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Causes of red blood cell loss during extracorporeal membrane oxygenation

Abstract Background Pediatric patients on extracorporeal membrane oxygenation (ECMO) often receive repeated red blood cell (RBC) transfusions. This study aims to quantify and characterize causes of RBC loss on ECMO...

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Ventricular Flow Dynamics with an Intra-Ventricular Balloon Pump: An In Vitro Analysis

Abstract Due to the high treatment costs associated with durable ventricular assist devices, an intra-ventricular balloon pump (IVBP) was developed to provide low-cost, short-term support for patients suffering from severe..

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Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation

Abstract Background Anti-human leukocyte antigen (HLA)-antibody production represents a major barrier to heart transplantation, limiting recipient compatibility with potential donors and increasing the risk of complications with poor waiting-list outcomes...

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Prolonged Periods of Antegrade Cerebral Perfusion Are Safe During Elective Arch Surgery

Abstract Background Cerebral circulatory arrest times >40 minutes during  have previously been shown to be associated with increased morbidity and mortality. The purpose of this study was to redefine what would..

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Cardiopulmonary Bypass Emergencies and Intraoperative Issues

Abstract Cardiopulmonary bypass (CPB) is a complex biomechanical engineering undertaking and an essential component of cardiac surgery. However, similar to all complex bioengineering systems, CPB activities are prone to a..

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Neonatal ECMO survivors: The late emergence of hidden morbidities – An unmet need for long-term follow-up

Abstract Since the initiation of Extracorporeal Life Support Organization (ELSO) Registry in 1989, more than 47,000 neonates treated with extracorporeal membrane oxygenation (ECMO) have been registered worldwide with an overall..

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Certified Registered Nurse Anesthetists’ occupational exposure to inhalational anesthetic agents: a survey of anesthetic gas safety

Abstract Background Anesthetic gases have been known to cause damage when inhaled over long periods of time. Modern safety measures have been put in place to reduce the risk to..

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Early predictors of oxygenator exchange during veno-venous extracorporeal membrane oxygenation: A retrospective analysis

Abstract Introduction: Oxygenator exchange during extracorporeal membrane oxygenation (ECMO) is a life-threatening procedure. D-dimer has been used to predict oxygenator failure, but it is a parameter used a few days..

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Perioperative Management of the Patient at High-Risk for Cardiac Surgery-Associated Acute Kidney Injury

Abstract Acute kidney injury (AKI) is one of the most common major complications of cardiac surgery, and is associated with increased morbidity and mortality. Cardiac surgery-associated AKI has a complex,..

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Heart tumor between RPA and LA

Patient with Heart tumor between RPA and LA undergone extensive resection of tumor with beating heart. [playlist ids="38181"]   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center..

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Off Pump Aortic Valve vegectomy as well as TV BE vegectomy

off Pump Aortic Valve vegectomy as well as TV BE vegectomy.   [playlist ids="38176"] Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of..

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Malignant Course of RCA between Ascending aorta and pulmonary trunc

Malignant Course of RCA between Ascending aorta and pulmonary trunc confirmed by clinical symptoms and conventional Angio and CTA undergone detachment and réimplantation of RCA trunc. [playlist ids="38150"]   Dr.Sam..

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Severe Mitral stenosis and diaphragmatic hernia

90 years old female with RT sided diaphragmatic hernia and Severe Mitral stenosis undergone simultaneous repair with good course and post op xray. [gallery ids="38141"] [playlist ids="38145"]   Dr.Sam Zeraatian..

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Assessment of Rotational Thromboelastometry and Thrombin Generation Assay to Identify Risk of High Blood Loss and Re-Operation After Cardiac Surgery

Abstract Introduction: We aimed to investigate parameters for prediction of post-operative blood loss and re-operation in patients who underwent cardiopulmonary bypass.  Methods: Thrombin generation assay, activated partial thromboplastin time, activated clotting time..

