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Cardiopulmonary bypass parameters improve the prediction of 30-day mortality following cardiac surgery

Abstract Currently 30-day mortality is commonly used as a quality indicator for cardiac surgery; however, prediction models have not included the role of cardiopulmonary bypass (CPB). We hypothesized that reproducing..

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High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass

Abstract Background Cardiac surgery is performed worldwide. Most types of cardiac surgery are performed using cardiopulmonary bypass (CPB). Cardiac surgery performed with CPB is associated with morbidities. CPB needs an..

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Intraoperative cell salvaging: ex vivo evaluation of two swab-washing methods

Abstract OBJECTIVE To compare erythrocyte recovery by a cell salvage device between swab-washing by manual agitation or filtration. SAMPLE 12 recently expired units of canine packed RBCs. PROCEDURE The packed..

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The Use of Autotransfusion in Trauma Surgery

Abstract Autotransfusion, also known as autologous transfusion, is a technique that involves collecting a patient's own blood before or during surgery and then transfusing it back into the patient. This..

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A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery

Abstract The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a “patient-focused, evidence-based and systematic approach for optimizing the..

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Short and long-term outcomes after cardiac surgery in Jehovah’s Witnesses patients: a case–control study

Abstract Cardiac surgery in Jehovah’s Witnesses (JW) patients who refuse blood transfusion is challenging requiring dedicated strategies. We aimed to analyze non-selected JW patients undergoing cardiac surgery and to compare..

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Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding

Abstract Background Coagulopathy following cardiac surgery is associated with considerable blood product transfusion and high morbidity and mortality. The treatment of coagulopathy following cardiac surgery is challenging, with the replacement of..

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Cell Salvage at the ICU

Abstract Patient Blood Management (PBM) is a patient-centered, systemic and evidence-based approach. Its target is to manage and to preserve the patient’s own blood. The aim of PBM is to..

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Intraoperative blood collection without fluid replacement for cardiac surgery – A retrospective analysis

Abstract Background: Transfusion rates in cardiac surgery are high. Aim: To determine if intraoperative autologous blood removal without volume replacement is associated with fewer homologous blood transfusions without increasing acute kidney injury...

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Creating blood conservation for a cardiothoracic surgical hospital: when you have to start from scratch

Abstract Background: This improvement report presents a hospital blood-management programme, a hospital-specific model that differs from patient blood managment and was aimed at improving operational standards of transfusion. We identified..

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Acute Kidney Injury With a Miniaturized Extracorporeal Circuit for Neonatal Cardiopulmonary Bypass

Abstract Objectives The objectives of this study were to evaluate the incidence and to identify risk factors for acute kidney injury (AKI) in neonates undergoing cardiopulmonary bypass (CPB) with a..

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The Choice of Protamine Sulfate Dosing Regimen for Coronary Artery Bypass Graft Surgery

Abstract Changes in hemodynamics and coagulation hemostasis during the use of protamine sulfate to neutralize heparin in a ratio of 0.5:1 in coronary artery bypass graft surgery have been studied...

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A prospective randomized study comparing volume-standardized modified and conventional ultrafiltration in pediatric cardiac surgery

Abstract Background: Modified ultrafiltration has been touted as superior to conventional ultrafiltration for attenuating the consequences of hemodilution after cardiac surgery with cardiopulmonary bypass in children. We conducted a prospective randomized..

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Acute kidney injury following cardiopulmonary bypass in Jamaica

Abstract Objectives The study objectives were to describe the incidence, risk factors, and outcomes of acute kidney injury after cardiopulmonary bypass in Jamaica. Method We performed a review of the..

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Platelet preservation in cardiac surgery using minimally invasive extracorporeal circulation versus optimized cardiopulmonary bypass

Abstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..

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Vasoplegia is Predicted by Preoperative Platelet-Leucocyte conglomerate Indices in Cardiac Surgery (VASOPLEGICS): A retrospective single-center study

Abstract Background: Post-cardiotomy vasoplegia syndrome (VS) is often linked to an exaggerated inflammatory response to cardiopulmonary bypass (CPB). At the same time, the prognostic role of platelet-leucocyte indices (PLIs) and leucocyte..

