Archives

thumbnail
0 comment

Commercial and novel anticoagulant ECMO coatings: a review

Abstract Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and anticoagulation systems in a patient, leading..

Read More
thumbnail
0 comment

Efficacy of Prostacyclin Anticoagulation in Critically Ill Patients Requiring Extracorporeal Support: A Systematic Review and Meta-Analysis

Abstract Extracorporeal support modalities are highly prothrombotic. Anticoagulation is frequently used for patients receiving Continuous Renal Replacement Therapy (CRRT), Molecular Adsorbent Recirculating System (MARS), and Extracorporeal Membrane Oxygenation (ECMO). The..

Read More
thumbnail
0 comment

The effects of nitric oxide on coagulation and inflammation in ex vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

Abstract Background Extracorporeal life support (ECLS) has extensive applications in managing patients with acute cardiac and pulmonary failure. Two primary modalities of ECLS, cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation..

Read More
thumbnail
0 comment

Bleeding patients on extracorporeal membrane oxygenation have reduced platelet aggregation and plasma fibrinogen: a longitudinal observational study

Abstract This study investigated changes in coagulation and associations with occurrence of bleeding and thrombosis during extracorporeal membrane oxygenation (ECMO) therapy. The study included 100 adult ECMO-patients. Standard coagulation parameters,..

Read More
thumbnail
0 comment

Phosphorylcholine/Heparin Composite Coatings on Artificial Lung Membrane for Enhanced Hemo-compatibility

Abstract As the key component of extracorporeal membrane oxygenation (ECMO), artificial lung membranes have low gas permeability and plasma leakage problems, and the contact between membrane materials and blood can..

Read More
thumbnail
0 comment

Factor XII promotes the thromboinflammatory response in a rat model of veno-arterial extracorporeal membrane oxygenation.

Abstract Objective  (FXII) is a multifunctional  capable of activating thrombotic and inflammatory pathways. FXII has been linked to thrombosis in  (ECMO), but the role of FXII in ECMO-induced inflammatory complications has not..

Read More
thumbnail
0 comment

Fibrin and Drainage Insufficiency on Extracorporeal Support: What Came First?

Abstract Drainage insufficiency is a common phenomenon during extracorporeal life support, related to a variable and potentially multiple etiologies. Being associated with impaired extracorporeal blood flow (EBF), so with impaired..

Read More
thumbnail
0 comment

Year in review: Highlights in ECLS Innovation and Technology, Anno 2022-2023

Abstract Background In the field of extracorporeal life support (ECLS), the rapid influx of novel technologies and innovative techniques presents an ongoing challenge for professionals to stay informed about these..

Read More
thumbnail
0 comment

Comparison of Serial and Parallel Connections of Membrane Lungs against Refractory Hypoxemia in a Mock Circuit

Abstract Extracorporeal membrane oxygenation (ECMO) is an important rescue therapy method for the treatment of severe hypoxic lung injury. In some cases, oxygen saturation and oxygen partial pressure in the..

Read More
thumbnail
0 comment

Smaller Return Cannula in Venoarterial Extracorporeal Membrane Oxygenation Does Not Increase Hemolysis: A Single-Center, Cohort Study

Abstract The aim of this study was to explore the association between arterial return cannula diameter and hemolysis during peripheral VA ECMO. We identified 158 adult patients who received peripheral..

Read More
thumbnail
0 comment

Standardized approach for extubation during extracorporeal membrane oxygenation in severe acute respiratory distress syndrome: a prospective observational study

Abstract Background Extubation during extracorporeal oxygenation (ECMO) in severe acute respiratory distress syndrome(ARDS) has not been well studied. Despite the potential benefits of this strategy, weaning from ECMO before libera‑tion..

Read More
thumbnail
0 comment

Groundbreaking NIH Study Reveals: ECMO More Effective for Obese Patients than Previously Thought!

Abstract The escalating concern of obesity in the United States isn’t merely a statistic; it’s a palpable crisis. As of 2017-2018, the CDC noted that . The ramifications of this startling..

Read More
thumbnail
0 comment

Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

Read More
thumbnail
0 comment

Extracorporeal Blood Purification with CytoSorb in 359 Critically Ill Patients

Abstract Introduction: Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series. We..

Read More
thumbnail
0 comment

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

Abstract Background Venoarterial  (VA-ECMO) is increasingly used  with  despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..

Read More
thumbnail
0 comment

Antithrombin III supplementation during neonatal and pediatric extracorporeal membrane oxygenation

Abstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced..

