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Transfusion of red blood cells in venoarterial extracorporeal membrane oxygenation: A multicenter retrospective observational cohort study

Abstract Background Evidence-based recommendations for transfusion in patients with venoarterial extracorporeal membrane oxygenation (VA ECMO) are scarce. The current literature is limited to single-center studies with small sample sizes, therefore..

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Increasing obesity is associated with lower postoperative bleeding in coronary bypass patients

Abstract Objective Despite inherent comorbidities, obese cardiac surgical patients paradoxically had shown lower morbidity and mortality, although the nature of this association is still unclear. Thus, the authors intended in..

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Rotational Thromboelastometry–Guided Use of Synthetic Blood Products in Cardiac Transplant Patients: A Retrospective Before-After Study

Abstract Objectives Viscoelastic  assays, such as rotational  (ROTEM), are used increasingly in cardiac surgery to guide transfusion decisions. After separation from  (CPB), achieving  rapidly is the main goal before chest closure. The authors hypothesized..

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Impact of Transfused Citrate on Pathophysiology in Massive Transfusion

Abstract OBJECTIVES:  This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES:  A limited library of curated articles..

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ABO Blood Group and Bleeding and Survival in VA-ECMO Patients

Abstract ABO blood group has been shown to be a major determinant of plasma von Willebrand factor (vWF) levels. O blood group is associated with the lowest vWF levels and..

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Effect of lactate levels on extubation time in coronary artery bypass grafting surgery

Abstract Aim: In current practice, fast-track protocols are gaining importance in patients undergoing cardiac surgery. For this purpose, besides different application techniques, biomarkers are frequently examined in the peri-operative period...

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Circuit change during extracorporeal membrane oxygenation: single-center retrospective study of 48 changes

Abstract Background Bleeding and thrombosis induce major morbidity and mortality in patients under extracorporeal membrane oxygenator (ECMO). Circuit changes can be performed for oxygenation membrane thrombosis but are not recommended..

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Congenital cardiac surgery in a patient with cold agglutinins

Abstract Cold agglutinin disease is a type of autoimmune haemolytic anaemia caused by autoantibodies that bind to red blood cell antigens at a cold temperature and causes extravascular haemolysis and..

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The interaction of thrombocytopenia, hemorrhage, and platelet transfusion in venoarterial extracorporeal membrane oxygenation: a multicenter observational study

Abstract Background Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supportedwith venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to smallsingle‑center experiences with high degrees of..

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Con: Artificial Intelligence–Derived Algorithms to Guide Perioperative Blood Management Decision Making

Abstract Artificial intelligence has the potential to improve the care that is given to patients; however, the predictive models created are only as good as the base data used in..

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Which Vasopressors and Inotropes to Use in the Intensive Care Unit

Abstract Introduction Cardiac output (CO) is a key determinant of oxygen delivery. Low cardiac output syndrome (LCOS) causes organ dysfunction, prolonged hospital stay, and reduces survival in perioperative settings and..

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Planned improvement actions based on patient safety incident reports in Estonian hospitals: a document analysis

Abstract Aim Aim of this study was to describe and analyse associations of incidents and their improvement actions in hospital setting. Methods It was a retrospective document analysis of incident reporting systems’..

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Ambulation of Patients With In Situ Femoral Intraaortic Balloon Pump While Awaiting Heart Transplantation

Abstract With the implementation of the new allocation system in the United States on October 18, 2018, patients requiring temporary mechanical circulatory support (tMCS) have the highest priority, a shorter..

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THE USE OF AUTOLOGOUS BLOOD TRANSFUSION IN DIGESTIVE TRACT SURGERY: A LITERATURE REVIEW

Abstract Background: The use of autologous blood transfusion in digestive tract surgeries, whether after preoperative blood collection or intraoperative blood salvage, is an alternative to allogeneic blood, which brings with..

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Thromboelastographic evaluation after cardiac surgery optimizes transfusion requirements in the intensive care unit: a single-center retrospective cohort study using an…

Abstract Objective There are no reports from Japan showing the effects of using the thromboelastography algorithm on transfusion requirements after Intensive Care Unit (ICU) admission, and post-implementation knowledge regarding the..

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Current Evidence and Rationale to Guide Perioperative Management, Including Transfusion Decisions, in Patients With Sickle Cell Disease

Abstract Sickle cell disease (SCD) is a collection of inherited hemoglobin disorders that results in chronic hemolytic anemia, vaso-occlusion, pain, and end organ damage. Surgery in the SCD population requires..

