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Extracorporeal membrane oxygenation for adults with respiratory failure secondary to cardiorespiratory disease: evolving indications and clinical practice

Abstract Extracorporeal membrane oxygenation (ECMO) can support patients with severe cardiorespiratory failure presenting with hypoxia who would otherwise have not survived. Patient selection for ECMO is challenging and relies on..

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Neurocognitive Dysfunction After Short (

Abstract Background It has long been held that the safe duration of hypothermic circulatory arrest (HCA) is at least 25 to 30 minutes. However, this belief is based primarily on..

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Hemodynamic Impact of the Trendelenburg Position: A Systematic Review and Meta-analysis

Abstract Objective To systematically evaluate the impact of the Trendelenburg position on hemodynamic parameters in adult patients. Design Systematic literature review and meta-analysis using PubMed and Medline. Setting All prospective..

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A perspective on the added value of red blood cells during cardiac hypothermic oxygenated perfusion

Abstract Hypothermic oxygenated perfusion (HOPE) is an emerging technique for donor heart preservation that is currently being studied in multiple clinical trials with promising results. When compared to HOPE for..

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Improving quality and outcomes of extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest: the Phoenix ECPR project

Abstract Background Survival for cardiac arrest remains poor, and the use of extracorporeal cardiopulmonary resuscitation (ECPR) has been suggested as a potential therapy to improve outcomes. Harefield Hospital has been performing..

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Lung injury in myocardial infarction-associated cardiogenic shock supported by venoarterial extracorporeal membrane oxygenation: a scoping review

Abstract Background Acute lung injury and acute respiratory failure are frequent complications of cardiogenic shock and are associated with increased morbidity and mortality. Even with increased use of temporary mechanical..

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Optimal antegrade cerebral perfusion flow in patients undergoing surgery for acute type A aortic dissection: A retrospective single-center analysis

Abstract Background Systemic hypothermia with bilateral antegrade selective cerebral perfusion (ASCP) is the preferred cerebral protective strategy for type A aortic dissection surgery. The optimal ASCP flow rate remains uncertain..

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Drawing and storing blood using a 3D printed bottle cap and a disinfected 500 mL drinking bottle: A proof-of-concept study

Abstract Background Today, with wars raging in Ukraine and the Middle East, the demand for blood is high. Despite this, few companies produce the necessary equipment to draw, store, and..

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Acute kidney injury

Abstract Acute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income..

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Considering veno-venous extracorporeal membrane oxygenation as a first-line strategy for rewarming in accidental hypothermia complicated by cardiac arrest - a…

Abstract Severe accidental hypothermia can lead to cardiac arrest. The most efficient method of resuscitating and warming is by ECMO (Extracorporeal Membrane Oxygenation). While the convention is to use VA..

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Paradoxical Hypotension After Inadvertent Intravenous Administration of Epinephrine

Abstract Epinephrine, the standard treatment for anaphylaxis, is a lifesaving medication that can cause detrimental complications due to wrong-dose or wrong-route errors. Although the known toxicities of epinephrine such as..

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Organ Utilization From Donors Following Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review of Graft and Recipient Outcome

Abstract Background.  The global shortage of solid organs for transplantation is exacerbated by high demand, resulting in organ deficits and steadily growing waiting lists. Diverse strategies have been established to..

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Residual Red Blood Cell Volume in Extracorporeal Blood Circuit after Hemodialysis: A Single-Center Study

Abstract Introduction: The factors contributing to blood loss during hemodialysis (HD) procedures remain underexplored. This study aimed to quantify blood loss during HD and identify the potential factors associated with it. ..

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A case of intraoperative arrest & mobile ECMO

Abstract Over the past two decades, extracorporeal membrane oxygenation (ECMO) has been increasingly used to support critical patients with cardiac and respiratory failure who fail to respond to conventional management...

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The European Board of Cardiovascular Perfusion statement on organ perfusion

Since 1991, the ‘European Board of Cardiovascular Perfusion (EBCP)’ has played a vital role in the European healthcare system by overseeing and promoting the field of cardiovascular clinical perfusion. Through..