Read More
thumbnail
0 comment

Mortality in Patients with Obesity and ARDS Receiving ECMO: The Multicenter ECMObesity Study

Abstract Rationale: Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider obesity a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support,..

Read More
thumbnail
0 comment

Routine ECMO in AMICS Patients Not Protective: ECLS-SHOCK

Abstract In patients with acute MI complicated by cardiogenic shock (AMICS) who are slated to undergo early revascularization, routine use of extracorporeal membrane oxygenation (ECMO) doesn’t reduce 30-day mortality. The..

Read More
thumbnail
0 comment

Detecting Oxygenator Thrombosis in ECMO: A Review of Current Techniques and an Exploration of Future Directions

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-support technique used to treat cardiac and pulmonary failure, including severe cases of COVID-19 (coronavirus disease 2019) involving acute respiratory distress syndrome. Blood..

Read More
thumbnail
0 comment

Children who suffer cardiac arrest more likely to survive at ECMO capable hospitals

Abstract Children who experience cardiac arrest are one and a half times more likely to survive at a hospital capable of providing the life support system called ECMO, research suggests...

Read More
thumbnail
0 comment

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

Abstract Background Venoarterial  (VA-ECMO) is increasingly used  with  despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..

Read More
thumbnail
0 comment

Micellar Encapsulation of Propofol Reduces its Adsorption on Extracorporeal Membrane Oxygenator (ECMO) Circuit

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass device used on critically ill patients with refractory heart and lung failure. Patients supported with ECMO receive numerous drugs to..

Read More
thumbnail
0 comment

Outcomes of a modified, low-cost, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) for elective, periprocedural support of high-risk percutaneous cardiac interventions:…

Abstract Introduction High-risk procedures in interventional cardiology include a wide spectrum of clinical and anatomical scenarios related to a higher periprocedural morbidity and mortality. The prophylactic use of short-term mechanical..

Read More
thumbnail
0 comment

Pilot Testing of a Lightweight, Pulmonary Assist System in an Ambulatory Sheep Model of Destination Therapy Respiratory Support

Abstract A new, lightweight (2.3 kg), ambulatory pulmonary assist system (PAS) underwent preliminary evaluation in ambulatory sheep. The PAS was purposefully designed for long-term extracorporeal respiratory support for chronic lung..

Read More
thumbnail
0 comment

A Simple Formula for Predicting Ventricular Distension With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Left ventricular (LV) distention is a known complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO) due to increased afterload stress. The consequences of LV distension include elevated pulmonary venous pressures leading to pulmonary edema and increased wall..

Read More
thumbnail
0 comment

Bridging the gap: safety and outcomes of intensivist-led ECMO retrievals

Abstract Purpose: Most extracorporeal membrane oxygenation (ECMO) cannulations are performed by cardiothoracic surgeons (CTS). Due to an increase in utilization of ECMO and limited availability of CTS, there is a mismatch..

Read More
thumbnail
0 comment

Transfusion of red blood cells in venoarterial extracorporeal membrane oxygenation: A multicenter retrospective observational cohort study

Abstract Background Evidence-based recommendations for transfusion in patients with venoarterial extracorporeal membrane oxygenation (VA ECMO) are scarce. The current literature is limited to single-center studies with small sample sizes, therefore..

Read More
thumbnail
0 comment

Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial…

Abstract Objectives:  Peripheral venoarterial extracorporeal membrane oxygenation (ECMO) with femoral access is obtained through unilateral or bilateral groin cannulation. Whether one cannulation strategy is associated with a lower risk for limb ischemia remains unknown...

Read More
thumbnail
0 comment

Use of Perioperative Extracorporeal Membranous Oxygenation in Pulmonary Endarterectomy Cases: A Systematic Review and Meta-Analysis

Abstract Introduction Pulmonary endarterectomy (PEA) is known to be a curative intervention for chronic thromboembolic pulmonary hypertension (CTEPH). Its complications include endobronchial bleeding, persistent pulmonary arterial hypertension, right ventricular failure,..

Read More
thumbnail
0 comment

Naming and Unnaming in the Extracorporeal Membrane Oxygenation Literature

Abstract We are grateful for the readers’ interest and suggestions relevant to our original contribution entitled “Pulmonary Artery Dual-Lumen Cannulation Versus Two Cannula Percutaneous Extracorporeal Membrane Oxygenation Configuration in Right..

Read More