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Blood protection of autologous platelet-rich plasma in long-time aortic root reconstruction: A retrospective study

Abstract Objective This study aimed to investigate the blood protective effect of autologous platelet-rich plasma in aortic root reconstruction under longtime cardiopulmonary bypass. Method Patients who underwent aortic root reconstruction..

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Cardiopulmonary bypass in neonates and infants: advantages of high flow high hematocrit bypass strategy—clinical practice review

Abstract Cardiopulmonary bypass is an integral and indispensable part of surgical repair of congenital heart defects. While the complications and morbidity secondary to the use of cardiopulmonary bypass has decreased..

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Point-of-Care Viscoelastic Hemostatic Assays in Cardiac Surgery Patients: Comparison of Thromboelastography 6S, Thromboelastometry Sigma, and Quantra

Abstract Objectives Viscoelastic tests allow a reduction in blood product transfusion. Three modern devices are currently available (rotational  [ROTEM] sigma,  [TEG] 6S, and Quantra). No study has compared the performances of these..

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Modified Ultrafiltration Should Not Be Routinely Used in Adult Cardiac Surgery

Abstract Pediatric Literature As the practice of ultrafiltration arose from pediatric cardiac surgery, much of the evidence to support MUF is from low-powered pediatric studies. Some early, single-center literature, as..

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Modified Ultrafiltration Is Beneficial for Adults Undergoing Cardiac Surgery

Abstract Hemodilution and Volume Overload The use of CPB necessitates priming of the CPB circuit, which is typically accomplished using 1-to-2 liters of a crystalloid solution. In addition, 1-to-3 liters..

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Cost-Effectiveness of Cell Salvage in Trauma Blood Transfusions

Abstract Introduction Despite the increasing amount of evidence supporting its use, cell salvage (CS) remains an underutilized resource in operative trauma care in many hospitals. We aim to evaluate the..

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How do we forecast tomorrows’ transfusion: Non-transfusional hemotherapy

Abstract Hemotherapy is the treatment of diseases by the use of blood or blood products from blood donation (by others of for oneself). It is clear that blood components transfusion..

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Contemporary practice and perception of autologous blood salvage in hepato-pancreatico-biliary operations: an international survey

Abstract Background This study aimed to assess contemporary knowledge, attitudes and behaviors around transfusion of intraoperative salvaged blood (sRBCt) during hepato-pancreatico-biliary (HPB) operations. Findings are meant to inform the design..

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Cytosorb Adsorption During Emergency Cardiac Operations in Patients at High Risk of Bleeding

Abstract Background The purpose of this study was to analyze the results of Cytosorb (CytoSorbents, Monmouth Junction, NJ) adsorption during emergency open heart operations in patients at high risk of..

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Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis

Abstract Background:   Ultrafiltration is used with cardiopulmonary bypass to reduce the effects of hemodilution and restore electrolyte balance. We performed a systematic review and meta-analysis to analyze the effect..

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Comparison of Prothrombin Complex Concentrate with Activated Factor VII Use for Bleeding Following Cardiopulmonary Bypass in Children

Abstract Objective This study aims to compare the efficacy and safety of activated recombinant factor VII (rFVIIa) and prothrombin complex concentrate (PCC) in the treatment of bleeding complications following surgery..

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In vitro study on the effect of fibrinogen γ-chain peptide-coated ADP-encapsulated liposomes on postcardiopulmonary bypass coagulopathy using patient blood

Abstract Background Fibrinogen γ-chain peptide-coated, adenosine 5'-diphosphate (ADP)-encapsulated liposomes (H12-ADP-liposomes) are potent hemostatic adjuvants that promote platelet thrombi formation at bleeding sites. Although we have reported the efficacy of these..

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Bleeding and Thrombotic Complications in COVID-19–Associated ARDS Requiring ECMO

Abstract BACKGROUND: We analyzed bleeding and thrombotic complications in COVID-19–associated ARDS requiring extracorporeal membrane oxygenation (ECMO). METHODS: This was a single-center observational study of adult subjects undergoing ECMO for COVID-19 (n = 67)..

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The effects of differing anticoagulant regimes on blood quality after cell salvage in coronary artery bypass grafting (CABG): a pilot…

Abstract Background Cell salvage reduces allogenic blood transfusion requirements in surgery. We present a pilot study exploring the impact of anticoagulant choice, citrate or heparin, on the quality of cell..

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