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Oxygenator impact on meropenem/vaborbactam in extracorporeal membrane oxygenation circuits

Abstract Introduction: To determine the oxygenator impact on alterations of meropenem (MEM)/vaborbactam (VBR) in a contemporary neonatal/pediatric (1/4-inch) and adolescent/adult (3/8-inch) extra corporeal membrane oxygenation (ECMO) circuit including the Quadrox-i® oxygenator...

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In-situ modified polyethersulfone oxygenation membrane with improved hemocompatibility and gas transfer efficiency

Abstract Extracorporeal membrane oxygenation (ECMO) is one of the most important supporting therapies for patients with severe cardiopulmonary failure, and the core component of ECMO is the membrane oxygenator. However,..

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Medical nutrition therapy in patients receiving ECMO: Evidence-based guidance for clinical practice

Abstract Patients receiving extracorporeal membrane oxygenation (ECMO) inherit substantial disease-associated metabolic, endocrinologic, and immunologic modifications. Along with the technical components of ECMO, the aforementioned alterations may affect patients' needs and..

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Normothermic Versus Hypothermic Norwood Procedure

Abstract Background Either deep hypothermia with circulatory arrest or hypothermic perfusion with antegrade selective cerebral perfusion is used during the Norwood procedure for hypoplastic left heart syndrome. Normothermic perfusion has..

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Role of nebulized heparin in mechanically ventilated critically ill patients

Abstract Background  Mechanical ventilation is a technique for supporting or substituting respiration. Fibrin deposition in the pulmonary microcirculation and alveolar sacs (hyaline membrane generation) is a major inflammatory route of..

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The multifactorial dynamic perfusion index: A predictive tool of cardiac surgery associated acute kidney injury

Abstract Introduction Cardiac surgery associated acute kidney injury (CSA-AKI) has a number of preoperative and intraoperative risk factors. Cardiopulmonary bypass (CPB) factors have not yet been elucidated in a single..

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Cardiopulmonary bypass parameters improve the prediction of 30-day mortality following cardiac surgery

Abstract Currently 30-day mortality is commonly used as a quality indicator for cardiac surgery; however, prediction models have not included the role of cardiopulmonary bypass (CPB). We hypothesized that reproducing..

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Factor XII Silencing Using siRNA Prevents Thrombus Formation in a Rat Model of Extracorporeal Life Support

Abstract Heparin anticoagulation increases the bleeding risk during extracorporeal life support (ECLS). This study determined whether factor XII (FXII) silencing using short interfering RNA (siRNA) can provide ECLS circuit anticoagulation without bleeding. Adult..

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MV cleaning with LA size reduction, 3th redo

Three Do sternotomy and MV cleaning with LA size reduction.   [gallery ids="38103"] [playlist ids="38107"] Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head..

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SVCS and bacterial endocarditis

SVCS and bacterial endocarditis undergone SVC reconstruction with bovine pericardial patch.   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of IUMS transplant..

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Complete SVC occlusion with SVC syndrome

Patient with ESRD and dialysis Catheter and complete SVC occlusion with SVC syndrome undergone complete SVC reconstruction with Bovine pericardial patch.   [gallery ids="38097"] Dr.Sam Zeraatian Nejad Davani, CEO of..

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Antegrade cardioplegia

Cardioplegia is a pharmacological therapy administered during cardiac surgery to intentionally and temporarily arrest the heart. The first solution used during cardiopulmonary bypass was reported by Dr. Melrose in the..

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Venous cannulation

Technical Aspects of Cardiopulmonary Bypass Process Overview Blood is drained from the vena caval filters directly into a reservoir. Normally a single two-stage cannula is used (drains blood from the..

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Diagnostic and Therapeutic Implications of Ex Vivo Lung Perfusion in Lung Transplantation: Potential Benefits and Inherent Limitations

Abstract Ex vivo lung perfusion (EVLP), a technique in which isolated lungs are continually ventilated and perfused at normothermic temperature, is emerging as a promising platform to optimize donor lung..

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