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Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study

Abstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..

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Hemoadsorption Treatment of Patients with Acute Infective Endocarditis during Surgery with Cardiopulmonary Bypass – A Case Series

Abstract Introducton: Infective endocarditis is a serious disease condition. Depending on the causative microorganism and clinical symptoms, cardiac surgery and valve replacement may be needed, posing additional risks to patients..

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Treatment of post-cardiopulmonary bypass SIRS by hemoadsorption: a case series

Abstract The use of cardiopulmonary bypass (CPB) in cardiothoracic surgery results in a well-known activation of the immunologic response. In some cases, however, this triggered immunologic response may be excessive,..

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Use of the Hypotension Prediction Index During Cardiac Surgery

Abstract Objective The hypotension prediction index (HPI) is a novel parameter developed by Edwards Lifesciences (Irvine, CA) that is obtained through an algorithm based on arterial pressure waveform characteristics. Past..

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Polypropylene Oxygenators: Risk Of SARS-Cov-2 Contamination in The Operation Theatre?

Abstract It is established that coronaviruses are transmitted most through aerosols produced when an infected individual coughs or sneezes. Although there is no clear evidence of person-to-person airborne transmission, it is..

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Preoperative Endothelial Dysfunction in Cutaneous Microcirculation Is Associated with Postoperative Organ Injury After Cardiac Surgery Using Extracorporeal Circulation: A Prospective…

Abstract Background Cardiac surgery is known to induce acute endothelial dysfunction, which may be central to the pathophysiology of postoperative complications. Preoperative endothelial dysfunction could also be implicated in the..

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Perioperative Outcomes of Coronary Artery Bypass Graft Surgery in Johannesburg, South Africa

Abstract Background The perioperative complications in patients with coronary artery disease undergoing coronary artery bypass graft (CABG) surgery have been reported predominantly from developed countries, with a paucity of data..

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Universal Definition of Perioperative Bleeding in Cardiac Surgery Adults and Association with Mortality in A Mexican Cardiovascular Critical Care Unit

Abstract Background Bleeding as a complication is associated with poorer results in cardiac surgery. There is increasing evidence that the use of blood products is an independent factor of increased..

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Increased Cerebral Mitochondrial Dysfunction and Reactive Oxygen Species with Cardiopulmonary Bypass

Abstract Objectives Neurodevelopmental injury after cardiac surgery using cardiopulmonary bypass (CPB) for congenital heart defects is common, but the mechanism behind this injury is unclear. This study examines the impact..

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Anemia in Cardiac Surgery – Can Something Bad Get Worse?

Abstract Introduction Anemia and blood transfusion are risk factors for morbidity/mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The objective of this study is to analyze the association..

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Impact of Malnutrition on Survival in Adult Patients After Elective Cardiac Surgery: Long-Term Follow Up Data

The data article refers to the paper titles “Impact of malnutrition on long-term survival in adult patients after elective cardiac surgery” . The data refer to the analysis of the relationship..

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Tranexamic Acid and Convulsive Seizures After Isolated Coronary Artery Bypass Surgery: The Role of Cardiopulmonary Bypass and Renal Function

Abstract In cardiac surgical patients, tranexamic acid (TXA) has been associated with an increased risk of convulsive seizure (CS). We aimed to investigate whether in patients undergoing isolated coronary artery..

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Effects of Remote Ischemic Preconditioning on Platelet Activation and Reactivity in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass: A Randomized…

Abstract During cardiopulmonary bypass (CPB), platelet activation and dysfunction are associated with adverse outcomes. Remote ischemic preconditioning (RIPC) has been shown to attenuate platelet activation. We evaluated the effects of..

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Efficacy and Safety of Corticosteroids Prophylaxis in Cardiac Surgery: A Protocol for Systematic Review and Meta-Analysis

Background Although corticosteroid prophylaxis in adult cardiac surgery has been studied extensively for 40 years, its role remains controversial, and the optimal dose remains uncertain. The objective of this meta-analysis..

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High Versus Low Blood Pressure Targets for Cardiac Surgery with Cardiopulmonary Bypass

Abstract This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of a higher versus lower blood pressure target during..

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Investigation of Myocardial Protection During Pediatric CPB: Practical Experience in 100 Chinese Hospitals

Abstract Many measures have been proposed for myocardial protection in pediatric congenital heart surgeries, but little data is available for China. This study investigates myocardial protection strategies in pediatric cardiopulmonary..

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Managing Massive Transfusion Protocol During Cardiopulmonary Bypass in the Setting of Penetrating Traumatic Injury

Abstract A 34-year-old African American man was brought to the trauma resuscitation area with 2 gunshot wounds to his right anterior chest below his clavicle and his left back. On..

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In Vitro Evaluation of Flow Distribution in All-Region Perfusion during the Norwood Operation

Abstract Continuous all-region perfusion has the potential to reduce total body ischemia during the Norwood procedure. This technique involves placing cannulas in the innominate artery, descending aorta, and native aortic..

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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury

Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..

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Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time

Abstract Objective To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those..

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Cardiopulmonary Bypass Duration and the Incidence of Pressure Injuries in Patients Undergoing Cardiovascular Surgery

A Retrospective Cohort Study Purpose The purpose of our study was to investigate the association between cardiopulmonary bypass (CPB) duration and the incidence of pressure injuries (PIs) in patients undergoing..

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Impact of Permissive Hypercapnia on Regional Cerebral Oxygen Saturation and Postoperative Cognitive Function in Patients Undergoing Cardiac Valve Replacement

Abstract Background Cardiac valve replacement (CVR) is currently the main surgical treatment for patients with valvular heart diseases (VHD). Postoperative cognitive dysfunction (POCD) is one of the most serious complications..

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Goal-Directed Perfusion to Reduce Acute Kidney Injury after Paediatric Cardiac Surgery (GDP-Akip): Study Protocol for A Prospective Randomised Controlled Trial

Abstract Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~60% of paediatric patients and increases postoperative morbidity and mortality. A goal-directed perfusion (GDP) strategy aimed at maintaining..

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