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Perfusfind S.L.

Abstract Bleeding in the perioperative period of congenital heart surgery with cardiopulmonary bypass is associated with increased morbidity and mortality both from the direct effects of haemorrhage as well as..

Perfusfind S.L.

Abstract We retrospectively compared anticoagulation with heparin and bivalirudin for 32 consecutive children under 18 years old during extracorporeal membrane oxygenation (ECMO) in our pediatric cardiac intensive care unit (PCICU). Between September..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is a therapy used in severe cardiopulmonary failure. Blood is pumped through an artificial circuit exposing it to nonphysiologic conditions, which promote platelet activation and..

Perfusfind S.L.

Abstract Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available. However, up to now..

Perfusfind S.L.

Abstract The outbreak of the novel coronavirus pandemic (COVID-19) has resulted in dramatic changes to the conduct of surgery both from a patient management perspective and in protecting healthcare providers...

Perfusfind S.L.

Abstract Coagulation factor XII (fXII) is a plasma serine protease which belongs to the contact activation complex responsible for initiating the intrinsic coagulation pathway. fXII deficiency is a rare congenital..

Perfusfind S.L.

Abstract Clotting, anticoagulation, platelet consumption, and poor platelet function are major factors in clinical extracorporeal circulation (ECC). We have shown that nitric oxide-releasing (NOReL) coatings prevent thrombosis in a rabbit..

Perfusfind S.L.

Abstract Major surgery induces hemostatic changes related to surgical stress, tissue destruction, and inflammatory reactions. These changes involve a shift of volume from extravascular space to intravascular and interstitial spaces,..

Perfusfind S.L.

Lambl's excrescences are usually described as filiform (threadlike) fronds.  They were first described by Vilem Dusan Lambl, a Bohemian physician. They occur, by definition, along valve closure lines, where minor..

Perfusfind S.L.

Abstract Background Diagnosis of heparin-induced thrombocytopenia (HIT) requires pre-test probability assessment and dedicated laboratory assays. Objective To develop a pre-test score for HIT. Design Observational; analysis of prospectively collected data..

Perfusfind S.L.

Abstract Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease severity during hospitalization but the reported survival benefits from anticoagulation (AC) vary among studies. We performed a literature research to..

Perfusfind S.L.

Abstract Rheumatic heart disease (RHD) remains a neglected disease of poverty. While nearly eradicated in high‐income countries due to timely detection and treatment of acute rheumatic fever, RHD remains highly..

Perfusfind S.L.

Abstract Extracorporeal circuits including renal replacement therapy, extracorporeal membrane oxygenation, and ventricular assist devices are increasingly used in critically ill patients. The need for anticoagulation to provide circuit patency and..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) represents an established technique to provide temporary cardiac and/or pulmonary support. ECMO, in veno-venous, veno-arterial or in extracorporeal carbon dioxide removal modality, is associated with..

Perfusfind S.L.

Abstract The aim of this article is to provide a comprehensive review of the current state of knowledge on heparin-induced thrombocytopenia (HIT) in cardiac surgery. The management of HIT patients..

Perfusfind S.L.

Abstract THE USE of cardiopulmonary bypass has enabled the delivery of complex cardiovascular surgical procedures. Cardiopulmonary bypass (CPB), at its best, involves a highly technical process that is executed carefully..

Perfusfind S.L.

Abstract Antiphospholipid syndrome (APS) is an acquired autoimmune condition characterized by the presence of antiphospholipid antibodies (lupus anticoagulant, anticardiolipin antibody, and anti-β2 glycoprotein-I antibody) which leads to clinical thrombosis via a..

Perfusfind S.L.

Abstract Background To compare the safety and efficacy of low-dose anticoagulation (LA) with that of standardized dose anticoagulation (SA) for patients supported with extracorporeal membrane oxygenation (ECMO). Methods PubMed, MEDLINE,..

Perfusfind S.L.

Abstract Background: Acute type A aortic dissection (ATAAD) has a high risk of perioperative bleeding and often requires extensive blood product infusions. Analysis of the changes in coagulation and fibrinolysis..

Perfusfind S.L.

Abstract We present a case of acute myocarditis with left ventricular dysfunction and intracavitary thrombosis in a 55-year-old man with severe acute respiratory syndrome coronavirus 2 infection (coronavirus disease 2019)..

Perfusfind S.L.

Abstract Importance  Approximately 15% of patients undergoing cardiac surgery receive frozen plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have logistical and safety advantages over FP and may be a..

Perfusfind S.L.

Abstract Background: Thromboembolism and bleeding contribute to Coronavirus disease 2019 (COVID-19)’s morbidity and mortality and are also frequent complications of venovenous extracorporeal membrane oxygenation (vvECMO). As the interaction of the..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) bridge to lung transplantation (LuTX) exposes the patients to a high risk of perioperative bleeding secondary to systemic anticoagulation and coagulation factors deficiency. With this..

Perfusfind S.L.

Abstract Objective Failure of membrane oxygenator (MO) function of venovenous extracorporeal membrane oxygenators (VV ECMO) remains problematic. The development of device-induced coagulation disorder (COD) or worsened gas transfer (WGT) necessitates..

Perfusfind S.L.

Abstract Background Hemorrhagic events remain a major concern in patients under extracorporeal membrane oxygenation (ECMO) support. We tested the association between anticoagulation levels and hemorrhagic events under ECMO using anti-Xa..

Perfusfind S.L.

The learner will be able to discuss anticoagulation strategies for patients on ECMO.   

Perfusfind S.L.

ECMO: Measurement Of Adequacy, Cannulation, North/South Complication, Anticoagulation And Weaning, And What Patients Can Be Woken Up And Extubated On VV ECMO?   

Perfusfind S.L.

Joe presents data on the commonality of clot burden in the ECMO circuit and how difficult it is to detect without a tool that can directly measure intra-oxygenator volume in..

Perfusfind S.L.

Joe Basha, CCP and John Ingram, CCP talk about anticoagulation strategies for ECMO patients.  Joe and John discuss SCCM guidelines and their own experiences with different anticoagulation protocols.   

Perfusfind S.L.

Joe Basha, CCP and John Ingram, CCP talk about anticoagulation strategies for ECMO patients.  Joe and John discuss SCCM guidelines and their own experiences with different anticoagulation protocols.