Archives

thumbnail
0 comment

Early versus delayed post-transfusion hemoglobin and hematocrit measurement in adults: a narrative review

Abstract Delaying the measurement of a complete blood count (CBC) for 6 to 24 hours after red blood cell transfusion remains a common practice in hospitals worldwide, despite the absence..

Read More
thumbnail
0 comment

Machine learning-based prediction of significant intraoperative blood loss to guide risk-adapted blood management decisions in spinal surgery

Abstract Introduction Significant blood loss (≥ 500 mL) during spinal surgery is common and linked to greater transfusion requirements and worse outcomes. Preoperative tools for risk stratification and individualized blood-management strategies..

Read More
thumbnail
0 comment

Smart Clot: An Automated Point-of-Care Flow Assay for Quantitative Whole-Blood Platelet, Fibrin, and Thrombus Kinetics

Abstract Hemostasis depends on the coordinated interaction between platelets, coagulation factors, endothelium, and shear forces. Current point-of-care (POC) assays evaluate isolated components of haemostasis or operate under nearly static conditions,..

Read More
thumbnail
0 comment

How does rewarming temperature affect bleeding after mitral valve repair?

Abstract Objective So far, evidence is scarce regarding the impact of rewarming temperature on bleeding after cardiac surgery under cardiopulmonary bypass (CPB). We seek to evaluate how rewarming temperature affects..

Read More
thumbnail
0 comment

Adjuvant Autologous Platelet-Rich Plasma Gel for Decreasing Blood Loss in Posterior Placenta Previa: A Case Series and Literature Review

Abstract We reported two cases of posterior placenta previa managed with elective cesarean delivery and adjunctive autologous platelet-rich plasma (PRP) gel. Twelve milliliters of PRP gel were used to cover..

Read More
thumbnail
0 comment

Prevention of blood dilution during cardiopulmonary bypass surgery in a cat with ventricular septal defect

Abstract A six-month-old, 3.3-kg, intact male American shorthair cat with a ventricular septal defect (VSD) underwent open-heart surgery using total cardiopulmonary bypass. Repair of the VSD was performed via a..

Read More
thumbnail
0 comment

The role of mediastinal blood in the development of postoperative atrial fibrillation after cardiac surgery

Abstract Introduction Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery. Although many risk factors have been studied, none has emerged as a dominant and widely applicable prophylactic measure. Aim..

Read More
thumbnail
0 comment

Predictors and Economic Impact of Red Blood Cell Transfusion in Cardiac Surgery: A Simulated Cost Reduction Model for Preoperative Anemia…

Abstract Introduction: Red blood cell (RBC) transfusions are frequent in cardiac surgery and are associated with higher morbidity, mortality, prolonged hospitalization, and increased healthcare costs. Several patient- and procedure-related factors have..

Read More
thumbnail
0 comment

Perioperative Transfusion Requirements in Pediatric Patients Receiving Apixaban Prior to Cardiac Surgery With Cardiopulmonary Bypass

Abstract Design Apixaban is a direct oral anticoagulant that inhibits factor Xa. Our objective was to examine the effect of apixaban on perioperative transfusion requirements in pediatric patients undergoing cardiac..

Read More
thumbnail
0 comment

The case against infusing ABO incompatible antibody and antigen from all blood components

Abstract The transfusion of ABO compatible but not ABO identical red blood cells and plasma and the transfusion of platelets and cryoprecipitate without concern for ABO in any manner, are..

Read More
thumbnail
0 comment

Predicting intraoperative transfusion volumes of blood products in cardiovascular surgery: a retrospective study

Abstract Background and Objectives Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a..

Read More
thumbnail
0 comment

Restoring the Morphology and Function of Damaged Red Blood Cells

Abstract Red blood cells (RBCs) play a crucial role in delivering oxygen to tissues with their distinctive shape. However, the mechanisms underlying cellular deformation and rupture due to stress, which..

Read More
thumbnail
0 comment

ECMO decannulation is associated with dynamic changes in coagulation profiles: an exploratory, nested cohort study

Abstract Background ECMO-associated coagulopathy is a common phenomenon in patients undergoing ECMO therapy. However, data on coagulation trajectories in the post ECMO decannulation period are limited. This study aimed to..

Read More
thumbnail
0 comment

Marginal Band Collapsing: Structural Insights Into Shear-Induced Platelet Activation Relevant to Circulatory Assist Devices

Abstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..

