Abstract Antithrombin (AT) deficiency in the extracorporeal circulation during cardiac surgery leads to uncontrolled inflammation and vascular damage in patients. AT levels decrease in sepsis, major trauma, extracorporeal membrane oxygenation,..
Read MoreAbstract The continuous measurement of percutaneous oxygen saturation (SpO2) enables diseases that cause hypoxemia to be detected early and patients’ conditions to be monitored. Currently, SpO2 is mainly measured using..
Read MoreAbstract Background and Objectives A plasma transfusion dose should be weight-based (10–20 mL/kg), which equates to three to four units in an average-sized adult; therefore, the transfusion of single units under..
Read MoreAbstract Alveolar de recruitment is a common problem during general anesthesia and operations. Pediatric cardiac surgery with cardiopulmonary Bypass is associated with interruption of ventilation and might enhance loss of..
Read MoreAbstract Background Decreasing variability in time-intensive tasks during cardiac surgery may reduce total procedural time, lower costs, reduce clinician burnout, and improve patient access. The relative contribution and variability of..
Read MoreAbstract Programme leaders in graduate medical education (GME) are responsible for the final stage of physician training, guiding the transition from supervised to independent practice. The influence of GME programme..
Read MoreAbstract Objectives Prior studies have examined the association between timing of cardiac surgery after with risk of , but this remains controversial. The purpose of this study was to investigate the association..
Read MoreAbstract BACKGROUND: Preoperative screening for iron deficiency is a part of patient blood management protocols. This systematic review, meta-analysis, and meta-regression reviews the association between nonanemic iron deficiency and postoperative..
Read MoreAbstract Introduction While newer heater-cooler technologies using ethylene glycol-based (GB) solutions during cardiothoracic surgery have become commercially available, there is a paucity of clinical data describing their effectiveness during cardiopulmonary..
Read MoreAbstract Rotary blood pumps in Extracorporeal Life Support (ECLS) applications are optimized for a specific design point. However, in clinical practice, these pumps are usually applied over a wide range..
Read MoreAbstract Introduction and importance Bleeding during pregnancy or during can cause significant morbidity and mortality for the mother and baby, this can be overcome by performing a (C-section) and . Although blood transfusions..
Read MoreAbstract Purpose Managing children undergoing cardiac surgery with cardiopulmonary bypass (CPB) presents a significant challenge for anesthesiologists. Machine Learning (ML)-assisted tools have the potential to enhance the recognition of patients..
Read MoreAbstract Objective Bleeding after cardiac surgery leads to poor outcomes. The objective of the study was to build the PeriOperative Bleeding Score in Cardiac surgery (POBS-Card) to predict bleeding after..
Read MoreAbstract Objective Systemic heparinization during cardiopulmonary bypass (CPB) can significantly affect thromboelastography (TEG). This study investigated the feasibility of adding protamine in vitro to allow assessment of coagulation status using the..
Read MoreAbstract Background Evidence supporting with unfractionated heparin (UFH) in patients with an intra-aortic balloon pump (IABP) to prevent remains limited, while bleeding risks remain high. Monitoring heparin in this setting with anti-factor..
Read MoreAbstract Calcium channel blocker (CCB) toxicity presents a significant mortality risk, highlighting the need for effective treatment strategies such as extracorporeal membrane oxygenation (ECMO). This study analyzes Extracorporeal Life Support..
Read MoreAbstract Purpose: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right ventricular injury (RVI)..
Read MoreAbstract Hemolysis-induced acute kidney injury (AKI) is attributed to heme-mediated proximal tubule epithelial cell (PTEC) injury and tubular cast formation due to intratubular protein condensation. Megalin is a multiligand endocytic..
Read MoreAbstract OBJECTIVES Adequate theoretical and practical training of prospective clinical perfusionists is essential for maintaining clinical standards and ensuring patient safety during cardiac surgery procedures. Perfusion schools play a crucial..
Read MoreAbstract Background This case report documents the first worldwide use of the Hybrid System from Spectrum Medical in a heart transplant procedure, focusing on its safety and efficacy. Traditional cardiopulmonary..
Read MoreAbstract Amniotic fluid embolism (AFE) is an obstetric complication that can result in acute circulatory failure during and after labor. The effectiveness of extracorporeal membrane oxygenation (ECMO) in AFE patients..
Read MoreAbstract Purpose: Patients receiving venoarterial extracorporeal membrane oxygenation (VA‑ECMO) frequently develop arte‑rial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets may also lead to harmful episodes of hypoxaemia...
Read MoreAbstract Data on perioperative extracorporeal membrane oxygenation (ECMO) in liver transplantation (LT) are scarce. ECMO has been used preoperatively, intraoperatively, and postoperatively for a variety of indications at our center...
Read MoreAbstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support [1, 2]. Yet, few data are avail-able..
Read MoreAbstract Introduction The primary aim was to describe the outcome, the compliance with inclusion criteria and the characteristics of patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is a high-risk and low-volume life support with increasing clinical study. However, heterogenous outcome definitions impede data assimilation into evidence to guide practice. The Academic..
Read MoreAbstract Heart transplantation and left ventricular assist devices (LVADs) have emerged as crucial interventions for end-stage heart failure, dramatically improving patient outcomes. This narrative review examines their historical context, indications,..
Read MoreAbstract Aims Current data are insufficient for the leading resuscitation societies to advise on the use of extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric out-of-hospital cardiac arrest (OHCA). The aim of..
Read MoreAbstract Aims This study explores the evolution of organ donation from patients treated with extracorporeal-cardiopulmonary-resuscitation (ECPR) for refractory out-of-hospital-cardiac-arrest (OHCA) and evaluates the public health benefits of a mature ECPR..
Read MoreAbstract Objectives To understand if red blood cell (RBC) transfusions are independently associated with a risk of mortality, prolonged , or infectious, cardiac, or renal morbid outcomes. Design A retrospective review...
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