Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and European Coronary Artery Bypass Grafting Bleeding Severity Grade
Abstract
Editor’s Perspective
What We Already Know about This Topic
- Major bleeding can occur during cardiac surgery. Although different scoring systems exist, the assessment of bleeding can be variable, and the reliability of these scoring systems has not been determined.
What This Article Tells Us That Is New
- Two consensus-based scoring systems for assessing bleeding were compared in a substudy of the Transfusion Avoidance in Cardiac Surgery trial. Both the Universal score and European Coronary Artery Bypass Graft scores performed well and may be used as validated outcome measures in future clinical trials.
Background
Research into major bleeding during cardiac surgery is challenging due to variability in how it is scored. Two consensus-based clinical scores for major bleeding: the Universal definition of perioperative bleeding and the European Coronary Artery Bypass Graft (E-CABG) bleeding severity grade, were compared in this substudy of the Transfusion Avoidance in Cardiac Surgery (TACS) trial.