Abstract Minimally invasive extracorporeal technologies (MiECT) are in great expansion in the literature and have an impact in adult cardiac surgery, however, a future challenge will be to expand MiECT..
Read MoreAbstract This is an updated, comprehensive and practical guideline for healthcare providers providing care to children and young adults with pulmonary hypertension (PH) and pulmonary vascular disease (PVD). Methodology included..
Read MoreAbstract Background Thromboelastography (TEG) predicts bleeding in pediatric patients undergoing cardiac surgery. We hypothesize that TEG parameters at rewarming correlate with post-protamine values and that rewarming TEG is associated with..
Read MoreAbstract To evaluate the effectiveness of retrograde autologous priming (RAP) based on miniaturized cardiopulmonary bypass (CPB) circuit in children undergoing open heart surgery. We performed a retrospective analysis of all..
Read MoreAbstract Objective: To investigate whether the miniaturized cardiopulmonary bypass (CPB) system decreased the usage of ultrafiltration (UF), and to explore whether the non-UF with miniaturized CPB strategy could get..
Read MoreAbstract Great Ormond Street Hospital (GOSH) and Royal Papworth Hospital (RPH) have collaborated to introduce a world-first paediatric heart transplant technique that has successfully expanded the donor pool and increased..
Read MoreAbstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...
Read MoreAbstract Objectives: To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. Design: ..
Read MoreLa pandemia del covid 19 ha impactado enormemente en nuestras vidas, cambiando modelos sociales, económicos y sanitarios. La información es desbordante, cambiante, instantánea, catastrófica unas veces, anecdótica otras, muchas veces..
Read MoreAbstract OBJECTIVE This study aims to describe the population pharmacokinetics and pharmacodynamic target attainment of meropenem in critically ill children. METHODS The study involved a retrospective medical record review from..
Read MoreAbstract Hypoplastic left heart syndrome (HLHS) is a congenital heart defect that requires 3-stage cardiac surgical treatment and multidirectional specialist care. The condition of newborns in the first postoperative days..
Read MoreAbstract Introduction: Cardiopulmonary bypass (CPB) can cause stress response that increases levels of cytokine and catecholamine in plasma, resulting in hyperglycemia. In adults, it has been demonstrated that remifentanil infusion..
Read MoreAbstract OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) is a lifesaving but expensive therapy in terms of financial, technical and human resources. We report our experience with a ‘basic’ ECMO support model,..
Read MoreAbstract Background Coagulopathy is a major problem in surgery for cyanotic congenital heart disease. Tranexamic acid has been used both topically and systemically and plays a vital role in pediatric..
Read MoreAbstract Abstract: Here we report two cases of extracorporeal membrane oxygenation (ECMO) support in pediatric patients following orthotopic heart transplantation due to low cardiac output and inability to separate from..
Read MoreAbstract Background Survival of children experiencing cardiac arrest refractory to conventional cardiopulmonary resuscitation (CPR) is very poor. We sought to examine current era outcomes of extracorporeal CPR (ECPR) support for..
Read MoreAbstract OBJECTIVES This study investigates the effects of high glucose content on patients undergoing cold crystalloid versus cold blood cardioplegia in terms of early clinical results, functional myocardial recovery and..
Read MoreAbstract The provision of continuous renal replacement therapies (CRRT) to small children has generally required the adaptation of adult machines and modified operational characteristics. CRRT prescription for younger and smaller..
Read MoreAbstract Background Each year in the UK, ≈3000 children undergo major cardiac surgery requiring cardiopulmonary bypass. Approximately 40 % of these experience excessive bleeding necessitating red cell transfusion or treatment with..
Read MoreAbstract Background A change of serum lactate concentrations appeared to be useful for predicting outcomes in various acute ill settings. However, there is little information on intraoperative change of lactate..
Read MoreExtracorporeal membrane oxygenation (ECMO) should be considered in patients in whom a reversible pathology is known or suspected, and in whom providing ECMO poses less risks than not providing extracorporeal..
Read MorePediatric population have been affected by the Coronavirus disease 2019 (COVID-19) to a much smaller scale compared with the adult population. The severity of the disease is variable ranging from..
Read MoreThis is an updated guideline from the Extracorporeal Life Support Organization (ELSO) for the role of extracorporeal membrane oxygenation (ECMO) for patients with severe cardiopulmonary failure due to coronavirus disease..
Read MoreWhy Consider ECPR for Cardiopulmonary Arrest in Children? Because Conventional CPR may not be Sufficient to Optimize Outcomes in all Pediatric Cardiopulmonary Arrests Situations Survival rates with good neurologic outcomes..
Read MoreAbstract Introduction: The use of therapeutic hypothermia during neonatal extracorporeal membrane oxygenation (ECMO) as a neurologic protective strategy has gained interest among clinicians despite limited data. Our objective is to..
Read MoreAbstract Over the years, there have been many innovations that have come and gone. It is not often that a single idea dramatically changes how critical care is delivered. Since..
Read MoreAbstract Introduction: Veno-venous extracorporeal membrane oxygenation (vvECMO) used for respiratory support is associated with clinical bleeding in at least one third of patients. Mechanisms promoting bleeding, like acquired von Willebrand..
Read MoreAbstract Objectives The authors hypothesized that transfusion of blood products in neonates and infants undergoing high-risk cardiac surgery in the absence of intraoperative coagulation monitoring increases the risk of thrombotic..
Read MoreAbstract Cardiac arrest in patients on mechanical support is a new phenomenon brought about by the increased use of this therapy in patients with end-stage heart failure. This American Heart..
Read MoreAbstract Background Femoral venoarterial (VA-ECMO) is widely used to maintain blood flow in patients with . However, retrograde blood flow increases left ventricular (LV) afterload during femoral VA-ECMO. Additional support by means..
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