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Conventional Cardiopulmonary Resuscitation Versus Extracorporeal Membrane Oxygenation-Assisted CPR in Children: A Retrospective Analysis of Outcomes and Factors Associated with Conversion…

Abstract Background/Objectives: Conventional cardiopulmonary resuscitation (CCPR) has been the foundational resuscitation approach for decades. Where CCPR is unsuccessful, extracorporeal membrane oxygenation-assisted CPR (ECPR) may improve outcomes. Predicting failure of CCPR..

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Access to hospitals with extracorporeal membrane oxygenation capabilities as a potential of driver of disparities

Abstract Extracorporeal membrane oxygenation (ECMO) is a rapidly growing resource for the most critically ill patients with respiratory and/or circulatory failure. [1,2] ECMO is one of the most resource intensive..

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Flow Mode-Dependent Regulation of von Willebrand Factor Degradation in Mechanical Circulatory Support

Abstract Background Among patients reliant on continuous-flow (CF) mechanical circulatory support devices, bleeding is primarily caused by an acquired von Willebrand factor (vWF) deficiency, precipitated by the high shear stress..

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Increased VA-ECMO Pump Speed Reduces Left Atrial Pressure: Insights from a Novel Biventricular Heart Model

Abstract Background and aims:  The effect of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) on left atrial pressure (LAP) in the presence of interventricular interaction and the Frank–Starling mechanism is unknown. We..

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Effect of Respiratory Support Type and Total Duration on Weaning From Venovenous Extracorporeal Membrane Oxygenation in COVID-19 Patients

Abstract Background: We evaluated the impact of noninvasive respiratory support (NRS) and invasive mechanical ventilation duration before venovenous extracorporeal membrane oxygenation (VV-ECMO) on weaning from venovenous ECMO and survival.   Methods: In..

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Vascular Closure Device vs Open Decannulation for Femoral Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Traditional decannulation of femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) involves femoral cutdown. Percutaneous methods have been developed, but data supporting their use are limited. This study sought..

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Venoarterial Extracorporeal Membrane Oxygenation Therapy in Patients with Sickle Cell Disease: Case Series and Review for Intensive Care Physicians

Abstract Sickle cell disease (SCD) is associated with substantial morbidity and early mortality in afflicted adults. Cardiopulmonary complications that occur at increased frequency in SCD such as pulmonary embolism, pulmonary..

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Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation

Abstract Purpose Sparse data exist on delirium in VA-ECMO. We aim to describe the characteristics, risk factors, and outcomes of delirium in VA-ECMO. Methods We retrospectively reviewed adults’s electronic medical..

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Redefining ECMO cannulation: A case for TEE-guided VP ECMO and flotation catheter

Abstract Venopulmonary ECMO (VP ECMO) is an advanced support strategy for patients with severe respiratory failure and right ventricular (RV) dysfunction, providing pulmonary protection by oxygenating blood and unloading the..

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Trauma-related psychopathologies after extracorporeal membrane oxygenation support: A systematic review and meta-analysis

Abstract Extracorporeal Membrane Oxygenation (ECMO) use is associated with substantial psychiatric morbidity in patients and their families. This systematic review and meta-analysis quantifies the prevalence of post-traumatic stress disorder (PTSD),..

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Prolonged Use of Extracorporeal Membrane Oxygenators for COVID-19–Associated Acute Respiratory Distress Syndrome: A Retrospective Analysis

Abstract Whether an anticoagulation strategy combining bivalirudin and aspirin during extracorporeal membrane oxygenation (ECMO) would prolong oxygenator use is unknown. No clear data exist on oxygenator life span during prolonged..

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Diagnosing Nosocomial Infections During Pediatric Extracorporeal Membrane Oxygenation

Abstract Nosocomial infections are one of the most frequent complications of extracorporeal membrane oxygenation (ECMO) and are associated with increased mortality (). Bloodstream infections present a particular problem because of..

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Sepsis-Extracorporeal Membrane Oxygenation Score in Patients Receiving Extracorporeal Membrane Oxygenation Support for Sepsis

Abstract Predictive scoring systems for adult patients receiving extracorporeal membrane oxygenation (ECMO) support for sepsis have not been yet reported. Based on the Chinese Society of ExtraCorporeal Life Support (CSECLS)..

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Practical Considerations for Extracorporeal Membrane Oxygenation Use During Orthotopic Liver Transplantation

Abstract Patients undergoing liver transplantation infrequently require extracorporeal membrane oxygenation (ECMO) support. However, when ECMO is required in the peritransplant period, several key considerations are required to maximize the efficacy..

