Archives

Perfusfind S.L.

Abstract Background and Aims To date, thromboelastometry has not been investigated as an assay to monitor profound heparin anticoagulation, such as is required for a safe cardiopulmonary bypass (CPB). The..

Perfusfind S.L.

Abstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasing worldwide. Patients with cardiogenic shock were the first indication for VA-ECMO according to the Extracorporeal Life Support Organization (ELSO)..

Perfusfind S.L.

Abstract Background There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed..

Perfusfind S.L.

Abstract Purpose Tissue factor pathway inhibitor (TFPI) is an intrinsic anticoagulant factor, and its plasma concentration is elevated by heparin administration. Because several hours are required to return to normal..

Perfusfind S.L.

Abstract Objectives:  Establishing an effective “chain of survival” for out-of-hospital cardiac arrest (OHCA) requires addressing gender disparities, which have been reported in both prehospital and in-hospital treatments. However, evidence of..

Perfusfind S.L.

Abstract Objective We test the hypothesis that pediatric arterial (“peds art”) cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer..

Perfusfind S.L.

Abstract SINCE THE FIRST lung transplant in 1963 and the introduction of extracorporeal membrane oxygenation (ECMO) as a bridge to transplant (BTT) in 1977, both have advanced remarkably. Lung transplantation is now..

Perfusfind S.L.

Abstract Background: Delirium after cardiac surgery is associated with poor outcomes. Cardiopulmonary bypass (CPB) increases blood-brain barrier (BBB) permeability and neuroinflammation, contributing to delirium. While microglial activation after CPB has..

Perfusfind S.L.

Abstract Background and Objective Pulsatile blood flow is considered more potential for delivering hemodynamic energy and enhancing microcirculatory perfusion in patients compared to non-pulsatile flow in ECMO. This study aims..

Perfusfind S.L.

Abstract Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies..

Perfusfind S.L.

Abstract Objectives:  To evaluate the feasibility of randomizing children on extracorporeal membrane oxygenation (ECMO) to one of two prophylactic platelet transfusion thresholds. Design:  Randomized controlled trial. Setting:  Ten ECMO centers..

Perfusfind S.L.

Abstract Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid...

Perfusfind S.L.

Abstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..

Perfusfind S.L.

Abstract Aim To assess health care professionals’ knowledge and opinions regarding extracorporeal membrane oxygenation (ECMO) use, training, standards, and resource availability. Methods This cross-sectional study employed an online self-administered survey..

Perfusfind S.L.

Abstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..

Perfusfind S.L.

Abstract Objectives:  This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..

Perfusfind S.L.

Abstract Background and Aims Pediatric heart transplantation remains hampered by the limited availability of donor organs. The introduction of ABO-incompatible (ABOi) heart transplantation for infants in the early 2000s expanded..

Perfusfind S.L.

Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become an essential life-saving therapy for patients with refractory cardiogenic shock, cardiac arrest, and severe cardiopulmonary failure. Despite its expanding use and..

Perfusfind S.L.

Abstract Pulmonary hypertension is a risk factor for increased morbidity and mortality in cardiac surgery. The use of a combination of inhaled vasodilator agents could have an improved effect on..

Perfusfind S.L.

Abstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..

Perfusfind S.L.

Abstract Cardiogenic shock (CS) remains a high-mortality condition that demands rapid diagnosis, coordinated multidisciplinary management, and timely initiation of mechanical circulatory support. As more institutions implement dedicated CS teams, substantial..

Perfusfind S.L.

Abstract Purpose Accurate hemodynamic monitoring is essential for personalized care in surgical and intensive care unit (ICU) settings, and radial artery catheters are the gold standard. Nevertheless, central-to-peripheral arterial blood..

Perfusfind S.L.

Abstract Background: The estimated incidence of acute kidney injury requiring renal replacement therapy (RRT), mainly continuous RRT (CRRT), in patients necessitating extracorporeal membrane oxygenation (ECMO) is approximately 50%. Currently, two..

Perfusfind S.L.

Abstract Computational fluid dynamics (CFD) is increasingly important in biomedical engineering; however, its use in medical device design remains constrained by regulatory requirements for model validation and verification. To address..

Perfusfind S.L.

Abstract Despite the refinement in guidelines and improving outcomes, a subset of patients with septic shock fails to respond to treatment and progresses into refractory septic shock with an associated..

Perfusfind S.L.

Abstract BACKGROUNDS  In patients with cardiac surgery under cardiopulmonary bypass (CPB), postoperative inflammation is a driver of adverse outcomes. Endotoxaemia is one of the factors thought to trigger this inflammatory..

Perfusfind S.L.

Abstract In losing Lucian Leape to heart failure last 30 June, at the age of 94 years, we lost a rare physician whose insights fundamentally changed how clinicians and the..

Perfusfind S.L.

Abstract Hydrogen has emerged as a therapeutic agent in inflammatory critical illnesses due to its potential to modulate inflammation and oxidative stress. However, its role in extracorporeal membrane oxygenation (ECMO),..

Perfusfind S.L.

Abstract Objectives Peripheral nerve injury (PNI) is a clinically significant but frequently under-recognized complication after cardiac surgery and catheterization, contributing to postoperative morbidity. While PNI has been well characterized in..

Perfusfind S.L.

Abstract Refractory ventricular arrhythmias and cardiac arrest in younger patients are rare, life-threatening events, particularly when standard resuscitation fails. Extracorporeal membrane oxygenation (ECMO) provides temporary circulatory support, enabling hemodynamic stabilization,..