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Simple open-heart surgery protocol for sickle-cell disease patients: a retrospective cohort study comparing patients undergoing mitral valve surgery

Abstract OBJECTIVES Sickle-cell disease (SCD) patients are considered to be at high risk from open-heart surgery. This study assessed the role of a simple sickling-prevention protocol. METHODS Perioperative non-specific and..

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Risk Factors and Consequences of Late-Onset Hyperlactatemia After Cardiac Surgery With Cardiopulmonary Bypass: A Single-Center Retrospective Study

Abstract Objective Mechanisms and consequences of late-onset  after cardiac surgery remain unclear. The aim of this study was to identify risk factors and outcomes of late , defined as a lactate value..

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Hemolysis in patients with Extracorporeal Membrane Oxygenation therapy for severe Acute Respiratory Distress Syndrome - a systematic review of the…

Abstract The Acute Respiratory Distress Syndrome (ARDS) is common in patients on the Intensive Care Unit and associated with significant mortality rates. In situations of severe respiratory insufficiency and failure..

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Platelet preservation in cardiac surgery using minimally invasive extracorporeal circulation versus optimized cardiopulmonary bypass

Abstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..

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The prognostic significance of postoperative hyperbilirubinemia in cardiac surgery: systematic review and meta-analysis

Abstract Background Hyperbilirubinemia following cardiac surgery is a common phenomenon and is of emerging interest in prognostic factor research. This systematic review and meta-analysis evaluated the association between post-operative hyperbilirubinemia..

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Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency…

Abstract Preoperative anemia is common in patients presenting for cardiac surgery, with a prevalence of approximately 1 in 4, and has been associated with worse outcomes including increased risk of..

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Critical Preoperative Hemoglobin Value to Predict Anemia-Related Complications After Cardiac Surgery

Abstract Objectives Preoperative anemia is frequent in patients undergoing cardiac surgery and is associated with increased postoperative complications.  Design A retrospective observational cohort study. Setting A tertiary-care medical center from..

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Impact of gender differences on hemostasis in patients after coronary artery bypass grafts surgeries in the context of tranexamic acid…

Abstract Background Sex differences present in the blood management of patients after coronary artery bypass grafts (CABG) surgeries. Tranexamic acid (TXA) performed well in maintaining hemostasis during and after surgeries...

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Outcome of type and screen versus crossmatch in cardiovascular surgery patients: A comparative study

Abstract BACKGROUND: The need for an anti-human globulin (AHG) cross-match (XM) when the antibody screen (ABS) is negative is debatable and a matter of policy. AIM: (1) To compare the outcomes of..

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Effects of crystalloid and colloid priming strategies for cardiopulmonary bypass on colloid oncotic pressure and haemostasis: a meta-analysis

Abstract   OBJECTIVES Colloid oncotic pressure (COP) is an important factor in cardiac surgery, owing to its role in haemodilution. The effect of cardiopulmonary bypass prime fluids on the COP..

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Titrated versus conventional anticoagulation management for thrombin generation in cardiac surgery: a randomized controlled trial

Abstract Purpose Optimal heparin titration during cardiopulmonary bypass (CPB) may reduce coagulation system activation and preserve hemostatic function post-CPB. Our objective was to assess if the Heparin Management System (HMS)..

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Management of perioperative bleeding risk in patients on antithrombotic medications undergoing cardiac surgery—a systematic review

Abstract Background: Antithrombotic drugs increase the risk of bleeding, especially in patients who need urgent surgery without an adequate wash-out period. This review aims to evaluate perioperative bleeding complications in..

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Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a post hoc analysis…

Abstract Background Coagulopathy in cardiac surgery is frequently associated with acquired hypofibrinogenaemia, which can be treated with either purified fibrinogen concentrate (FC) or cryoprecipitate. Because the latter is not purified..

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Cannulas and Cannulation Options for Minimally Invasive Surgery

Abstract Traditionally, cardiac surgery has been practiced primarily through a median sternotomy; however, as instrumentation and experience continue to advance at exponential rates, the field of minimally invasive cardiac surgery..

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