Archives

thumbnail
0 comment

Anatomy of the Functionally Univentricular Heart

Abstract The world of pediatric cardiac surgery and cardiac surgery as a whole lost one of the great pioneers with the passing, at the beginning of 2018, of Francis Fontan...

Read More
thumbnail
0 comment

Cardioplegia practice in paediatric cardiac surgery: a UK & Ireland survey

Abstract Introduction: Many techniques are available for cardioplegic arrest in children, but there is a lack of late phase clinical trials to guide practice. We surveyed paediatric cardiac surgeons and..

Read More
thumbnail
0 comment

Pediatric extracorporeal membrane oxygenation (ECMO): a guide for radiologists

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment for pediatric patients with respiratory and/or cardiac failure. The ECMO circuit oxygenates and sometimes pumps the blood, effectively replacing lung and/or..

Read More
thumbnail
0 comment

The Starling Relationship and Veno-Arterial ECMO: Ventricular Distension Explained

Abstract The use of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) to support patients with acute heart failure has been associated with ventricular distension and pulmonary edema, the mechanism of which..

Read More
thumbnail
0 comment

Albumin 5% Versus Crystalloids for Fluid Resuscitation in Children After Cardiac Surgery*

Abstract Objectives:  To determine the clinical benefit of using colloids versus crystalloids for volume resuscitation in children admitted after cardiac surgery. Design:  Retrospective pre-/postintervention cohort study. Setting:  Stollery Children’s Hospital..

Read More
thumbnail
0 comment

Feasibility of autologous intraoperative blood collection and retransfusion in small children with complex congenital heart defects undergoing cardiopulmonary bypass

Abstract Introduction Allogeneic blood product transfusion is common in pediatric patients undergoing cardiopulmonary bypass although it is associated with an increased risk for adverse events. Furthermore, numerous donor exposures may..

Read More
thumbnail
0 comment

Continuous cytokine haemoadsorption incorporated into a venoarterial ECMO circuit for the management of postcardiotomy cardiogenic and septic shock – a…

Abstract Introduction: The acute surgical treatment of infective endocarditis (IE) carries a high risk of postoperative mortality. Most complications are linked to uncontrolled sepsis and inflammatory processes. Cytokine haemoadsorption is..

Read More
thumbnail
0 comment

Cardiac Surgery–Associated Kidney Injury in Children and Renal Oximetry

Abstract Objectives:  Cardiac surgery–associated acute kidney injury is common in children and associates with negative outcomes. Novel interventions to reduce cardiac surgery–associated acute kidney injury require knowledge of its pathophysiology...

Read More
thumbnail
0 comment

Pre-operative level of FGF23 predicts severe acute kidney injury after heart surgery in children

Abstract Background Early detection of acute kidney injury (AKI) after cardiac surgery has improved recently with the discovery and validation of novel urinary biomarkers. However, objective tools to predict the..

Read More
thumbnail
0 comment

Anticoagulation with VADs and ECMO: walking the tightrope

Abstract The evolution of devices for mechanical circulatory support (MCS), including ventricular assist devices (VADs) for patients with heart failure and extracorporeal membrane oxygenation (ECMO) for patients with acute cardiac..

Read More
thumbnail
0 comment

Addressing the challenges of ECMO simulation

Abstract Introduction/Aim: The patient’s condition and high-risk nature of extracorporeal membrane oxygenation (ECMO) therapy force clinical services to ensure clinicians are properly trained and always ready to deal effectively with..

Read More
thumbnail
0 comment

A Table Mounted Cardiopulmonary Bypass System for Pediatric Cardiac Surgery

Abstract Systemic inflammatory response and  are prominent factors associated with  and result in increased morbidity and mortality in children. Miniaturized systems have evolved to decrease such effects and restrict use of blood..

Read More
thumbnail
0 comment

Albumin priming improves the efficiency of the Minntech HPH Jr. hemoconcentrator

Abstract The desired use of the HPH Jr. is optimal due to the low priming volume; however, the lower rate of volume removal necessitates utilization of a larger hemofilter. Larger..

Read More
thumbnail
0 comment

A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients

Summary Background Blood transfusion has well‐documented adverse effects. As part of a blood conservation initiative at our center, we began routine use of cell saver for all congenital heart surgery..

Read More
thumbnail
0 comment

Procalcitonin to stop antibiotics after cardiovascular surgery in a pediatric intensive care unit—The PROSACAB study

Abstract Introduction and objective Children admitted to the pediatric intensive care unit after cardiovascular surgery usually require treatment with antibiotics due to suspicion of infection. The aim of this study..

