Abstract Importance Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in..
Read MoreAbstract Background Removal of cytokines, chemokines, and microvesicles from the supernatant of allogeneic erythrocytes may help mitigate adverse transfusion reactions. Blood bank–based washing procedures present logistical difficulties; therefore, we tested..
Read MoreAbstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is known to contribute towards the incidence of acute kidney injury (AKI) and peri-operative morbidity and mortality. There are several patient, anaesthetic..
Read MoreTHE CURRENT pandemic owing to coronavirus disease 2019 (COVID-19) has been associated in about 10% to 15% of cases with severe clinical presentations that require admission to hospital. In the..
Read MoreAbstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..
Read MoreAbstract Importance Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in..
Read MoreA team at Duke Health has performed what is believed to be the world’s first partial heart transplant, with the living arteries and valves from a freshly donated heart fused..
Read MoreAbstract Cardiopulmonary bypass (CPB) in infants is associated with morbidity due to systemic inflammatory response syndrome (SIRS). Strategies to mitigate SIRS include management of perfusion temperature, hemodilution, circuit miniaturization, and..
Read MoreAbstract The long-term neurodevelopmental outcome has been a great concern for cardiac surgeons although it is still unclear. There are some risks regarding the neurological and neuropsychological deficits before, during..
Read MoreAbstract The convenience offered by a single-dose cardioplegia strategy is the avoidance of interruption of the flow of surgery and, more importantly, a significant reduction in the cross-clamp time. del..
Read MoreAbstract Background is one of the main natural inhibitors. It is potentiated by heparin, and may be a key component of heparin response, particularly in infants aged <1 year. We sought to..
Read MoreAbstract Background: The use of two diagnostic criteria in the current literature has led to some degree of ambiguity in the precise diagnosis of acute kidney injury in pediatric patients..
Read MoreAbstract Objective Despite an increasing interest in pediatric repair, in children may be unavoidable. The evidence on outcome after pediatric aortic valve replacement is limited and usually reported in small case series...
Read MoreAbstract Objective: To demonstrate positive outcome, to achieve higher flow rates, and to reverse shock more quickly by implementing central extracorporeal membrane oxygenation (ECMO) in children with refractory septic shock. Children..
Read MoreAbstract Because of a severe dysregulation of the host response to infection, septic shock may induce a profound imbalance between oxygen consumption and delivery, which in some cases may be..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) provide respiratory support aimed at gaining time to allow patient’s recovery from hypoxemic and/or hypercapnic respiratory failure, respectively. However, in..
Read MoreAbstract Case Report A 72-year-old man with a tachycardiomyopathy, atrium flutter, and atrial fibrillation underwent an elective radiofrequency ablation procedure. In addition to 5 mg of apixaban twice daily, his..
Read MoreAbstract Introduction: COVID-19 has been associated with increased risk of thrombosis, heparin resistance and coagulopathy in critically ill patients admitted to intensive care. We report the incidence of thrombotic and..
Read MoreAbstract Objective Aortic surgery often causes massive bleeding due to hypofibrinogenemia. Predicting hypofibrinogenemia is useful for developing a hemostasis strategy, including preparing for blood transfusion. We made a formula for..
Read MoreAbstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia..
Read MoreAbstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine proteases (MASP-1, MASP -2), in relation to complications following cardiac surgery in 195 children...
Read MoreAbstract Background: This meta-analysis was performed to review the effects of the addition of modified ultrafiltration (MUF) and conventional ultrafiltration (CUF) to CUF alone on postoperative hemoglobin, surgical and ultrafiltration..
Read MoreAbstract OBJECTIVES Cardiopulmonary bypass in cardiac surgery has been associated with several deleterious effects including haemodilution and systemic inflammation. Modified ultrafiltration (MUF) has been well established in paediatric cardiac surgery..
Read MoreAbstract Background Heparin dosage for anticoagulation during cardiopulmonary bypass (CPB) is commonly calculated based on the patient's body weight. The protamine–heparin ratio used for heparin reversal varies widely among institutions..
Read MoreAbstract Rationale: Recent pediatric studies suggest a survival benefit exists for higher-volume extracorporeal membrane oxygenation (ECMO) centers. Objectives: To determine if higher annual ECMO patient volume is associated with lower..
Read MoreThis case reports on a 7-month-old male pediatric patient (known pre-existing conditions: trisomy 21 (also known as Downs syndrome), aortic isthmus stenosis, atrioventricular septal defect (AVSD) Rastelli type C), who..
Read MoreThis case reports on a 13-year-old male patient who presented to hospital with fever (38.9°), reduced general condition, vomiting and pain in his limbs. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-pediatric-patient-with-severe-rhabdomyolysis-in-the-context-of-a-SARS-CoV-2-infection_compressed.pdf" title="Use of CytoSorb..
Read MoreThe case study reports on a 16-year-old girl, who presented to the hospital with syncope and fever (39°C), tachycardia, complaints of chest pain and coughing after fainting at home. ..
Read MoreThis case reports on a 2-year-old male patient (weight 12 kg), who was admitted to the children‘s outpatient department with anuria, bloody diarrhea, anemia and severe edema (anasarca). [pdf-embedder..
Read MoreThe following case study reports on a 13-year-old pediatric patient (body weight 45 kg) who was admitted to our hospital due to a deterioration in his clinical condition, after he..
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