membrane oxygenation (ECMO) requires systemic anticoagulation to prevent clotting, typically using unfractionated heparin (UFH). However, anticoagulation carries a bleeding risk, necessitating monitoring. Activated clotting time (ACT) is..

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Risk–stratified outcomes of red blood cell transfusion in on–pump cardiac surgery

Abstract To the Editor: Red blood cell (RBC) transfusion is commonly performed during on-pump cardiac surgery; however, excessive use may lead to adverse clinical outcomes and medical resources wastage.[] The call..

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Global Survey of Extracorporeal Membrane Oxygenation Transport Programs: Variability in Team Composition, Training, and Capabilities

Abstract Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary support associated with improved survival in severe respiratory failure and refractory cardiac arrest. Extracorporeal membrane oxygenation is highly specialized and..

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Prognostic scores of extracorporeal membrane oxygenation: a scoping review

Abstract BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is an effective measure for saving the lives of critically ill patients. Prompt identification of the risk factors for mortality among patients receiving ECMO and..

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Comparison of Two Activated Clotting Time Targets During Cardiac Surgery With Cardiopulmonary Bypass: A Prospective Multicenter Randomized Controlled Trial

Abstract Objectives The present study was designed to investigate the equivalence of two target activated clotting time (ACT) values with regard to packed red blood cell (PRBC) transfusion in patients..

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Extracorporeal Cardiopulmonary Resuscitation: Reviewing the Evidence and Exploring Its Equitable Implementation in the UK National Health Service

Abstract Cardiac arrest outcomes remain historically poor with survival to hospital discharge less than 2.2% in the UK (). Refractory cardiac arrest is characterized by a persistent loss of circulation..

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High vasoactive-inotropic score is associated with poor outcomes in patients undergoing coronary artery bypass grafting: A systematic review and meta-analysis

Abstract Background Vasoactive-inotropic score (VIS) has been previously utilized as one of the predictors in open heart procedures postoperatively, but its association with poor outcomes in patients who underwent coronary..

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Selective visceral perfusion in thoracoabdominal aortic surgery: optimal flow rate in a porcine model

Abstract To determine the optimal perfusion volume for the celiac artery (CA) and superior mesenteric artery (SMA) in a porcine model. Fifteen Yorkshire pigs (46.7 ± 5.2 kg) underwent selective CA and..

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Tolerating cardiovascular health disparities is a failure of science and society

Abstract Cardiovascular disease is responsible for  of all deaths in Europe. Decades of research and investment have achieved impressive declines in overall cardiovascular disease mortality, yet this progress hides a persistent..

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Does normothermic regional perfusion harm donors after circulatory death?

Abstract Normothermic regional perfusion during controlled donation after circulatory death has emerged as a means to increase the number and viability of organs available for transplant. Because normothermic regional perfusion..

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Re-evaluating the association between thrombocytopenia and bleeding in extracorporeal membrane oxygenation (ECMO)

Abstract Objectives The platelet trigger at which to transfuse platelets to prevent bleeding complications in patients supported with extracorporeal membrane oxygenation (ECMO) is unclear. We aimed to elucidate the association..

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Association between intraoperative lactate levels and acute kidney injury after on-pump cardiac surgery: a retrospective cohort study across two centers

Abstract Background Hyperlactatemia and acute kidney injury (AKI) represent significant perioperative complications in cardiac surgery. This study investigated their relationship by analyzing multiple lactate parameters during on-pump cardiac procedures. Methods..

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Impact of Preoperative Extracorporeal Membrane Oxygenation Use on Lung Transplant Outcomes

Abstract Background  (ECMO) may be used to support critically ill patients before . The relationship between preoperative venoarterial and venovenous ECMO and their relationship with  indications remain poorly elucidated. Methods This study..

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Temporary Mechanical Circulatory Support in Cardiogenic Shock: Executive Summary of the Joint Consensus Reports of the PeriOperative Quality Initiative and…

Abstract Background The identification, triage, and management of cardiogenic shock (CS) are complex and resource intensive, particularly given the recent surge in the use of temporary mechanical circulatory support (tMCS)..

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Malperfusion, Malperfusion Syndrome, and Mesenteric Ischemia in Aortic Dissection

Abstract Aortic malperfusion occurs in a significant percentage of patients with acute , and causes , the clinical entity defined by end organ , in 10–33% of patients. Malperfusion syndrome can be rapidly..

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The role of the modified Glasgow prognostic score in predicting postoperative mortality following open-heart surgery

Abstract PurposeThe Modified Glasgow Prognostic Score is an inflammation-based index utilizing C-reactive protein and albumin levels. It has been investigated in various diseases such as cancer, heart failure, and myocardial..

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Pulmonary arterial hypertension in neonates and children post open-heart surgery: assessment and management including extracorporeal membrane oxygenation (ECMO) — a…

Abstract Background Congenital heart disease (CHD) that requires heart surgery is common. Severe postoperative pulmonary hypertension (PH) occurs in 2% of cardiac procedures and is associated with high morbidity and..

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Experimental Comparison of Esmolol- and Blood-Based Cardioplegia for Long Aortic Clamping Times

Abstract Objectives After cardiac surgery, long aortic clamping times and extracorporeal circulation times are associated with worse outcomes. This study compares hemodynamic performance, myocardial metabolism, and ultrastructural preservation in rat..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion? Think High!

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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