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Compartmentalization of the Inflammatory Response in the Pericardial Cavity in Patients Undergoing Cardiac Surgery

Abstract The systemic inflammatory response after cardiopulmonary bypass has been widely studied. However, there is a paucity of studies that focus on the local inflammatory changes that occur in the..

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Andexanet Alfa–Associated Heparin Resistance in Cardiac Surgery: Mechanism and In Vitro Perspectives

Abstract BACKGROUND: Andexanet alfa (andexanet) is the only Food and Drug Administration–approved antidote for direct FXa (factor Xa) inhibitors but has been reported to cause resistance to unfractionated heparin (UFH)...

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Hemadsorption with CytoSorb®: focus on the latest experiences in cardiac surgery patients

Abstract Cardiac surgery patients are potentially exposed to an acute inflammatory host response with a huge release of both pro- and anti-inflammatory cytokines both through intrinsic (e.g., tissue damage, endothelial..

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Randomized Trial of Pulsatile and Nonpulsatile Flow in Cyanotic and Acyanotic Congenital Heart Surgery

Abstract Background The study objective was to determine the impact of cardiopulmonary bypass perfusion modalities on cerebral hemodynamics and clinical outcomes in congenital cardiac surgery patients stratified by acyanotic versus..

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Application comparison of paediatric myocardial protection procedures in arterial switch surgery

Abstract Background Reliable myocardial protection is essential for a good outcome after arterial switch operation. Patients and Methods We evaluated 56 neonates with arterial switch operation in this retrospective study...

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Short term outcomes of the first pediatric cardiac surgery program in Rwanda

Abstract Background While the number of cardiac surgery programs in sub-Saharan Africa are increasing, it is still insufficient. With only 0.08 pediatric cardiac surgeons per million people, few cardiac centers..

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Sevoflurane versus propofol on immediate postoperative cognitive dysfunction in patients undergoing cardiac surgery under cardiopulmonary bypass: a comparative analysis

Abstract Objective This study aims to compare the effects of sevoflurane (SEV) and propofol (PRO) on postoperative cognitive dysfunction (POCD) in patients undergoing cardiac surgery (CS) under cardiopulmonary bypass (CPB),..

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Machine learning approaches for improvement of patient safety in surgery

Abstract Traditional patient safety protocols are based on the historic principle of the Hippocratic oath intended to abstain from inflicting harm on our patients (”Primum non nocere”) []. In spite..

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Erythrocytes and Platelets Autotransfusion in High Hemorrhagic Risk Cardiac Surgery: A Single-Center Pilot Analysis of the Multicentric SEPIA Registry

Abstract Intraoperative cell salvage (IOCS) allows the collection, treatment, and retransfusion of shed blood from the surgical field and cardiopulmonary bypass (CPB) collector during cardiac surgery. This technique has been..

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Association of Anaesthetists guidelines: the use of blood components and their alternatives

Abstract Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri-operative outcomes. Considerable changes in the approaches to..

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Measuring the quality of surgery: should textbook outcomes be an off-the-shelf or a bespoke metric?

Abstract Measuring the quality of healthcare has become increasingly important, with surgery not exempt from such evaluation. As technological opportunities and novel developments broaden the range and complexity of treatments..

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Trial of Oxygen Delivery on Cardiopulmonary Bypass and Major Clinical Outcomes

Abstract Background Low oxygen delivery (DO2) on cardiopulmonary bypass has been associated with acute kidney injury. We sought to determine the association of intraoperative DO2, postoperative length of stay, and..

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Cell salvage for the management of postpartum haemorrhage

Abstract Rationale Postpartum haemorrhage (PPH), defined as a blood loss of 500 mL or more within 24 hours of birth, is the leading global cause of maternal morbidity and mortality...

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Women in cardiac surgery: a global workforce analysis

Abstract OBJECTIVES Cardiac surgery remains one of the most gender-imbalanced surgical specialties. Women constitute 6–11% of the North American workforce, while other regional data are scarce. Despite the acknowledged under-representation..

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Protein alterations in patients with delirium after cardiac surgery: An exploratory case-control sub-study of the VISION Cardiac Surgery Biobank

Abstract Background:  Delirium is an acute state of confusion associated with adverse postoperative outcomes. Delirium is diagnosed clinically using screening tools; most cases go undetected. Identifying a delirium biomarker would..

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