Abstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and..
Read MoreAbstract Background Acute kidney injury (AKI) usually occurs after cardiopulmonary bypass (CPB) and threatens life without timely intervention. Early assessment and prevention are critical for saving AKI patients. However, numerical..
Read MoreAbstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician..
Read MoreAbstract Introduction Postoperative acute kidney injury (AKI) is a common postoperative complication in cardiac surgery, with varying reported incidences and prognostic factors. Renal hypoperfusion is believed to be a key..
Read MoreAbstract Background The nadir oxygen delivery index (DO2i) during cardiopulmonary bypass (CPB) is reportedly associated with acute kidney injury (AKI) in patients undergoing cardiac surgery. However, there are few reports..
Read MoreAbstract BACKGROUND: Prior studies identified thresholds for mean arterial pressure (MAP <65 mm Hg) and central venous pressure (CVP >12 mm Hg) beyond which risk for cardiac surgery-associated acute kidney..
Read MoreAbstract Objective Acute kidney injury (AKI) affects approximately 30% of patients undergoing cardiac surgery with conventional non-pulsatile cardiopulmonary bypass (CPB). Pulsatile flow has long been proposed for mitigating this complication...
Read MoreAbstract Acute Kidney Injury (AKI) is a common complication after cardiac surgery affecting up to 40% leading to increased morbidity and mortality. To date, there is no specific treatment for..
Read MoreAbstract Background: Postoperative Acute kidney injury (AKI) is a significant concern for cardiac surgery patients with chronic kidney disease (CKD). Effective pharmacological interventions to mitigate these risks are urgently needed...
Read MoreAbstract Objectives To study the association between bleeding and acute kidney injury (AKI). Design Post-hoc study of a randomized trial of 4% albumin versus Ringer's acetate for cardiopulmonary bypass priming..
Read MoreAbstract Acute kidney injury (AKI) is a complex clinical syndrome with a spectrum of clinical manifestations and outcomes (1); characterized by the deterioration of renal function over a period of..
Read MoreAbstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..
Read MoreAbstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..
Read MoreAbstract Background The optimal fluid management strategy for patients undergoing on-pump cardiac surgery was controversial regarding the fluid types. This study aimed to compare the impact of hydroxyethyl starch (HES)..
Read MoreAbstract Background Acute kidney injury (AKI) is a common and serious complication after coronary artery bypass grafting (CABG), significantly affecting patient outcomes. The triglyceride-glucose (TyG) index, a marker of insulin..
Read MoreAbstract Chronic kidney disease (CKD) affects 50% of patients with heart failure. The pathophysiology of CKD in heart failure is proposed to be driven by macrocirculatory hemodynamic changes, including reduced..
Read MoreAbstract Background:Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus,..
Read MoreDay 1 - Organ Transplant Availability, Procurement & OCS Insights Day 2 - NRP (Normothermic Regional Perfusion) Day 3 - Raging Fireside Chat on Transplant Perfusion Challenges..
Read MoreDay 1 - Essential Techniques in Perfusion - RAPP and Hgb Thresholds Day 2 - Mastering Ultrafiltration & Fluid Balance in Perfusion; Essential Techniques & Insights Day..
Read MoreAbstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) results in poor prognosis. Several risk factors for CSA-AKI have been reported, including preoperative creatinine level, cardiopulmonary bypass time, and perioperative blood pressure..
Read MoreAbstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a prevalent complication with poor outcomes, and its early prediction remains a challenging task. Currently available biomarkers for acute kidney injury (AKI)..
Read MoreAbstract Objectives Cardiac surgery–associated acute kidney injury (CSA-AKI) is a common complication with high morbidity and mortality. This study was designed to determine whether adding human albumin to the cardiopulmonary..
Read MoreAbstract Objectives Optimal blood pressure goals during cardiopulmonary bypass (CPB) remain uncertain and new metrics to individualize perfusion targets are needed. Critical closing pressure (Pcrit) is a fundamental property of..
Read MoreAbstract Objectives To investigate the safety and efficacy of ANG-3777, a hepatocyte growth factor mimetic, in mitigating the risk of acute kidney injury (AKI) in patients undergoing cardiac surgery with..
Read MoreAbstract Background Near-infrared spectroscopy (NIRS) enables a non-invasive measurement of tissue oxygen saturation (StO2) in regions illuminated by near-infrared lights. Vascular occlusion test (VOT) serves as a model to artificially..
Read MoreAbstract Acute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income..
Read MoreAbstract Background Acute kidney injury (AKI) is a significant complication in pediatric patients undergoing cardiac surgery. Iron metabolism-related indicators such as ferritin may predict AKI after adult cardiac surgery. However, it..
Read MoreAbstract Background: Acute kidney injury (AKI) occurs in up to 50% of cardiac surgical patients and is often hemodynamically mediated. Point-of-care ultrasound is a non-invasive tool that has the potential..
Read MoreAbstract Haemolysis occurring during cardiac surgery with cardiopulmonary bypass (CPB) is assumed to be a risk factor for postoperative acute kidney injury (AKI). Plasma alpha-1 microglobulin (A1M) may have a..
Read MoreAbstract Background Acute kidney injury (AKI) is a frequent and important complication of cardiac surgery. Decreased perfusion is a key mechanism. This decreased perfusion may be attenuated by intravenous amino..
Read More