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Fluid management in adult patients undergoing venoarterial extracorporeal membrane oxygenation: A scoping review

Abstract Background The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a cardiocirculatory support has tremendously increased in critically ill patients. Although fluid therapy is an essential component of the..

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Carboxyhemoglobin and Methemoglobin as Biomarkers of Hemolysis and Mortality in Acute Respiratory Distress Syndrome Treated by Veno-Venous Extracorporeal Membrane Oxygenation

Abstract BACKGROUND:  Critically ill patients who receive circulatory or respiratory assist using extracorporeal membrane oxygenation (ECMO) may develop hemolysis, which can complicate the delivery of supportive care and be a..

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Total bilirubin as a marker for hemolysis and outcome in patients with severe ARDS treated with veno-venous ECMO

Abstract Background Hemolysis is a common complication in critically ill patients with sepsis, acute respiratory distress syndrome (ARDS) or therapy with extracorporeal membrane oxygenation (ECMO). Heme degradation product bilirubin might..

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Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

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Awake veno-venous extracorporeal membrane oxygenation: practical aspects and considerations

Abstract Veno-venous extracorporeal membrane oxygenation (ECMO) is a life-saving technique in the armamentarium of critical care medicine. It involves extracorporeal blood circulation outside the body, providing temporary respiratory support while..

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Association of carboxyhemoglobin and methemoglobin levels with hemolysis during extracorporeal membrane oxygenation

Abstract Introduction: Hemolysis, characterized by increased carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels, is a complication of extracorporeal membrane oxygenation (ECMO). Methods: This prospective single-center study aimed to investigate the correlation..

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Capillary refill time and tissue oxygen saturation as factors influencing lower limb ischemia in VA-ECMO: a case-control study

Abstract Background and objectives Venous-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a pivotal means for rapid cardiopulmonary support, yet it may result in lower limb ischemia. This study aims to explore..

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The Effect of Extracorporeal Membrane Oxygenation on the Pharmacokinetics of Dexmedetomidine Hydrochloride

Abstract Objectives Our objective was to explore the effects of extracorporeal membrane oxygenation (ECMO) on the pharmacokinetics of dexmedetomidine hydrochloride via vitro and in vivo experiments Design A single-center animal..

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Kidney Injury under Diminished Pulsatile Flow Induced by V-A ECMO in Sheep

Abstract Extracorporeal membrane oxygenation (ECMO) is commonly used for critically ill patients and associated with high rates of kidney injury and mortality. This study aimed to assess the impact of..

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Predictors and outcomes in patients undergoing surgery for acute type A aortic dissection requiring concomitant venoarterial extracorporeal membrane oxygenation support—a…

Abstract OBJECTIVES The study’s aim was to investigate the outcomes and risk factors for mortality in patients undergoing surgery for acute type A aortic dissection receiving concomitant venoarterial extracorporeal membrane..

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Perioperative extracorporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) can act as a bridge to recovery in both pre- and postoperative patients with transposition of the great arteries (TGA). However, literature on its..

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Timing of venoarterial extracorporeal membrane oxygenation in infant cardiac surgery: a single-centre retrospective study of clinical outcomes

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA ECMO) is a critical therapeutic intervention that is commonly used in the management of paediatric patients with congenital heart disease (CHD). This procedure..

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Battlefield mechanical ventilation and extracorporeal membrane oxygenation: A scoping review

Abstract Background Casualties of military conflicts suffer a multitude of injuries, and recent research has documented a significant number develop acute respiratory distress syndrome (ARDS). The present study undertakes a..

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Predictors and outcomes in patients undergoing surgery for acute type A aortic dissection requiring concomitant venoarterial extracorporeal membrane oxygenation support—a…

Abstract OBJECTIVES The study’s aim was to investigate the outcomes and risk factors for mortality in patients undergoing surgery for acute type A aortic dissection receiving concomitant venoarterial extracorporeal membrane..

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Early endovascular reperfusion during extracorporeal support for massive pulmonary embolism

Abstract In massive pulmonary embolism (PE), endovascular therapies and extracorporeal membrane oxygenation (ECMO) are increasingly utilised. However, the impact of combining endovascular therapies with ECMO on shock resolution and clinical recovery remains..

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Post-pericardiectomy ECMO for constrictive pericarditis: a case series and literature review

Abstract Background Pericardiectomy is the curative treatment for constrictive pericarditis, yet postoperative low cardiac output syndrome (LCOS) may occur. The application of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in post-pericardiectomy refractory..

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