Read More
thumbnail
0 comment

Bleeding in Patients With Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy

Abstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..

Read More
thumbnail
0 comment

Twenty-eight cases of thalassemia: A retrospective study of autologous and allogeneic erythrocyte transfusions during cesarean section

Abstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..

Read More
thumbnail
0 comment

Autotransfusion in traumatic haemothorax using the Sinapi chest drain system

Abstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..

Read More
thumbnail
0 comment

Blood Conservation Protocol for Patients Undergoing Left Ventricular Assisted Device Implantation

Abstract Objectives:  This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..

Read More
thumbnail
0 comment

Clinical Evaluation of the Hemostatic Efficacy and Safety of a Biodegradable Hemostatic Agent, Hemogram: A Comparative Study with Arista™ AH

Abstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..

Read More
thumbnail
0 comment

Development and validation of a machine learning-based prediction model for thrombocytopenia following cardiopulmonary bypass

Abstract Postoperative thrombocytopenia (TP) is a serious complication of cardiopulmonary bypass (CPB). An accurate prediction model is crucial for the early identification of high-risk patients. This study aimed to develop..

Read More
thumbnail
0 comment

Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), an emerging resuscitative therapy following refractory cardiac arrests, is associated with hemorrhagic complications that potentially affect patient outcomes. Objectives This study evaluated the risks..

Read More
thumbnail
0 comment

Cell salvage in bacterially contaminated surgical fields – A scoping review

Abstract Objective This scoping review systematically examines the use of intraoperative cell salvage in bacterially contaminated surgical settings, examining contamination levels, decontamination strategies, and clinical outcomes following the reinfusion of..

Read More
thumbnail
0 comment

Anaemia and blood transfusion in cardiac surgery with infective endocarditis

Abstract Background Up to half of patients with infective endocarditis (IE) require cardiac surgery. Although anaemia is common, its precise prevalence, transfusion practices and impact on outcomes in surgically treated IE..

Read More
thumbnail
0 comment

Extracorporeal Blood Purification with CytoSorb in Patients with Shock: A Secondary Analysis of Standalone Circuit Configuration Versus Integrated Use within…

Abstract Objectives CytoSorb, an extracorporeal blood purification device composed of biocompatible, highly porous polymer beads, is being increasingly adopted in different critically ill settings to allow for both enhanced organ..

Read More
thumbnail
0 comment

Postoperative Thrombocytopenia in Cardiac Surgery: Patterns, Differential Diagnosis and Management of Heparin-Induced Thrombocytopenia (HIT)

Abstract Background: Postoperative thrombocytopenia is a frequent finding after cardiac surgery, affecting approximately 10–40% of patients. The early decline in platelet count, typically observed within the first 48–72 h, is..

Read More
thumbnail
0 comment

Efficacy and Feasibility of Preoperative Autologous Blood Donation in Elective On-pump Cardiac Surgeries: A Propensity-score Matching Study

Abstract Objective: The global shortage of blood resources has become a significant concern. This study aimed to assess the effects and feasibility of preoperative autologous blood donation (PABD) in elective..

Read More
thumbnail
0 comment

What is the ideal solution for washing salvaged red blood cells using a cell saver for autotransfusion during surgery

Abstract There are three reasons why perfusionists and autotransfusionists around the globe still use Normal Saline with cell savers; (1) This what they were taught by their peers and/or didactic..

Read More
thumbnail
0 comment

Cold-stored platelets: A systematic review of recovery in healthy adults and chest drain output in cardiothoracic surgery patients

Abstract Cold-stored platelets were abandoned in the 1960s after demonstration of an increased clearance in vivo due to an irreversible activated phenotype. Difficulties in storage, logistics, and the increased requirement..

Read More
thumbnail
0 comment

Effects of intraoperative cell salvage versus preoperative autologous blood donation on postoperative coagulation in cardiac surgery

Abstract  Objective: To compare the effects of intraoperative cell salvage (ICS) and preoperative autologous blood donation (PABD) on postoperative coagulation and platelet function in patients undergoing cardiac surgery, and to..

Read More
thumbnail
0 comment

Cost-Effectiveness of Cryopreserved vs Liquid-Stored Platelets for Managing Surgical Bleeding

Abstract Importance  Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..

Read More