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Extracorporeal Membrane Oxygenation Support in Adult Patients with Calcium Channel Blocker Toxicity - An ELSO Registry Analysis

Abstract Background: Calcium channel blocker (CCB) toxicity presents a significant mortality risk, highlighting the need for effective treatment strategies such as ECMO. This study analyzes ELSO registry data to determine the..

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Functional and Social Recovery and Outcomes After Extracorporeal Membrane Oxygenation Support in COVID-19 Patients

Abstract With the COVID pandemic, veno-venous (VV) extracorporeal membrane oxygenation (ECMO) was implanted in many patients around the world. Data regarding follow-up and recovery of patients who are placed on..

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Awake insertion of transplant-bridging veno-arterial extracorporeal membrane oxygenation in a shocked patient with severe thrombocytopenia: a case report.

Abstract Background: Extracorporeal membrane oxygenation is an effective life support technology in treating patients with cardiorespiratory failure. It could be used as a bridge to recovery, potentially improving patient outcomes due..

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Multiple Pediatric Extracorporeal Membrane Oxygenation Runs and Futility. What Are the Limits?

Abstract Despite high mortality rates, pediatric extracorporeal membrane oxygenation (ECMO) redeployments are frequently discussed in everyday clinical care. We aim to investigate predictors of mortality in those patients. Clinical data..

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Ten Hour Donor Heart Ischemic Time with 10ºC Static Storage

Abstract Utilization of 10ºC static storage safely extended both ischemic time and travel radius in heart transplantation. A 57-year-old man with ischemic cardiomyopathy, a left ventricular assist device (LVAD), and..

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A novel miniaturized roller pump circuit for simulation of extracorporeal circulation

Abstract OBJECTIVES Extracorporeal circulation induces pronounced effects on haemostasis and rheology. To study these, an ex vivo simulation model is an attractive alternative but often requires large amounts of blood. We sought..

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SQUIRE-SIM (Standards for Quality Improvement Reporting Excellence for SIMulation)

Abstract Introduction  With increased incorporation of simulation-based methodologies into quality improvement activities, standards for reporting on simulation-specific elements in healthcare improvement research are needed. Methods  We followed established consensus process..

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Operating Room Extubation for Patients Undergoing Cardiac Surgery: A National Society of Thoracic Surgeons Database Analysis

Abstract Background The utility of operating room extubation (ORE) after cardiac surgery over fast-track extubation (FTE) within 6 hours remains contested. We hypothesized ORE would be associated with equivalent rates..

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An endothelium membrane mimetic antithrombotic coating enables safer and longer extracorporeal membrane oxygenation application

Abstract Thrombosis and plasma leakage are two of the most frequent dysfunctions of polypropylene (PP) hollow fiber membrane (PPM) used in extracorporeal membrane oxygenation (ECMO) therapy. In this study, a..

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VA-ECMO as a support therapy in massive acute pulmonary embolism treated with catheter-directed thrombolysis

Abstract Introduction: Acute pulmonary embolism (PE) leads to increased pulmonary vascular resistance and right ventricular afterload, resulting in right ventricular dysfunction (RVD). Stratification is crucial to early identify patients with elevated..

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Survival After Extracorporeal Cardiopulmonary Resuscitation Based on In-Hospital Cardiac Arrest and Cannulation Location: An Analysis of the Extracorporeal Life Support…

Abstract Objectives:  Explore whether extracorporeal cardiopulmonary resuscitation (ECPR) mortality differs by in-hospital cardiac arrest location and whether moving patients for cannulation impacts outcome. Design:  Retrospective cohort study. Setting:  ECPR hospitals..

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Hydrogel-coated and active clearance chest drains in cardiac surgery: real-world results of a single-center study

Abstract Purpose Cardiac surgery patients require chest drains for postoperative fluid drainage. Innovations in this field include chemical drain coating and manual clot extraction systems, aiming to provide reduced clotting..

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Acquired antithrombin deficiency in adult patients with postcardiotomy extracorporeal membrane oxygenation

Abstract Introduction This study aimed to investigate the relationship between acquired antithrombin deficiency in patients undergoing postcardiotomy extracorporeal membrane oxygenation (PC-ECMO) and thromboembolic or haemorrhagic events such as bleeding, peripheral..

