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The association between end-tidal carbon dioxide and arterial partial pressure of carbon dioxide after cardiopulmonary bypass pumping in cyanotic children

Abstract Introduction: Evidence suggests the high capability of non-invasive assessment of the End-tidal carbondioxide (ETCO2) in predicting changes in arterial carbon dioxide pressure (PCO2) following major surgeries in children. We aimed..

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A systematic review of the evidence supporting post-operative antithrombotic use following cardiopulmonary bypass in children with CHD

Abstract Objectives:To determine the optimal antithrombotic agent choice, timing of initiation, dosing and duration of therapy for paediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Methods:We used PubMed and EMBASE..

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Evaluating the Impact of Cardiopulmonary Bypass Priming Fluids on Bleeding After Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract Objectives Cardiopulmonary bypass (CPB) predisposes young children to coagulopathy. The authors evaluated possible effects of CPB priming fluids on perioperative bleeding in pediatric cardiac surgery. Design Meta-analysis and systematic..

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Extracorporeal Life Support Organization Guideline for Transport and Retrieval of Adult and Pediatric Patients with ECMO Support

Abstract Disclaimer:  This extracorporeal life support organization guideline describes the preparation for and undertaking of transport and retrieval of patients on extracorporeal membrane oxygenation (ECMO). The guideline describes useful and..

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The Fundamental Skills and Deconstructed Sub-Steps of Pediatric Cardiopulmonary Bypass

Abstract Perfusion education programs use simulation to provide students with clinical skills prior to entering the operating room. To teach the psychomotor execution of skills in a simulation lab requires..

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Effect of CPB Glucose Levels on Inflammatory Response After Pediatric Cardiac Surgery

Abstract Background: Systemic inflammatory response syndrome (SIRS) is a common complication after cardiac surgery. There are no definite optimal glycemic threshold for pediatric patients receiving open-heart surgery with CPB. The..

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Plasma and Platelet Transfusions Strategies in Neonates and Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass or Neonates and Children Supported…

Abstract Objectives:  To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or..

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Association of Arterial Hyperoxia With Outcomes in Critically Ill Children

Abstract Importance  Oxygen supplementation is a cornerstone treatment in pediatric critical care. Accumulating evidence suggests that overzealous use of oxygen, leading to hyperoxia, is associated with worse outcomes compared with patients..

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Extracorporeal Membrane Oxygenation for Septic Shock in Children

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue treatment used in children and adults with reversible cardiorespiratory failure. The role of ECMO is not fully established in pediatric sepsis. In..

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ELSO Guidelines for Adult and Pediatric Extracorporeal Membrane Oxygenation Circuits

Abstract This guideline describes the ECMO circuit for all patient populations. These guidelines describe safe practice based on extensive experience and are considered consensus guidelines. These guidelines are not intended..

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Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation

Abstract Objectives:  Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of..

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2021 ELSO Adult and Pediatric Anticoagulation Guidelines

Abstract Anticoagulation is necessary for most pediatric and adult extracorporeal membrane oxygenation (ECMO) patients to prevent circuit clotting. Inherently, the most common side effect of anticoagulation is bleeding. Anticoagulation during..

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Somatic Support with Veno-venous ECMO in a Pregnant Woman with Brain Death: A Case Report

Abstract Supporting homeostasis in a pregnant woman with brain death to achieve fetal viability is called somatic support. We present a case of young pregnant woman at 21 weeks’ gestation..

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Vacuum-assisted venous drainage, angel or demon: PRO?

Abstract Vacuum-assisted venous drainage (VAVD) was proposed to optimize venous drainage during bypass through femoral venous cannulation. It is currently used in both adult and pediatric surgery when siphon gravity..

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Antithrombin III infusion improves anticoagulation in congenital diaphragmatic hernia patients on extracorporeal membrane oxygenation

Abstract Purpose Achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage remains challenging. The use of antithrombin III (AT-III) for this purpose has been..

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Use of Extracorporeal Membrane Oxygenation in Acutely Poisoned Pediatric Patients in United States

Abstract Objectives:  To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design:  Retrospective cohort study. Setting: ..

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Delirium in Children After Cardiac Bypass Surgery

Abstract Background Delirium is acute brain dysfunction associated with serious illness. Emerging data indicate that delirium occurs in greater than 20% of children in pediatric intensive care units. Cardiac bypass..

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Pediatric Extracorporeal Life Support Transport in Western Canada

Abstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes..

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Le prime linee guida per l'uso dell'ECMO nei pazienti pediatrici sottoposti a trapianto di cellule staminali ematopoietiche

Abstract È l’Ospedale Pediatrico Bambino Gesù, in collaborazione con 5 società scientifiche internazionali, a mettere per la prima volta a disposizione di rianimatori e oncoematologi le Linee Guida per il trattamento con ossigenazione extracorporea..

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Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement

Abstract Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements..

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Left Heart Decompression on Veno-Arterial Extracorporeal Membrane Oxygenation in Children With Dilated Cardiomyopathy and Myocarditis: An Extracorporeal Life Support Organization…

Abstract OBJECTIVES:  To describe the association between left heart decompression on veno-arterial extracorporeal membrane oxygenation and survival in patients with myocarditis and dilated cardiomyopathy. The secondary outcome is to study..

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Pediatric ECMO: unfavorable outcomes are associated with inflammation and endothelial activation

Abstract Background Inflammatory and endothelial activation responses during extracorporeal membrane oxygenation (ECMO) support in children are poorly understood. In this study, we aimed to determine if circulating inflammatory, endothelial activation,..

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Efficacy and safety of aprotinin in paediatric cardiac surgery

Abstract BACKGROUND  The relicensing of aprotinin in Europe and Canada has stimulated discussions on its usefulness in paediatric cardiac surgery. OBJECTIVE  To systematically evaluate the available evidence on the efficacy..

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The effect of selective cerebral perfusion on cerebral versus somatic tissue oxygenation during aortic coarctation repair in neonates and infants

Abstract Background Suboptimal tissue perfusion and oxygenation may be the root cause of certain perioperative complications in neonates and infants having complicated aortic coarctation repair. Practical, effective, and real-time monitoring..

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Impact of Arterial Carbon Dioxide and Oxygen Content on Cerebral Autoregulation Monitoring Among Children Supported by ECMO

Abstract Background Cerebral autoregulation (CA) impairment is associated with neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Severe variations of arterial CO2 (PaCO2) and O2 (PaO2) tension after ECMO onset..

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How Dose Body Water Composition Change Around Cardiopulmonary Bypass Surgery of Children with Congenital Heart Disease? -Assessing by Bioelectrical Impedance…

Abstract Introduction: Although the management of body water balance on cardiac surgery with cardiopulmonary bypass (CPB), especially in children, is essential, little is known how body water composition changes around CPB...

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The Anesthesiologist’s Perspective and Experience in Global Congenital Cardiac Surgery: Results of a Survey of the Congenital Cardiac Anesthesia Society…

Abstract Anesthesiologists are important components of volunteer teams which perform congenital cardiac surgery in low-resource settings throughout the world, but limited data exist to characterize the nature and breadth of..

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Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study

Abstract OBJECTIVES:  Patients in the pediatric cardiac ICU are frequently exposed to pharmacologic and environmental factors that predispose them to sleep disturbances and may increase the risk of delirium. In..

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Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine

Abstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...

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