Albumin solution was no better than Ringer acetate at reducing complications from cardiac surgery with cardiopulmonary bypass in a randomized clinical trial.

Likelihood of at least one major adverse event within 90 days after elective surgery — counting death, myocardial injury, acute heart failure, resternotomy stroke, arrhythmia, bleeding, infection, and acute kidney failure — did not differ whether 4% albumin or Ringer acetate had been administered as a cardiopulmonary bypass primer and perioperative intravenous volume replacement (RR 1.10, 95% CI 0.95-1.27), according to the ALBICS study published in JAMA.