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Risk factors for allogeneic red blood cell transfusion in adult spinal deformity surgery

Abstract Study Design Retrospective study. Purpose To investigate the risk factors for allogeneic red blood cell (RBC) transfusion in adult spinal deformity (ASD) surgery. Overview of Literature Studies have not..

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Complement system activation: bridging physiology, pathophysiology, and therapy

Abstract The complement system is a set of over 50 proteins that constitutes an essential part of the innate immune system. Complement system activation involves an organized proteolytic cascade. Overactivation..

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support. Yet, few data are avail-able to support..

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The Role of Veno-Arterial Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism: A Case Report

Abstract Introduction: Amniotic fluid embolism (AFE) is a catastrophic complication of pregnancy with high mortality rate. It is an inflammatory response leading to cardiovascular collapse. We present a case of successful..

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Relation between antithrombin-III activity and activated clotting time for cardiopulmonary bypass

Abstract Heparin resistance (HR) is observed before cardiopulmonary bypass (CPB), despite with normal antithrombin III (AT-III) levels. The relationships between preoperative AT-III activity and activated clotting time (ACT) after the..

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Hemodynamic Effects and Clinical Outcomes of Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO) in Cardiogenic Shock

Abstract Background: Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting via a multi-fenestrated..

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Hemodynamic Support in Sepsis

Abstract Sepsis is a dysregulated host response to infection responsible for life-threatening organ dysfunction.1  Along with early antimicrobial administration and source control, correction of hemodynamic derangements is a crucial aspect of..

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Students’ approaches to developing scientific communication skills

Abstract Science communication is a core skill for undergraduate science students to acquire in preparation for their future careers, but studies show that this skill is underdeveloped in science graduates...

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Heparin-Bead Extraction Enhanced Fluorogenic Aptamer–Thrombin Composite Reporter Enables Sensitive and Rapid Detection of Functional Antithrombin

Abstract Antithrombin (AT) deficiency in the extracorporeal circulation during cardiac surgery leads to uncontrolled inflammation and vascular damage in patients. AT levels decrease in sepsis, major trauma, extracorporeal membrane oxygenation,..

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Sourcebook update: using near-infrared spectroscopy to assess skeletal muscle oxygen uptake

Abstract Monitoring the metabolic cost or oxygen consumption associated with rest and exercise is crucial to understanding the impact of disease or physical training on the health of individuals. Traditionally,..

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Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery

Abstract Importance  Liberal oxygen (hyperoxia) is commonly administered to patients during surgery, and oxygenation is known to impact mechanisms of perioperative organ injury. Objective  To evaluate the effect of intraoperative hyperoxia compared..

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Cardiopulmonary Bypass Blood Flow Rates and Major Adverse Kidney Events in Cardiac Surgery: A Propensity Score-adjusted Before–After Study

Abstract Objectives Cardiac surgery associated-acute kidney injury is a common and serious postoperative complication of cardiac surgery, which is associated with increased postoperative morbidity and mortality. This study aimed to..

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“Not an ECMO Candidate”: An exploratory analysis of patients declined for VA-ECMO

Abstract Background: Patient selection for extracorporeal membrane oxygenation (ECMO) support is complex and associated with variability between clinicians. Disparities exist in ECMO use, with lower utilization in patients who are female,..

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Factors associated with acute kidney injury after on-pump coronary artery bypass grafting

Abstract Background Acute kidney injury (AKI) frequently occurs as a complication of cardiac surgery and cardiopulmonary bypass (CPB). Its prevalence and severity are determined by various preoperative and intraoperative factors...

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Overcoming Obstacles in Remote ECPR:A Success Story from Initial Resuscitation to LVAD

Abstract Introduction: In remote hospital settings, providing timely and effective extracorporeal cardiopulmonary resuscitation (ECPR) is challenging due to infrastructure limitations and accessibility issues. We are highlighting the importance of grab-and-go ECPR..

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Impact of a Daily Huddle on Safety in Perioperative Services

Abstract Background Communication failures contribute to quality gaps and may lead to serious safety events (SSEs) in the operating room (OR). Our perioperative services team experienced an increased rate of..

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Mitigating the Stigma of Severe Obesity: BMI ≥ 35 kg/m2 is not a Contraindication to Extracorporeal Support

Abstract Background: A body mass index (BMI) ≥ 35 kg/m² is traditionally a contraindication to extracorporeal support. We evaluated outcomes and quality of life (QoL) associated with veno-venous extracorporeal membrane oxygenation (VV-ECMO)..

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