Abstract Outcomes of pediatric patients who received extracorporeal life support (ECLS) for COVID-19 remain poorly described. The aim of this multi-institutional retrospective observational study was to evaluate these outcomes and..
Read MoreAbstract Obesity is associated with an overall increased risk of morbidity and mortality. However, in patients with critical illness, sepsis, and acute respiratory distress syndrome, obesity may be protective, termed..
Read MoreAbstract Despite ECMO being a well-accepted and established life-saving support for newborns, prematurity (<34 weeks of gestation) and low birth weight <2.0 kg are still considered relative contraindications due to..
Read MoreAbstract Introduction and Methods We examined the relationship between 24-h pre- and post-cannulation arterial oxygen tension (PaO2) and arterial carbon dioxide tension (PaCO2) and subsequent acute brain injury (ABI) in..
Read MoreAbstract Primary graft dysfunction (PGD) after cardiac transplantation is a devastating complication with increasing frequency lately in the setting of donation after circulatory death (DCD). Severe PGD is commonly treated..
Read MoreAbstract Regional tissue oxygen saturation (rSO2) monitoring through near-infrared spectroscopy (NIRS) has been reported as a non-invasive strategy to estimate the adequacy of matching between oxygen delivery (DO2) and oxygen..
Read MoreAbstract Background strategy, vasopressors, and hemolysis are important physiological factors that influence in (ECMO). We hypothesized these factors influence the discrepancy between measured by (Spo2) and (Sao2) on ECMO. Methods We retrospectively analyzed adults (aged ≥18..
Read MoreAbstract Background: Venoarterial extracorporeal membrane oxygenation (VA ECMO) is an emergency procedure performed across various specialties. These conditions present barriers to education and assessment of competency. Checklists and simulation may be..
Read MoreAbstract Background (FXII) is a multifunctional capable of activating thrombotic and inflammatory pathways. FXII has been linked to thrombosis in (ECMO), but the role of FXII in ECMO-induced inflammatory complications has not..
Read MoreAbstract Purpose Ultraprotective ventilation in (ARDS) patients with veno-venous (VV ECMO) reduces mechanical power (MP) through changes in positive end-expiratory pressure (PEEP); however, the optimal approach to titrate PEEP is unknown. This..
Read MoreAbstract Background: Since 2013, the cardiac intensive care unit (CICU) at Children's National has conducted annual extracorporeal membrane oxygenation cardiopulmonary resuscitation (ECPR) simulations that focus on team dynamics, room setup, and..
Read MoreAbstract BACKGROUND Extracorporeal life support (ECLS) is increasingly used in the treatment of infarct-related cardiogenic shock despite a lack of evidence regarding its effect on mortality. METHODS In this multicenter..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and anticoagulation systems in a patient, leading..
Read MoreAbstract Extracorporeal support modalities are highly prothrombotic. Anticoagulation is frequently used for patients receiving Continuous Renal Replacement Therapy (CRRT), Molecular Adsorbent Recirculating System (MARS), and Extracorporeal Membrane Oxygenation (ECMO). The..
Read MoreAbstract Background Extracorporeal life support (ECLS) has extensive applications in managing patients with acute cardiac and pulmonary failure. Two primary modalities of ECLS, cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation..
Read MoreAbstract This study investigated changes in coagulation and associations with occurrence of bleeding and thrombosis during extracorporeal membrane oxygenation (ECMO) therapy. The study included 100 adult ECMO-patients. Standard coagulation parameters,..
Read MoreAbstract As the key component of extracorporeal membrane oxygenation (ECMO), artificial lung membranes have low gas permeability and plasma leakage problems, and the contact between membrane materials and blood can..
Read MoreAbstract Objective (FXII) is a multifunctional capable of activating thrombotic and inflammatory pathways. FXII has been linked to thrombosis in (ECMO), but the role of FXII in ECMO-induced inflammatory complications has not..
Read MoreAbstract Drainage insufficiency is a common phenomenon during extracorporeal life support, related to a variable and potentially multiple etiologies. Being associated with impaired extracorporeal blood flow (EBF), so with impaired..
Read MoreAbstract Background In the field of extracorporeal life support (ECLS), the rapid influx of novel technologies and innovative techniques presents an ongoing challenge for professionals to stay informed about these..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is an important rescue therapy method for the treatment of severe hypoxic lung injury. In some cases, oxygen saturation and oxygen partial pressure in the..
Read MoreAbstract The aim of this study was to explore the association between arterial return cannula diameter and hemolysis during peripheral VA ECMO. We identified 158 adult patients who received peripheral..
Read MoreAbstract Background Extubation during extracorporeal oxygenation (ECMO) in severe acute respiratory distress syndrome(ARDS) has not been well studied. Despite the potential benefits of this strategy, weaning from ECMO before libera‑tion..
Read MoreAbstract The escalating concern of obesity in the United States isn’t merely a statistic; it’s a palpable crisis. As of 2017-2018, the CDC noted that . The ramifications of this startling..
Read MoreDynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO
Read MoreAbstract Introduction: Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series. We..
Read MoreAbstract Background Venoarterial (VA-ECMO) is increasingly used with despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..
Read MoreAbstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced..
Read MoreAbstract Rationale: Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider obesity a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support,..
Read MoreAbstract In patients with acute MI complicated by cardiogenic shock (AMICS) who are slated to undergo early revascularization, routine use of extracorporeal membrane oxygenation (ECMO) doesn’t reduce 30-day mortality. The..
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