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Safety of bloodless open-heart surgery on cardiopulmonary bypass in selected children: A single center experience with minimal invasive extracorporeal circulation

Abstract Introduction Bloodless cardiac surgery refers to open-heart surgery without blood or blood products. The cardiopulmonary bypass (CPB) circuits are primed with crystalloid solely, and there is no intraoperative blood..

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Comparison of anticoagulation monitoring strategies for adults supported on extracorporeal membrane oxygenation: A systematic review

Abstract Background Anticoagulation is critical in patients supported on extracorporeal membrane oxygenation (ECMO). The appropriate monitoring strategies for heparin remain unclear. Objectives This systematic review aimed to compare the accuracy..

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Coagulation support during perioperative bleeding management

Abstract Bleeding is a leading cause of perioperative mortality []. In a perioperative setting, damage control surgery with massive transfusion protocols (MTPs) are therapeutic approaches used clinically to manage patients..

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Intraoperative use of cell saver devices decreases the rate of hyperlactatemia in patients undergoing cardiac surgery

Abstract Objective This study was aimed to elucidate the effect of the intraoperative cell saver (CS) on hyperlactatemia of patients who underwent cardiac surgery. Design A sub-analysis of the CS..

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Association of Conventional Ultrafiltration on Postoperative Pulmonary Complications

Abstract Background Postoperative pulmonary complications increase mortality after cardiac surgery. Conventional ultrafiltration may reduce pulmonary complications by removing mediators of bypass-induced inflammation and countering hemodilution. We tested the primary hypothesis..

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Perioperative Trajectory of Haemoglobin, Predictors of Blood Transfusion and Tailoring Targets for Patient Blood Management Interventions: A Single-centre, Retrospective Study…

Abstract Background Anaemia and blood transfusion are two independent contributing factors to perioperative morbidity in cardiac surgery. While preoperative treatment of anaemia has been shown to improve outcomes, in real..

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Effects of Patient Sex on Neurocognitive Decline after Cardiac Surgery

Abstract Background:  Neurocognitive decline (NCD) is a common complication of cardiac surgery. Understanding risk factors helps surgeons counsel patients pre- and peri-operatively about risk, prevention, and treatment. Results:  Eighty-four patients undergoing cardiac surgery utilizing..

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Refraining from Packed Red Blood Cells in Cardiopulmonary Bypass Priming as a Method of Neuroprotection in Pediatric Cardiac Surgery

Abstract Congenital heart defect (CHD) surgeries are performed with cardiopulmonary bypass (CPB) and are complicated by several factors that affect the child’s brain. However, to date, the number of studies..

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Coagulation Tests and Bleeding Classification After Cardiopulmonary Bypass: A Prospective Study

Abstract Objective No recent prospective studies have analyzed the accuracy of standard coagulation tests and thromboelastography (TEG) to identify patients with excessive microvascular bleeding following cardiopulmonary bypass (CPB). The aim..

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Are Viscoelastic Tests Clinically Useful to Identify Platelet-Dependent Bleeding in High-Risk Cardiac Surgery Patients?

Abstract BACKGROUND:  Postoperative use of platelet function testing to rule out microvascular bleeding due to platelet dysfunction after cardiac surgery still lacks strong reference data and reliable cutoff values, yielding..

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A comparison of the ClotPro system with rotational thromboelastometry in cardiac surgery: a prospective observational study

Abstract Viscoelastic coagulation tests have been increasingly used for hemostasis management in cardiac surgery. The ClotPro system is a novel viscoelastic device based on principles of rotational thromboelastometry. We aimed..

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Effects of rapid fluid infusion on hemoglobin concentration: a systematic review and meta-analysis

Abstract Background Rapid fluid administration may decrease hemoglobin concentration (Hb) by a diluting effect, which could limit the increase in oxygen delivery (DO2) expected with a positive response to fluid..

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Intraoperative cell salvage using swab wash and serial thromboelastography in elective abdominal aortic aneurysm surgery involving massive blood loss

Abstract The loss of 50% blood volume is one accepted definition of massive haemorrhage, which ordinarily would trigger the massive transfusion protocol, involving the administration of high ratios of fresh..

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A Surgeon's Perspective on Blood Conservation Practice in Pediatric Cardiac Surgery

Abstract Blood conservation practice in pediatric cardiac surgery has not been consistently adopted as quality improvement in many centers despite known risks associated with allogeneic blood products, shortage of donors,..

