Abstract Background Increased postoperative glycemic variability (GV) has been shown to be associated with an increased risk for adverse outcomes. However, the impact of postoperative GV on the long-term mortality..
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Abstract Background Although delivering less oxygen is associated with acute kidney injury, little is known about its association with long-term mortality and how the association may be modified by transfusion...
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Abstract Introduction Mobility and rehabilitation for patients supported on extracorporeal life support (ECLS) are high-risk and resource-intensive endeavors that currently lack a standardized framework to guide comprehensive program development. This..
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Abstract Invasive mechanical ventilation remains a cornerstone in the treatment of critically ill patients suffering from acute respiratory failure, providing life-sustaining gas exchange while necessitating careful selection of modes and..
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Abstract Objectives To evaluate the effectiveness of Artificial Intelligence (AI) in improving clinical outcomes in Extracorporeal Membrane Oxygenation (ECMO) management, focusing on ECMO initiation, prognosis, and complications. Methods A meta-analysis following..
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Abstract Background Patients supported with veno-arterial extracorporeal membrane oxygenation may receive an intra-aortic balloon pump to reduce left ventricular afterload and improve aortic diastolic pressure. However, the effect of this..
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Abstract Background and clinical significance. Penetrating cardiothoracic wounds require prompt treatment in order to decrease mortality and morbidity. Surgical therapy, aimed at bleeding control and removal of damaged tissue, varies widely..
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Cardiopulmonary bypass is established following systemic heparinization to achieve an activated clotting time greater than four hundred and eighty seconds. Arterial cannulation is performed in the ascending aorta, while..
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Heart Recovery Techniques A. Donor Types 1. DBD (Donation after Brain Death) •Traditional and most common •Heart remains perfused until cross-clamp •Predictable ischemic time 2. DCD (Donation after Circulatory Death)..
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Abstract Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success..
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Abstract Cardiac surgery triggers a systemic inflammatory response, especially when cardiopulmonary bypass (CPB) is used, which may contribute to postoperative complications. Ketamine, an NMDA receptor antagonist, has shown anti-inflammatory potential..
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Abstract We evaluated the accuracy and precision of zero-heat flux (ZHF) and dual sensor (DS) non-invasive temperature probes in intensive care unit (ICU) patients undergoing hypothermic temperature control, hypothesizing that..
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Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is used to treat refractory lung failure, a condition that often results in right ventricular dysfunction, which can exacerbate both morbidity and mortality...
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Abstract Calcium channel blocker (CCB) toxicity can lead to cardiogenic shock and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) has been used as salvage therapy when conventional treatments fail, but outcomes..
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Abstract Cardiac surgery, while life-saving, induces profound physiological stress due to ischemia–reperfusion injury (IRI), systemic inflammation, and endothelial dysfunction, particularly in procedures involving cardiopulmonary bypass. In this complex setting, extracellular..
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Abstract Type 2 Diabetes Mellitus (T2DM) is a chronic disease caused by the resistance of tissues to the actions of insulin as well as the progressive failure to produce adequate..
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Abstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..
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Abstract Cardiopulmonary bypass (CPB) can lead to cardiac damage due to oxidative stress (OS) and inflammation in heart failure (HF). We tested the hypothesis that preoperative HF patients with reduced..
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Abstract Introduction Haemoglobin measurement is an essential parameter for quantifying anaemia and often used for guiding transfusion decisions. Conventional methods require blood sampling and are invasive. Results are intermittent, discontinuous..
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Abstract In the high-stakes realm of extracorporeal membrane oxygenation (ECMO), every decision can have profound consequences—from initiation to termination. Management controversies persist throughout the entire course. Beyond patient selection, timing,..
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Abstract Background: Discontinuing mechanical ventilation during cardiopulmonary bypass (CPB) is common but may adversely affect postoperative pulmonary function. This study aimed to evaluate the impact of stopping ventilation during CPB..
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Abstract Background Organ dysfunction after cardiac surgery may be reduced by dexmedetomidine. We evaluated whether perioperative dexmedetomidine reduces complications after cardiac surgery with cardiopulmonary bypass. Methods In this randomised, double-blind,..
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Abstract Although protamine induces cardiotoxicity, ulinastatin has been shown to attenuate protamine-induced cardiotoxicity in rats. However, whether ulinastatin alleviates protamine-induced cardiac depression during cardiac surgery remains unclear. This study aimed..
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Abstract The pervasive presence of microplastics and nanoplastics (MNPs) in the environment has raised growing concerns regarding their potential health impacts. While research has progressively revealed the toxicological effects of..
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Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving therapy for patients with severe cardiac failure. If patients can be weaned, withdrawal and closure of the large-bore arterial access..
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Abstract Background Children with heart disease and cardiopulmonary failure may be supported with extracorporeal membrane oxygenation (ECMO) for stabilization before cardiac surgery. This study describes their epidemiology and outcomes. Methods..
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Abstract BACKGROUND: This single center study analyzed epidemiology, outcomes, and three-year quality of life (QoL) of critically ill COVID-19 patients requiring a possibly life-saving VV-ECMO. METHODS: Demographics, clinical and technical..
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Abstract Background Acute renal impairment following cardiopulmonary bypass (CPB) is a serious perioperative complication with sustained occurrence. Proactive risk assessment and preventive strategies are crucial for enhancing surgical outcomes. Methods..
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Abstract Purpose Chatbots have enhanced student engagement and learning outcomes in education. Simulation-based training is critical in perfusion education, providing risk-free environments for skill mastery and clinical readiness. This research..
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Abstract The evolution of extracorporeal membrane oxygenation (ECMO) has led to an increasing reliance on objective parameters to detect complications early and enhance patient safety. One such parameter is the..
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