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Partial Heart Transplantation in Adult Cardiac Surgery

Abstract Many young adults require heart valve replacements. Current options for valve replacement in adults include mechanical valves, bioprosthetic valves, or the Ross procedure. Of these, mechanical and bioprosthetic valves..

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The Future of heart procurement with donation after circulatory death: Current practice and opportunities for advancement

Abstract Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from . However, the expansion of DCD  is currently limited by unanswered questions pertaining..

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Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo/YAP signaling after lung injury

Abstract Background The preferred configuration for bridging patients with respiratory failure while awaiting  is venovenous  (VV ECMO). However, the protective effect of VV ECMO on the lung, as well as the underlying..

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New horizons for reduction of blood use: Patient blood management

Abstract A countrywide study over the eras indicates overuse of blood transfusion can have considerable risks to patients accompanied by significant costs of blood transfusion for patients, hospitals, and health-care..

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VA-ECMO Cardiac Support During Liver Transplant: A Case Report

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for cardiovascular collapse during and after liver transplantation (LT). According to the most recent guidelines, patients with severe cardiomyopathy are excluded..

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Additional Extracorporeal Membrane Oxygenation Pump Without an Oxygenator for Transseptal Left Atrial Decompression: A Case Report

Abstract A 63-year-old man developed chest pain and dyspnea. Venoarterial-venous extracorporeal membrane oxygenation (ECMO) was applied to the patient due to failing heart after percutaneous coronary intervention. We used an..

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Elective and non-elective endomyocardial biopsy in heart transplant patients and procedural outcomes: An IMPACT registry analysis

Abstract Background Endomyocardial biopsies are standard of care for transplant surveillance, however the procedural risks are not well established, especially in children. The purpose of the study was therefore to..

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Ex-situ oxygenated hypothermic machine perfusion in donation after circulatory death heart transplantation following either direct procurement or in-situ normothermic regional…

Abstract Background Heart transplantation in donation after circulatory death (DCD) relies on warm perfusion using either in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion. In this..

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Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement

Abstract Combined advances in haematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with haematological malignancies admitted to the intensive care unit. In cases of..

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PROTOCOLO NACIONAL DE TRASPLANTE CARDíACO INFANTIL AB0 INCOMPATIBLE

Abstract La práctica del trasplante AB0 incompatible (AB0i) surgió en el Hospital Sick Children de Toronto (Canadá) bajo el liderazgo de la Doctora Lori J. West, cardióloga e inmunóloga pediátrica..

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Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review

Abstract A growing body of evidence supports the use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) refractory to maximal medical therapy. ARDS may develop in..

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Extracorporeal Membrane Oxygenation in Acute Respiratory Failure

Abstract Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is a form of mechanical life support that provides full respiratory bypass in patients with severe respiratory failure as a bridge to recovery..

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Surgical Science and the Evolution of Critical Care Medicine

Abstract Surgical science has driven innovation and inquiry across adult and pediatric disciplines that provide critical care regardless of location. Surgically originated but broadly applicable knowledge has been globally shared..

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Planned Extracorporeal Life Support Employment during Liver Transplantation: The Potential of ECMO and CRRT as Preventive Therapies—Case Reports and Literature…

Abstract Liver Transplantation (LT) has become the gold standard treatment for End-Stage Liver Disease (ESLD). One of the main strategies to manage life-threatening complications, such as cardio-respiratory failure, is Extracorporeal..

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Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation

Abstract Background Anti-human leukocyte antigen (HLA)-antibody production represents a major barrier to heart transplantation, limiting recipient compatibility with potential donors and increasing the risk of complications with poor waiting-list outcomes...

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Diagnostic and Therapeutic Implications of Ex Vivo Lung Perfusion in Lung Transplantation: Potential Benefits and Inherent Limitations

Abstract Ex vivo lung perfusion (EVLP), a technique in which isolated lungs are continually ventilated and perfused at normothermic temperature, is emerging as a promising platform to optimize donor lung..

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Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome

Abstract Background Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis..

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Effect of Autotransfusion in HCC Surgery on Survival and Recurrence: A Systematic Review and Meta-Analysis

Abstract Background: The chronic blood shortage has forced clinicians to seek alternatives to allogeneic blood transfusions during surgery. Due to anatomic uniqueness resulting in a vast vasculature, liver surgery can..

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Patterns of Use in Transesophageal Echocardiography for Liver Transplantation: A Systematic Review

Abstract Transesophageal echocardiography is frequently but not always used to guide anesthetic management during liver transplantation. We performed a systematic review of the literature to identify and summarize any studies..

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Decline in Functional Status While on the Waiting List Predicts Worse Survival After Lung Transplantation

Abstract Objectives To determine if decreases in the Karnofsky Performance Score (KPS) while on the waitlist predict decreased survival after lung transplantation (LTx). Design A retrospective evaluation of the United..

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Clinical approach to acute cellular rejection from the pediatric heart transplant society

Abstract Background Early detection of cardiac allograft rejection is crucial for post-transplant graft survival. Despite the progress made in immunosuppression strategies, acute cellular rejection remains a serious complication during and..

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Fractured Right Atrial-Pulmonary Artery Cannula (ProtekDuo) in a 164-Day Extracorporeal Membrane Oxygenation Bridge to Lung Transplant

Abstract Fractures of extracorporeal membrane oxygenation (ECMO) cannulas are exceedingly rare due to their woven metal reinforcement. There are only a few cases reported in the literature. We present a 27-year-old..

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Hybrid and parallel extracorporeal membrane oxygenation circuits

Abstract Extracorporeal membrane oxygenation (ECMO) is one type of extracorporeal life support for patients with cardiopulmonary failure. ECMO may serve as a as bridge to recovery, long-term mechanical support, or..

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Recurrent Candidemia Due to Extracorporeal Membrane Oxygenation Circuit Seeding in Acute Respiratory Distress Syndrome From COVID-19

Abstract Nosocomial infections are a leading complication of prolonged extracorporeal membrane oxygenation (ECMO) therapy, and invasive fungal infections are of particular concern. Candida bloodstream infection specifically is associated with poor outcomes in acute..

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Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant

Abstract Heart transplant remains the most durable treatment for end-stage congestive heart failure. Since the first successful human heart transplant performed by Barnard in 1967, advances in organ procurement, understanding..

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Perioperative Circulatory Support and Management for Lung Transplantation: A Case-Based Review

Abstract Lung transplantation (LTx) historically was performed with cardiopulmonary bypass (CPB) or Off-pump. Recent data suggest an increased interest in extracorporeal membrane oxygenation (ECMO) as perioperative circulatory support by many..

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Initial hospital length of stay and long-term survival of patients successfully resuscitated using extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac…

Abstract Aims The long-term outcomes of patients treated with extracorporeal cardiopulmonary resuscitation (ECPR) for refractory ventricular tachycardia/ventricular fibrillation (VT/VF) out-of-hospital cardiac arrest (OHCA) remain poorly defined. The purpose of this..

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Positive results presented from the Australian & New Zealand heart preservation study

Abstract Earlier this month, Professor David Kaye of The Alfred in Melbourne, Australia, presented late breaking science at the American Heart Association (AHA) 2022 meeting in Chicago from an ongoing..

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The Choice of Protamine Sulfate Dosing Regimen for Coronary Artery Bypass Graft Surgery

Abstract Changes in hemodynamics and coagulation hemostasis during the use of protamine sulfate to neutralize heparin in a ratio of 0.5:1 in coronary artery bypass graft surgery have been studied...

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