Read More
thumbnail
0 comment

Editorial: Improving Extracorporeal Life Support Outcomes in Children

Abstract Extracorporeal life support (ECLS, also known as extracorporeal membrane oxygenation or ECMO) emerged in the 1970s as a potentially useful life-support therapy for refractory cardiac or respiratory failure in..

Read More
thumbnail
0 comment

Factors involved in initiation and regulation of complement lectin pathway influence postoperative outcome after pediatric cardiac surgery involving cardiopulmonary bypass

Abstract Congenital heart disease (CHD) often requires surgical intervention, and is sometimes associated with life-threatening post-operative complications. We have investigated some factors of the innate immune system involved in the..

Read More
thumbnail
0 comment

Switching to Centrifugal Pumps May Decrease Hemolysis Rates Among Pediatric ECMO Patients

Abstract Recent advances in ECLS technology have led to the adoption of centrifugal pumps for the majority of patients worldwide. Despite several advantages of centrifugal pumps, they remain controversial because..

Read More
thumbnail
0 comment

Audit of transfusion of blood products in paediatric congenital heart surgery on cardiopulmonary bypass

Abstract Background: Cardiac surgery is associated with peri-operative bleeding, which may result in the need for blood transfusion, particularly in paediatric congenital cardiac surgery on cardiopulmonary bypass (CPB). There is..

Read More
thumbnail
0 comment

Functional Performance of Different Venous Limb Options in Simulated Neonatal/Pediatric Cardiopulmonary Bypass Circuits

Abstract Objective: Hemodilution is a concern in cardiopulmonary bypass (CPB). Using a smaller dual tubing rather than a single larger inner diameter (ID) tubing in the venous limb to decrease..

Read More
thumbnail
0 comment

Comparison of the Coagulation Effect Achieved by OctaplasLG Versus Fresh Frozen Plasma in Pediatric Cardiac Surgical Patients

Abstract OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have..

Read More
thumbnail
0 comment

Predictors of Poor Outcomes in Pediatric Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides respiratory and hemodynamic support to pediatric patients in severe cardiac failure. We aim to identify risk factors associated with poorer outcomes in..

Read More
thumbnail
0 comment

The use of acute normovolemic hemodilution in paediatric cardiac surgery

Abstract Background Acute normovolemic hemodilution (ANH) is considered safe and effective in decreasing perioperative transfusion in paediatric populations undergoing high blood‐loss surgeries. We determined the association between ANH and the..

Read More
thumbnail
0 comment

Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer’s chase technique – a…

Abstract Introduction: Residual pump blood from the cardiopulmonary bypass (CPB) circuit is often collected into an infusion bag (IB) and re-transfused. An alternative is to chase the residual blood into..

Read More
thumbnail
0 comment

Optimizing patient care and outcomes through the congenital heart center of the 21st century

Abstract Pediatric cardiovascular services are responding to the dynamic changes in the medical environment, including the business of medicine. The opportunity to advance our pediatric cardiology field through collaboration is..

Read More
thumbnail
0 comment

Cerebral near‐infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults

Background Various techniques have been employed for the early detection of perioperative cerebral ischaemia and hypoxia. Cerebral near‐infrared spectroscopy (NIRS) is increasingly used in this clinical scenario to monitor brain..

Read More
thumbnail
0 comment

Influence of the type of congenital heart defects on epithelial lining fluid composition in infants undergoing cardiac surgery with cardiopulmonary…

Abstract Background In children with congenital heart disease (CHD), altered pulmonary circulation compromises gas exchange. Moreover, pulmonary dysfunction is a complication of cardiac surgery with cardiopulmonary bypass (CPB). No data..

Read More
thumbnail
0 comment

Plasma levels of alarmin HNPs 1–3 associate with lung dysfunction after cardiac surgery in children

ABSTRACT Background Early onset of lung injury is considerable common after cardiac surgery and is associated with increasing in morbidity and mortality, but current clinical predictors for the occurrence of..

Read More
thumbnail
0 comment

An Absorbable Hydrogel Spray Reduces Postoperative Mediastinal Adhesions After Congenital Heart Surgery

Abstract Background Adhesions encountered during reoperative cardiac surgery can prolong operative time and increase operative risk. The purpose of this clinical study was to investigate the antiadhesion property of a..

Read More
thumbnail
0 comment

Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model

Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..

Read More