Archives

Perfusfind S.L.

Abstract Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or..

Perfusfind S.L.

Abstract Background Prior studies have implicated transfusion as a risk factor for mortality in coronary artery bypass graft surgery (CABG). To further our understanding of the true association between transfusion..

Perfusfind S.L.

Abstract Background Severe post‐operative bleeding in cardiac surgery is associated with increased morbidity and mortality. We hypothesized that variation in genetic susceptibility contributes to post‐operative bleeding in addition to clinical..

Perfusfind S.L.

Abstract Summary To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity..

Perfusfind S.L.

Abstract Background  support (ECMO) typically requires multiple  and is associated with frequent bleeding complications. Blood transfusions are known to increase morbidity and mortality in critically ill patients, which may extend to..

Perfusfind S.L.

Abstract Thrombocytopenia and platelet dysfunction induced by extracorporeal blood circulation are thought to contribute to postsurgical bleeding complications in neonates undergoing cardiac surgery with cardiopulmonary bypass (CPB). In this study,..

Perfusfind S.L.

Abstract Objectives During cardiac surgery, circulating red blood cells (RBCs) are at risk of exposure to environmental factors during  and transfusion of stored RBCs. For this study, the authors observed morphological..

Perfusfind S.L.

Abstract Background Levosimendan, a calcium sensitizer and potassium channel opener, has been demonstrated to improve myocardial function without increasing oxygen consumption and to show protective effects in other organs. Recently,..

Perfusfind S.L.

Abstract Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical patients in association with patient (advanced age,..

Perfusfind S.L.

Abstract Summary Few studies have investigated if, and how, red cell transfusion and anaemia interact. We analysed 60,955 admissions to three metropolitan hospitals in Western Australia between 2008 and 2017..

Perfusfind S.L.

Abstract OBJECTIVES: The upcoming release of aprotinin in paediatric cardiac surgery prompted a re-evaluation of its use in comparison to tranexamic acid (TXA) focusing on their effect on exposure to..

Perfusfind S.L.

Abstract OBJECTIVES Between 2% and 8% of patients return to the theatre for mediastinal bleeding following cardiac surgery. In the majority of patients, a surgical source of bleeding is identified...

Perfusfind S.L.

Abstract Objectives Prolonged  (CPB) is recognized as a risk factor for  (ARF), but the dose effect of time on bypass is unknown. We therefore examined the risk of ARF associated with increasing..

Perfusfind S.L.

Abstract Summary We investigated microcirculatory perfusion disturbances following cardiopulmonary bypass in the early postoperative period and whether the course of these disturbances mirrored restoration of endothelial glycocalyx integrity. We performed..

Perfusfind S.L.

Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of  have been associated with increased morbidity in pediatric cardiac patients. Transfusion..

Perfusfind S.L.

Abstract Background Venoarterial (VA)  (ECMO) application in postcardiotomy shock (PCS) and non-PCS is increasing. VA-ECMO plays a critical role in the management of these patients, yet may be associated with serious..

Perfusfind S.L.

Abstract We currently perform open-heart procedures using bloodless priming of cardiopulmonary bypass circuits regardless of a patient’s body weight. This study presents results of this blood-saving approach in neonates and..

Perfusfind S.L.

Objective To determine the relationships between hypothermia and pH at surgery end and postoperative red blood cell (RBC) transfusion in massively transfused adult cardiac surgery patients. Design . Setting Single..

Perfusfind S.L.

Abstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..

Perfusfind S.L.

Abstract Measurement of lactate concentrations during cardiac surgery with cardiopulmonary bypass (CPB) is a reliable monitoring tool for the assessment of the adequacy of perfusion, and a predictor of poor..

Perfusfind S.L.

Abstract Background: Ultrafiltration during cardiopulmonary bypass (CPB) reduces fluid overload and inflammatory mediators in open-heart surgery and is thought to reduce the risk of red blood cell (RBC) transfusion. We..

Perfusfind S.L.

Abstract Purpose To examine the effect of discontinuing hydroxyethyl starch (HES) solutions on length of hospital stay, transfusion, risk of death, acute kidney injury (AKI), and dialysis. Methods We conducted..

Perfusfind S.L.

Abstract Blood priming is needed for cardiopulmonary bypass (CPB) in neonates and infants to avoid exceeding hemodilution; however, transfusion‐related inflammation affects post‐CPB outcomes in infant open‐heart surgery. Procalcitonin, a newly..

Perfusfind S.L.

Abstract Introduction:  Increasing the hematocrit is considered to increase oxygen delivery to the patient, especially when hypoxic conditions exist and the patient may become more stable. The aim of this..

Perfusfind S.L.

Abstract BACKGROUND: Although bloodless cardiac surgery has been successfully performed for many years, studies with controls permitting transfusion are few and their results inconclusive. This study compares the outcome of..

Perfusfind S.L.

Abstract Efforts to reduce blood product transfusions and adopt blood conservation strategies for infants and children undergoing cardiac surgical procedures are ongoing. Children typically receive red blood cell and coagulant..

Perfusfind S.L.

Abstract Objectives The aim of the study was to investigate whether the HeProCalc algorithm affects heparin and  dosage, , and transfusion rate. Design Randomized controlled trial. Setting University hospital. Participants The..

Perfusfind S.L.

Abstract Background To determine national benchmarks and assess variability across centers, The Society of Thoracic Surgeons Congenital Heart Surgery Database was analyzed to document proportions of patients receiving intraoperative transfusion..

Perfusfind S.L.

Abstract Introduction: Tracheostomy has been utilized in combination with venovenous extracorporeal membrane oxygenation (VV-ECMO) to enable early spontaneous breathing and minimize sedation requirements. Tracheostomy has been previously reported to be..

Perfusfind S.L.

Abstract Background Over the past decade, minimally invasive mitral valve surgery (MIMVS) has grown in popularity. Less invasive approaches to mitral valve surgery are increasingly used for improved cosmesis. We..