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Use of Temporary Ventricular Assist Devices for Left Ventricular Unloading During Venoarterial Extracorporeal Membrane Oxygenation Support

Venoarterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support for patients in refractory cardiogenic shock. Initiation of VA ECMO often results in increased left ventricular (LV) afterload as..

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Blood Transfusions are Associated With Prolonged Mechanical Ventilation Following Cardiac Surgery in Neonates

Abstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion..

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The progress and trends of the mechanism of cardiopulmonary bypass-associated acute lung injury: A narrative review

Abstract Studies into the mechanisms of cardiopulmonary bypass-associated acute lung injury have not presented breakthroughs for many years, resulting in the stagnation of management strategies and clinical medicine measures. This..

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The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs. These complications are primarily driven by hemolysis,..

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Clinical Outcomes of Cardiogenic Shock Patients Supported with VA-ECMO: Insights from the Cardiogenic Shock Working Group

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) use for cardiogenic shock (CS) is increasing worldwide despite conflicting results from randomized trials, which focused on myocardial-infarction related CS (MI-CS). Methods We..

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Is Cardiac Surgery Safe During GenAI exceeds clinical experts in predicting acute kidney injury following paediatric cardiopulmonary bypassPregnancy?

Abstract The emergence of large language models (LLMs) opens new horizons to leverage, often unused, information in clinical text. Our study aims to capitalise on this new potential. Specifically, we..

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Network meta-analysis of cardioplegic methods, in elective isolated coronary artery bypass grafting

Abstract Background Cardioplegic arrest can be induced by various methods, fueling a long-standing controversy about their comparative merit. We aim to compare cardioplegic methods in coronary artery disease. Methods PubMed,..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion?

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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Perioperative use and accuracy of continuous glucose monitoring: A systematic review

Abstract Perioperative impairment of glycaemic control significantly increases the risk of major postoperative complications. The use of continuous glucose monitoring (CGM) has demonstrated benefits in glycaemic control, but its use..

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Brain First: Carotid Artery Access for Cerebral and Arterial Perfusion in Complex Aortic Surgery

Abstract The common carotid artery (CCA) is an easily accessible means of providing cerebral and systemic perfusion during complex aortic surgery. Our technique for using CCA perfusion through a graft..

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Extracorporeal and Conventional Cardiopulmonary Resuscitation and Low‐Flow Duration: Insights From a Nationwide Hospital‐Based Registry Study in Japan (JAAM‐OHCA Registry)

Abstract Background The optimal low‐flow duration (LFD) for extracorporeal cardiopulmonary resuscitation (ECPR) and conventional cardiopulmonary resuscitation (CCPR) remains unclear. We evaluated the impact of LFD on neurological outcomes based on..

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Mixed Venous Oxygen Saturation Has a Poor Association with Cardiac Index during Early Intensive Care Unit Stay after Cardiac Surgery

Abstract Objectives Our aim was to assess the association between mixed venous oxygen saturation (SvO2) and cardiac index (CI) among cardiac surgical patients during the initial 4 hours in the..

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Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective…

Abstract Background Acute kidney injury (AKI) is a frequent and severe complication following cardiac surgery, particularly in patients with impaired kidney function. The existing Kidney Disease: Improving Global Outcomes (KDIGO)..

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Outcomes Following Perioperative Stroke in Cardiac Surgery Patients: A Retrospective Cohort Study

Abstract Objectives To identify independent predictors of 30-day mortality, adverse discharge, and length of hospital stay following a perioperative stroke among cardiac surgical patients, and to measure trends in outcomes..

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Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol

Abstract Introduction Cardiac surgery remains a high-risk procedure for bleeding despite advances in patient blood management. Conventional centrifugation-based autotransfusion devices primarily recover red blood cells, losing platelets and coagulation factors. The..

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Early detection of mesenteric ischemia in critically ill patients following cardiac surgery

Abstract Mesenteric ischemia (Me-Is) is a severe complication with high mortality after cardiac surgery. We examined whether intestinal fatty acid binding protein (I-FABP) might serve as a biomarker for early..

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Risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation support in adults based on the MIMIC-IV database

Abstract Objective:   To identify risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation (ECMO) support in adults and to develop a predictive model based on these factors...

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Perspectives on the Predictive Role of PvCO2 × Ve/Q for Hyperlactatemia During Cardiopulmonary Bypass

Abstract We read with great interest the article by Kowara et al.,[] which highlights the potential of PvCO2 × Ve/Q as a key predictive marker for hyperlactatemia during cardiopulmonary bypass (CPB). This..

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The impact of systemic inflammation index on prolonged mechanical ventilation after cardiac surgery: a retrospective study

Abstract Background Despite advancements in surgical techniques and intensive care management, the incidence of prolonged mechanical ventilation (PMV) following cardiac surgery remains a significant concern. Objectives Investigate the relationship between..

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Early single center experience with cerebral embolic protection in high-risk cardiac surgery

Abstract Cerebral embolic protection (CEP) devices may be a tool to mitigate the perioperative stroke risk in cardiac surgery. However, studies are limited. The aim of this study was to..

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80 Years After the First Blalock-Thomas-Taussig Shunt: Cardiac Research in Canines That Saved Lives

Abstract Many of the pivotal early achievements in cardiac surgery were possible because of research using canine models. Specific advances attributed to canine experiments include the use of hypothermia, cardiopulmonary..

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Effects of increased cardiopulmonary bypass pump flow on renal filtration, perfusion, oxygenation and tubular injury in cardiac surgical patients -…

Abstract Background:  Cardiac surgery with cardiopulmonary bypass (CPB) is associated with impaired renal oxygenation and acute kidney injury. We investigated whether a higher than our standard blood flow during CPB..

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Extracorporeal life support for adult patients with ARDS

Abstract Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current..

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Incidence, kinetics, and clinical impact of thrombocytopenia in venovenous ECMO: insights from the multicenter observational PROTECMO study

Abstract Background Thrombocytopenia is a recognized risk factor for bleeding during extracorporeal membrane oxygenation (ECMO). This study determines the incidence, risk factors, and clinical relevance of thrombocytopenia and platelet transfusions..

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Sleep protects the heart after myocardial infarction through a neuro-immune axis: time to implement healthy sleep for cardiovascular prevention?

Abstract Sleep is essential for human health and represents an active state of unconsciousness that plays a critical role in restoring brain and body functions, as well as regulating the..

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The effect of cardiopulmonary bypass on hemorheology: Evaluation of clinical outcomes

Abstract Background During cardiopulmonary bypass (CPB), which is frequently utilized in open-heart surgery, the maintenance of circulation in a non-physiological environment may lead to alterations in the properties of circulating..

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Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries

Abstract Background The global prevalence of congenital heart disease (CHD) is increasing. Research on patient-reported outcomes (PROs) predominantly originates from high-income countries, resulting in an incomplete understanding of the true global..

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Hydroxocobalamin for vasoplegia in cardiac surgery: a retrospective cohort analysis

Abstract Background Vasoplegia during cardiac surgery is common and associated with perioperative mortality. Hydroxocobalamin is a catecholamine-sparing approach for treating vasoplegia. However, there is currently limited evidence to inform its..

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Contemporary use and safety of prepartum autologous blood donation: A retrospective cohort study in Quebec, Canada

Abstract Background Autologous blood donation (ABD) can be indicated in pregnant individuals with rare blood groups. Yet, unlike hospitals, some blood establishments are reluctant to collect ABDs in this population...

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Storage duration of packed red blood cells transfused during veno-venous extracorporealmembrane oxygenation is associatedwith elevated pulmonary artery pressureand lung injury…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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