Abstract Background Venovenous extracorporeal membrane oxygenation (ECMO) is essential for patients with severe respiratory failure who do not respond to conventional mechanical ventilation. Adequate ECMO flow and safe circuit pressure..
Read MoreAbstract Mechanical circulatory support (MCS) devices are standard therapy for advanced heart failure, but modern systems lack standardized methods for setting critical parameters such as rotational speed and flow rate...
Read MoreAbstract Cardiopulmonary bypass (CPB) is an essential component of modern cardiac surgery, allowing surgeons to temporarily replace heart and lung function during complex procedures. One important technical aspect of CPB..
Read MoreAbstract Hospitals seeking to implement complex technologies like extracorporeal membrane oxygenation (ECMO) now have practical roadmaps thanks to Integration Health’s effort to provide guidance drawn from decades of clinical and..
Read MoreAbstract Clinically significant bleeding is a common complication of extracorporeal membrane oxygenation (ECMO), with bleeding observed in upwards of 40% of patients. Bleeding is strongly associated with systemic anticoagulation, which..
Read MoreAbstract Heart failure is a significant complication of chronic intravascular hemolysis, a condition characterized by red blood cells (RBCs) breakdown, leading to the release of acellular hemoglobin (Hb) and its..
Read MoreAbstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..
Read MoreAbstract The drainage cannula in a venoarterial extracorporeal membrane oxygenation (VA ECMO) circuit transfers venous blood from the patient to a pump. However, drainage cannulas are prone to thrombosis, leading..
Read MoreAbstract Heart transplantation (HT) and durable left ventricular assist device (LVAD) support are established surgical treatment options for patients with end-stage systolic heart failure (HF) and/or nonrecoverable cardiogenic shock. HT..
Read MoreAbstract Background: The degree of hypothermia during coronary artery bypass grafting (CABG) surgery may affect kidney injury. In this study we compared the effects of mild (MLD) and moderate (MOD) hypothermia..
Read MoreAbstract Post-cardiotomy cardiogenic shock (PC-CS) affects 2–6% of cardiac surgery patients. While survival rates keep improving, 40% of intensive care (ICU) survivors experience a “post-intensive care syndrome”, encompassing physical, cognitive,..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) provides life-saving support for patients with advanced cardiorespiratory failure, yet unanticipated difficulties with peripheral cannulation can delay therapy. This study describes challenging neonatal and..
Read MoreAbstract The perioperative management in adult cardiac surgery patients remains highly variable across centres and regions. The APECx study (Anaesthesia, Perfusion and surgical practicEs in Cardiac surgery) aims to describe..
Read MoreAbstract We aim to provide evidence-based clinical practice guidelines for the use of VV ECMO in adult patients across Australia and New Zealand. Developed by a multidisciplinary panel of clinicians..
Read MoreAbstract Introduction Delirium is a common, distressing, and dangerous complication after cardiac surgery with cardiopulmonary bypass (CPB) with few modifiable risk factors. This study aims to determine the association between..
Read MoreAbstract Stone heart syndrome (SHS) is a rare but catastrophic complication of cardiac surgery, characterized by irreversible ischemic myocardial contracture following prolonged global myocardial ischemia, and is almost uniformly fatal..
Read MoreAbstract Background Postoperative bleeding following cardiopulmonary bypass (CPB) remains a significant challenge. Although viscoelastic testing is increasingly used, the relative contributions of fibrinogen, platelet count and clot firmness to blood..
Read MoreAbstract Objective Coronary artery bypass grafting using cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery disease. Research suggests supplementing the cardioplegia solution with propofol may be..
Read MoreAbstract Background Nitric oxide (NO) is reported to play several protective roles in the inflammatory response and ischemia/reperfusion injury. This study evaluated the effect of nitric oxide (NO) on postoperative..
Read MoreAbstract Objectives Clinical practice in anticoagulation management, particularly in heparin administration, monitoring, reversal and haemostasis, is known to differ significantly. To better characterize this variability, we conducted a Europe-wide survey..
Read MoreAbstract Objectives Clinical practice in anticoagulation management, particularly in heparin administration, monitoring, reversal and haemostasis, is known to differ significantly. To better characterize this variability, we conducted a Europe-wide survey..
Read MoreAbstract Background Patients with severe respiratory failure frequently suffer from concomitant haemodynamic compromise. By correcting respiratory acidosis and permitting reduced mechanical ventilation pressures, venovenous extracorporeal membrane oxygenation (V-V ECMO) may..
Read MoreAbstract Peri-device leak and device-related thrombus remain key challenges of current left atrial appendage occlusion (LAAO) owing to the incompatibility between the solid occluder and the left atrial appendage (LAA). Here..
Read MoreAbstract Acute respiratory distress syndrome (ARDS) is a major cause of morbidity and mortality despite decades of progress in ventilatory support. Mechanical ventilation, while essential for oxygenation, may exacerbate lung..
Read MoreAbstract Introduction: The absence of a congenital heart surgery national registry limits understanding of access, surgical volume, and mortality. This study analyzes the Brazilian administrative data to assess procedural distribution, outcomes,..
Read MoreAbstract Background Socioeconomic inequalities have been associated with adverse outcomes in critically ill COVID-19 patients. Whether these disparities extend to the most severe ARDS patients treated with ECMO, regardless of..
Read MoreAbstract Objectives Data on the role of obesity in patients undergoing minimally invasive cardiac surgery are sparse, and the longitudinal observations after minimally invasive mitral valve repair (MI-MVr) in obese..
Read MoreAbstract Introduction Regional citrate anticoagulation (RCA) is the recommended first-line strategy for continuous renal replacement therapy (CRRT) circuits. Acute kidney injury is common in patients undergoing venoarterial extracorporeal membrane oxygenation..
Read MoreAbstract Background Intravenous amino acids (AA) reduce acute kidney injury (AKI) in adult patients undergoing cardiac surgery. Because the optimal duration of AA infusion is unknown, we investigated the effect..
Read MoreAbstract Background: Musculoskeletal disorders (MSDs) are highly prevalent among healthcare workers, particularly nurses, with reported prevalence rates ranging from 57% to 93%. Perfusionists are highly specialized healthcare professionals responsible for operating..
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