Abstract Background: Cardiac surgery with cardiopulmonary bypass (CPB) is associated with impaired renal oxygenation and acute kidney injury. We investigated whether a higher than our standard blood flow during CPB..
Read MoreAbstract Background During cardiopulmonary bypass (CPB), which is frequently utilized in open-heart surgery, the maintenance of circulation in a non-physiological environment may lead to alterations in the properties of circulating..
Read MoreAbstract Introduction Standard “yes/no”' checklists fail to meet their purported goals of enhancing patient safety because they enable inattentive completion and complacency. The mere presence of a check mark is..
Read MoreAbstract Background Despite sternum sparing and without cardiopulmonary bypass, the actual value of minimally invasive coronary surgery (MICS) is still debatable. This study aimed to compare the completeness of revascularization..
Read MoreAbstract Background: Minimally invasive extracorporeal circulation (MiECC) has been introduced to mitigate the inflammatory response and reduce blood transfusion needs compared to conventional cardiopulmonary bypass (CPB) perioperatively. A hybrid system..
Read MoreAbstract BACKGROUND: Current blood pressure management strategies cannot accommodate large interindividual variations in cerebral autoregulation, which may result in inadvertent cerebral ischemia. A novel optical neuromonitoring device was developed to..
Read MoreAbstract Introduction: In cardiopulmonary bypass (CPB), blood circulation is temporarily maintained by an artificial blood-pumping device during cardiac surgery. Worldwide, approximately half of the CPB procedures utilize either centrifugal or..
Read MoreAbstract Background Studies have proved that artery infusion during CPB operations can reduce lung injury led by CPB surgery. This study was undertaken to investigate the effects of HTK solution..
Read MoreAbstract Introduction Increased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs...
Read MoreAbstract Background Cardiopulmonary bypass use during surgery disrupts microcirculation, which can contribute to lung injury, particularly in patients with pulmonary comorbidities. Continuous transcutaneous carbon dioxide (CO2) monitoring assists clinicians to..
Read MoreAbstract Background and Objectives: The aim of this study was to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia (TIVA) on intraocular pressure (IOP) during coronary artery..
Read MoreAbstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary..
Read MoreAbstract OBJECTIVES Current preoperative counselling in neonatal cardiac surgery is mainly focused on the primary procedure. However, other factors must be considered when evaluating the surgical risk of a neonate...
Read MoreAbstract Cardiac surgery with cardiopulmonary bypass (CPB) may lead to many postoperative complications. However, many complications cannot be predicted in time using the current clinical methods, or the prediction is..
Read MoreAbstract BACKGROUND Cardiopulmonary bypass (CPB) is a life-support technology widely used in surgery. Review articles reflect research advances in a certain topic or field within a certain period of time...
Read MoreAbstract Introduction Cardiac surgery in infants often triggers a severe inflammatory response. The role of biomarkers in predicting clinical outcomes in this group of patients has been debated in the..
Read MoreAbstract Background: Population pharmacokinetics (PK) models could provide specific references for the formulation of personal drug delivery protocols, however, there is no population PK study of tranexamic acid (TXA) have been..
Read MoreAbstract Introduction: Indexed oxygen delivery (DO₂i) is a critical parameter in cardiopulmonary bypass (CPB) management. Traditional goal-directed perfusion (GDP) protocols use fixed DO₂i thresholds, typically derived from normothermic conditions. However,..
Read MoreAbstract Purpose Clinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac..
Read MoreAbstract Acute kidney injury (AKI) is a frequent and severe problem following heart surgery, particularly in procedures involving cardiopulmonary bypass (CPB). This research investigates the Randomized Controlled Trial (RCT) on..
Read MoreAbstract Background Delirium is a common neurological complication after cardiac surgery. The purpose of the present study was to analyze the association between hemodynamic fluctuations during cardiopulmonary bypass (CPB) and..
Read MoreAbstract Introduction Imbalance in the redox equilibrium is common in any type of aggression. Cardiopulmonary bypass (CPB) initiation induces metabolic perturbations, and reliable biological monitoring tools for this condition are..
Read MoreAbstract Background Acute kidney injury (AKI) usually occurs after cardiopulmonary bypass (CPB) and threatens life without timely intervention. Early assessment and prevention are critical for saving AKI patients. However, numerical..
Read MoreAbstract OBJECTIVES Peripheral cannula selection in minimally invasive cardiac surgery (MICS) is crucial, as venous drainage limitations during cardiopulmonary bypass (CPB) can impair end-organ perfusion and overall outcomes. This study..
Read MoreAbstract Objective Cardiac arrest happens in 0.7%-5.2% patients after cardiovascular surgery, and cases with asystole or severe bradycardia need timely temporary pacing. However, routine temporary pacing wire insertion in cardiopulmonary..
Read MoreAbstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..
Read MoreAbstract Background: Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are widely used. Previous methods to reduce inflammation have shown inconsistent results. We developed a cytokine adsorption column using polymethyl methacrylate..
Read MoreAbstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..
Read MoreAbstract Introduction Cardiopulmonary bypass (CPB) is essential for cardiac surgery but poses risks, including gaseous micro emboli (GME). While the incidence of stroke—a common clinical consequence of embolism—ranges from 1-5%..
Read MoreAbstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician..
Read More