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Patient blood management and patient safety

Abstract Purpose of review  The particular fields within patient blood management (PBM) and patient safety reviewed here include novel insights into bleeding therapy, autologous cell salvage, and perioperative anemia therapy. Recent finding  World Health Organization..

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Albumin Use After Cardiac Surgery

Abstract Objectives: To investigate the effect of albumin exposure in ICU after cardiac surgery on hospital mortality, complications, and costs. Design: A retrospective, single-center cohort study with economic evaluation. Setting:..

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New horizons for reduction of blood use: Patient blood management

Abstract A countrywide study over the eras indicates overuse of blood transfusion can have considerable risks to patients accompanied by significant costs of blood transfusion for patients, hospitals, and health-care..

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Haematic antegrade repriming to enhance recovery after cardiac surgery from the perfusionist side

Abstract Background: New era of cardiac surgery aims to provide an enhanced postoperative recovery through the implementation of every step of the process. Thus, perfusion strategy should adopt evidence-based measures..

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Relationship between perioperative cardiopulmonary bypass time, platelet count, fibrinogen level, rotational thromboelastometry data, antithrombin level, and blood loss volume and…

Abstract Introduction We hypothesized that perioperative fibrinogen level, platelet count, and rotational thromboelastometry (ROTEM) data values decrease in proportion to cardiopulmonary bypass (CPB) time, particularly in patients who underwent deep..

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Extracorporeal membrane oxygenation for critically ill adults

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a form of life support that targets the heart and lungs. Extracorporeal membrane oxygenation for severe respiratory failure accesses and returns blood from the..

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The pressure field as a methodology for fluid management and red cell preservation during cardiac surgery

Abstract Purpose Anemia and red cell transfusion contribute to morbidity and mortality of surgery. The concept of patient blood management to mitigate preoperative anemia, optimize coagulation, conserve red cells intraoperatively..

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PROTOCOLO NACIONAL DE TRASPLANTE CARDíACO INFANTIL AB0 INCOMPATIBLE

Abstract La práctica del trasplante AB0 incompatible (AB0i) surgió en el Hospital Sick Children de Toronto (Canadá) bajo el liderazgo de la Doctora Lori J. West, cardióloga e inmunóloga pediátrica..

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Causes of red blood cell loss during extracorporeal membrane oxygenation

Abstract Background Pediatric patients on extracorporeal membrane oxygenation (ECMO) often receive repeated red blood cell (RBC) transfusions. This study aims to quantify and characterize causes of RBC loss on ECMO...

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Perioperative Management of the Patient at High-Risk for Cardiac Surgery-Associated Acute Kidney Injury

Abstract Acute kidney injury (AKI) is one of the most common major complications of cardiac surgery, and is associated with increased morbidity and mortality. Cardiac surgery-associated AKI has a complex,..

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The multifactorial dynamic perfusion index: A predictive tool of cardiac surgery associated acute kidney injury

Abstract Introduction Cardiac surgery associated acute kidney injury (CSA-AKI) has a number of preoperative and intraoperative risk factors. Cardiopulmonary bypass (CPB) factors have not yet been elucidated in a single..

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Cardiopulmonary bypass parameters improve the prediction of 30-day mortality following cardiac surgery

Abstract Currently 30-day mortality is commonly used as a quality indicator for cardiac surgery; however, prediction models have not included the role of cardiopulmonary bypass (CPB). We hypothesized that reproducing..

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High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass

Abstract Background Cardiac surgery is performed worldwide. Most types of cardiac surgery are performed using cardiopulmonary bypass (CPB). Cardiac surgery performed with CPB is associated with morbidities. CPB needs an..

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Intraoperative cell salvaging: ex vivo evaluation of two swab-washing methods

Abstract OBJECTIVE To compare erythrocyte recovery by a cell salvage device between swab-washing by manual agitation or filtration. SAMPLE 12 recently expired units of canine packed RBCs. PROCEDURE The packed..

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The Use of Autotransfusion in Trauma Surgery

Abstract Autotransfusion, also known as autologous transfusion, is a technique that involves collecting a patient's own blood before or during surgery and then transfusing it back into the patient. This..

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A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery

Abstract The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a “patient-focused, evidence-based and systematic approach for optimizing the..

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